Neogen Dermalogy A-Clear Toner for combination skin

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Questions and answers

What the research says

• Topical 5% tea tree oil gel significantly improved total acne lesions and acne severity index compared to placebo in 60 patients with mild to moderate acne vulgaris, showing 3.55 times and 5.75 times greater efficacy respectively.

  Indian Journal of Dermatology, Venereology and Leprology, 2007

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Lactobacillus-fermented Chamaecyparis obtusa reduced inflammatory acne lesions by 65.3% compared to 38.2% with tea tree oil in 34 patients over 8 weeks, demonstrating superior efficacy, faster onset, and safety.

  Dermatology, 2014

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.

  Journal of Cosmetic Dermatology, 2025

• Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.

  CMAJ, 2010

• A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.

  BioMed Research International, 2020

• Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.

  Journal of Cosmetic Dermatology, 2024

• Topical herbal treatments including lemon balm, olive leaf extract, propolis, and sage-rhubarb cream reduce pain, swelling, lesion size, and healing time in patients with herpes labialis compared with placebo or acyclovir.

  Journal of Integrative and Complementary Medicine, 2025

• Topical oleuropein formulations reduced erythema, transepidermal water loss, and blood flow by approximately 22%, 35%, and 30% in healthy volunteers with UVB-induced erythema.

  International Journal of Cosmetic Science, 2008

• An oil-in-serum formulation containing olive extract standardized in hydroxytyrosol improved skin barrier function and significantly reduced hyperpigmentation in participants with post-inflammatory hyperpigmentation after 45 days of application.

  AAPS PharmSciTech, 2026

• Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks.

  International Journal of Dermatology, 2000

• Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone.

  Dermatologic Surgery, 2017

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism.

  Evidence-based Complementary and Alternative Medicine, 2015

• Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo.

  Experimental Dermatology, 2015

• Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.

  Advanced Science, 2025

Ingredients

Water, Lauryl Hydroxysultaine, Sodium Chloride, Acrylates Copolymer, Potassium Cocoyl Glycinate, Disodium Cocoamphodiacetate, Sodium Methyl Cocoyl Taurate, Potassium Cocoate, Salicylic Acid, Sodium Benzoate, Melaleuca Alternifolia Tree Oil Leaf, Hexylene Glycol, Disodium Edta, Citric Acid, Guaiazulene, Gluconolactone, Calamine, Panthenol, Capryloyl Salicylic Acid, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Glycolic Acid, Butylene Glycol, 1,2-Hexanediol, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Madecassoside, Melaleuca Alternifolia Tree Leaf Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.