# MISSHA Time Revolution Night Repair Ampoule for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [MISSHA](https://lovi.care/skincare/ie/brands/missha)
Category: [Serums and treatments](https://lovi.care/skincare/ie/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for combination skin due to the presence of Bifida Ferment Lysate and Niacinamide, which provide barrier repair and seboregulation benefits, but may not fully address all concerns for your oily shine.
- The inclusion of retinol and adenosine provides excellent treatment for minimizing fine lines and wrinkles, offering visible anti-aging effects.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Bifida Lysate Ferment, Niacinamide, Retinol, Copper Tripeptide-1, Ubiquinone

## What the research says

- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- Topical application of CoQ10 improves mitochondrial function in aging skin in vivo, combating cellular signs of aging caused by an age-dependent shift to a functionally anaerobic energy metabolism. ([BioFactors, 2008](https://pubmed.ncbi.nlm.nih.gov/19096122/))
- Encapsulating coenzyme Q10 in lipid nanoparticles for topical use improves skin compatibility, protects against degradation, increases skin penetration, and provides controlled release to counteract aging effects. ([Colloids and Surfaces. B, Biointerfaces, 2023](https://pubmed.ncbi.nlm.nih.gov/37574615/))
- Review of topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles highlights their improved bioavailability, chemical stability, skin absorption, and photoprotective effects. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34206935/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on a very large amount of data, this anti-aging overnight treatment is highly regarded for its ability to deeply hydrate, plump, and brighten the skin, significantly improving texture and reducing fine lines, particularly for those with dry, mature, or dull complexions. While generally well-tolerated, a moderate number of users with sensitive or acne-prone skin reported experiencing breakouts or irritation, and a small number noted a sticky or oily feel and a noticeable herbal scent.

- Liked: Deeply hydrates skin (mostly mentioned)
- Liked: Brightens and adds glow (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Affordable luxury dupe (sometimes noted)
- Disliked: May cause breakouts (sometimes noted)
- Disliked: Feels sticky or oily (rarely noted)
- Disliked: Noticeable herbal scent (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does MISSHA Night Repair Ampoule work for combination skin?

This product works moderately well for combination skin because it helps strengthen your skin barrier and control oil, though it may not fully address all your oily shine. A treatment of this type for combination skin needs effective ingredients like niacinamide and zinc PCA or propolis to manage oiliness and enhance radiance while keeping the skin balanced.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### Which ingredients make this serum a good fit for combination skin?

Bifida Lysate Ferment and Niacinamide help make this serum a fit by strengthening your skin barrier and helping manage oil, though a product of this type for combination skin needs ingredients like propolis or zinc PCA to better handle oily shine while keeping the skin balanced and radiant.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### What does Bifida Ferment Lysate do for combination skin?

Bifida Ferment Lysate helps strengthen the skin barrier and calm irritation, making it a good fit for combination skin that is prone to sensitivity. This ingredient works by supporting the skin defenses, keeping moisture locked in, and helping to reduce redness.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and toning, followed by a moisturizer. A product for this skin needs barrier-repairing and oil-balancing ingredients like bifida ferment lysate and niacinamide to help manage both dry areas and oily shine.

### Can I use this serum with AHA, and in what order?

You can use this treatment alongside an AHA by applying your AHA first, waiting for it to absorb, and then following with this product. Because both ingredients can be strong, introducing them gradually helps your combination skin avoid irritation.

### How often should I use this serum?

This treatment is used in the evening as part of your routine. A product of this type for combination skin needs ingredients that repair the skin barrier and balance oil production while minimizing fine lines.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This product may cause breakouts for combination skin, as reviewers report moderate complaints about this issue. A product for this skin needs balancing ingredients that control oily shine while keeping the skin calm and smooth.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/ie/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — €14.94 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €52.57 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/ie/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €385.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ie/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €56.86 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/ie/p/la-mer/the-tonic/for/combination-skin) — Superior fit — €115.30 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ie/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — €16.50 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Water, Bifida Lysate Ferment, Glycereth-26, Juniperus Chinensis Xylem Extract, Sorbus Commixta Extract, Bis-Peg-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Glycerin, Niacinamide, Betaine, Leuconostoc Radish Ferment Filtrate, Cyclopentasiloxane, Ethyl Hexanediol, Dimethicone, Grifola Frondosa Extract Ferment Filtrate Maitake Extract Ferment Filtrate Ophioglossum Vulgatum Extract Ferment Filtrate, Peg-11 Methyl Ether Dimethicone, Peg-40 Hydrogenated Castor Oil, Ppg-26-Buteth-26, Polysorbate 20, Carbomer, Glyceryl Caprylate, Triethanolamine, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Dimethicone Vinyl Dimethicone Crosspolymer, Hydrolyzed Rice Extract, Lactobacillus Rice Ferment Filtrate, Portulaca Oleracea Extract, Sea Water, Sodium Hyaluronate, Octyldodecanol, Carthamus Tinctorius Oleosomes, Acacia Arabica Bark Extract Stem, Hydrolyzed Extensin, Adenosine, Xanthan Gum, Aronia Arbutifolia Extract, Beta Vulgaris Root Extract, Brassica Oleracea Capitata Leaf Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Blueberry Fruit Extract, Dipropylene Glycol, Echium Plantagineum Seed Oil, Tocopheryl Acetate, Cyclomethicone, Hydrogenated Lecithin, Disodium Edta, Ascorbyl Tetraisopalmitate, Dextrin, Lactobacillus Ferment, Lactococcus Lysate Ferment, Laminaria Digitata Extract, Manilkara Multinervis Leaf Extract, Theobroma Cacao Seed Extract, Lauryl Methacrylate Glycol Dimethacrylate Crosspolymer, Saccharomyces Ferment Filtrate, Lactobacillus Soybean Extract Ferment, Glyceryl Polyacrylate, Saccharomyces Viscum Album Extract Ferment Mistletoe Extract Ferment, Yeast Extract Ferment, Pogostemon Cablin Oil, Dimethiconol, Cardiospermum Halicacabum Vine Extract Flower Leaf, Helianthus Annuus Seed Oil Sunflower Seed Oil, Pseudoalteromonas Extract Ferment, Alpha-Glucan Oligosaccharide, Limnanthes Alba Seed Oil, Hydrolyzed Wheat Protein, Beta-Sitosterol, Panthenol, Hydrolyzed Soy Protein, Propylene Glycol, Cholesterol, Ceteth-24, Choleth-24, Glyceryl Arachidonate, Glyceryl Linoleate, Glyceryl Linolenate, Ubiquinone, Hydroxypropyltrimonium Maltodextrin Crosspolymer, Cetyl Phosphate, Caprylic Capric Triglyceride, Macadamia Ternifolia Seed Oil, Retinol, Lecithin, Phenoxyethanol, Cucumis Melo Fruit Extract, Amaranthus Caudatus Seed Extract, Biotin, Brassica Campestris Sterols, Peg-5 Rapeseed Sterol, Sodium Ascorbyl Phosphate, Tripeptide-10 Citrulline, Acetyl Hexapeptide-8, Bht, Ceteth-3, Ceteth-5, Copper Tripeptide-1, Silica, Tripeptide-1
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule/for/combination-skin (this page)
- Germany: https://lovi.care/skincare/de/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- France: https://lovi.care/skincare/fr/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/missha/time-revolution-night-repair-ampoule/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule/for/combination-skin