MISSHA Time Revolution Night Repair Probio Ampoule for oily skin
Bifida Lysate Ferment
Niacinamide
Sodium Hyaluronate
Probio Lactobacillus Complex
Panthenol
Average
- AverageOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for oily skin as niacinamide helps regulate sebum production and butylene glycol provides hydration, though it lacks ingredients for optimal oil control.
- The formula includes glycerin and Anthemis Nobilis Oil Flower for general hydration and soothing, which are supportive for oily shine but not targeted for its primary concern.
- The product is safe for your oily skin due to the absence of harsh ingredients and the presence of soothing agents like Bifida Lysate Ferment and Niacinamide.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
People Say
★4.6Overall rating based on 5.0k+ reviewsThis ampoule is frequently praised for delivering a 'glass skin' effect overnight, making dry and mature skin appear plump, hydrated, and glowing. A very large amount of data suggests that while it's a highly effective and affordable alternative to luxury serums, the high concentration of fermented ingredients may cause breakouts in individuals with fungal acne or sensitivities.
Highlights
Instant Glow Mostly Mentioned
- “woke up with a glow”
- “skin looks radiant”
- “gives glass skin effect”
- “banished dullness”
Deep Hydration Often Mentioned
- “plumps up fine lines”
- “skin feels baby soft”
- “very moisturizing for dry skin”
- “velvety finish”
Lightweight Texture Often Mentioned
- “sinks in immediately”
- “non-greasy finish”
- “layers well under cream”
- “lightweight consistency”
Texture Improvement Sometimes Noted
- “smoothed out texture”
- “pores look smaller”
- “skin feels stronger”
- “healed my barrier”
Value for Money Sometimes Noted
- “fraction of the price of ANR”
- “best affordable dupe”
- “great value for ingredients”
- “luxurious feel for cheap”
Breakouts & Reactions Sometimes Noted
- “caused cystic acne”
- “triggered fungal acne”
- “broke me out immediately”
- “tiny whiteheads appeared”
Fragrance & Oils Sometimes Noted
- “smell is too strong”
- “essential oils irritated my skin”
- “dislike the floral scent”
- “wish it was fragrance-free”
Dropper Issues Rarely Noted
- “dropper is finicky”
- “hard to get product out”
- “bottle design is annoying”
- “pipette doesn't work well”
Ineffective for Some Rarely Noted
- “did nothing for me”
- “weaker than the original”
- “just glorified water”
- “saw no difference”
Sticky Residue Rarely Noted
- “leaves a sticky film”
- “feels tacky”
- “takes time to dry down”
- “hair sticks to face”
Sources: lovi.care, iherb.com, amazon.com, sokoglam.com, yesstyle.com, youtube.com, and more
Questions and answers
How well does MISSHA Night Repair Probio Ampoule work for oily skin?
Which ingredients make this serum a good fit for oily skin?
Niacinamide helps regulate sebum production, and butylene glycol provides hydration to support oily skin. However, this product needs targeted oil-control ingredients, zinc, and a stronger combination of pore-clearing and barrier-supporting components to achieve an optimal fit for oily skin.
What does Bifida Ferment Lysate do for oily skin?
Bifida Ferment Lysate helps strengthen the outer skin layer and calm redness, making it a good fit for oily skin that gets easily irritated. It also provides antioxidant support and helps keep skin defenses balanced.
Journal of Cosmetic Dermatology, 2023Experimental Dermatology, 2010
What does Niacinamide do for oily skin?
Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Journal of Cosmetic and Laser Therapy, 2006Antioxidants, 2021
Where does this serum go in a skincare routine for oily skin?
This treatment goes in the evening routine after cleansing and toning, and before your moisturizer. Oily skin of this type needs targeted oil-controlling ingredients to properly manage excess shine.
Can I use this serum with retinol, and in what order?
You can use this treatment alongside retinol by applying the serum first to calm and hydrate your skin, followed by your retinol product. It is unlikely to cause irritation due to its gentle, soothing ingredients, but oily skin of this type works best with products that also offer targeted oil control.
How often should I use this serum?
You can use this treatment in your evening routine, applying it after cleansing and toning. This product offers moderate suitability for oily skin, so an oily skin type needs targeted oil-control ingredients and sebum-balancing actives to manage excess shine best.
Can this serum clog pores, cause breakouts or purging for oily skin?
This serum may occasionally cause breakouts or reactions on oily skin, as some reviewers note and the formula lacks targeted oil control ingredients. Oily skin needs products with specialized balancing ingredients and lightweight hydrators to keep pores clear and manage shine.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Dipropylene glycol, propylene glycol, and butylene glycol increased molecular mobility in stratum corneum lipids and affected keratin filaments, with butylene glycol and propylene glycol providing significant permeation enhancement.
Journal of Controlled Release, 2022A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.
Journal of Cosmetic Dermatology, 2023Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Probiotic-derived lotion successfully reduced inflammatory acne lesion counts and erythema index comparably to 2.5% benzoyl peroxide in patients with mild-to-moderate acne vulgaris, while causing fewer side effects.
Journal of Cosmetic Dermatology, 2022Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.
International Journal of Medical Sciences, 2021Lactobacillus plantarum extracellular vesicles modulated extracellular matrix related gene expression in vitro and suppressed wrinkle formation and pigmentation in clinical trials.
Current Issues in Molecular Biology, 2022Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000
Why other serums fit oily skin better
Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Bifida Lysate Ferment, Butylene Glycol, Glycerin, Propanediol, Betaine, Water, Niacinamide, Pentylene Glycol, 1,2-Hexanediol, Diethoxyethyl Succinate, Chondrus Crispus Extract, Squalane, Panthenol, Polyglyceryl-10 Laurate, Saccharum Officinarum Extract, Hydrogenated Lecithin, Carbomer, Tromethamine, Xanthan Gum, Polyquaternium-51, Ethylhexylglycerin, Adenosine, Dextrin, Theobroma Cacao Extract, Beta Vulgaris Root Extract, Brassica Oleracea Capitata Leaf Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Solanum Melongena Fruit Extract, Blueberry Fruit Extract, Bergamot Oil Fruit, Disodium Edta, Sodium Hyaluronate, Lactobacillus Soybean Extract Ferment, Leuconostoc Radish Root Ferment Filtrate, Bifida Ferment Filtrate, Lactobacillus Ferment, Lactobacillus Lysate Ferment, Lactobacillus Acerola Cherry Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Pelargonium Graveolens Oil Flower, Helianthus Annuus Seed Oil Sunflower Seed Oil, Citrus Aurantium Dulcis Peel Oil, Lavandula Angustifolia Oil Lavender Oil, Lupinus Albus Seed Extract, Aspergillus Ferment, Swiftlet Nest Extract, Anthemis Nobilis Oil Flower, Sandalwood Oil, Tocopherol, Ceramide Np, Cholesterol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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