# MISSHA Time Revolution Night Repair Ampoule Cream 5X for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [MISSHA](https://lovi.care/skincare/ie/brands/missha)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your combination skin, as niacinamide helps regulate oil production and strengthen the skin barrier, which is supportive for acne and blemishes.
- The presence of glycerin and bifida ferment lysate provides excellent hydration and enhances barrier resilience, contributing to overall skin health.
- The formulation is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/oily-acne-prone-skin): Average

## Key ingredients

Extreme Biome, Bifida Lysate Ferment, Niacinamide, Centella Asiatica Extract, Ceramide Np

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))

## What reviewers say

This anti-aging night cream is highly effective for dry and mature skin, providing deep hydration and plumping for a softer, glowing, and more elastic complexion. While many users appreciate its rich, nourishing texture and good value, some with oily or acne-prone skin find it too heavy and occasionally experience breakouts or a greasy finish.

- Liked: Deeply moisturizing (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Good value (sometimes noted)
- Liked: Rich consistency (sometimes noted)
- Disliked: Heavy or greasy (sometimes noted)
- Disliked: Fragrance sensitivity (rarely noted)
- Disliked: Packaging concerns (rarely noted)
- Disliked: Potential breakouts (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Missha Night Repair Ampoule Cream 5X work for acne-prone skin?

This cream works moderately well for acne-prone skin, as niacinamide helps control oil and strengthen the skin barrier while other ingredients provide good hydration without causing irritation. For this skin type, a product needs effective ingredients for blemishes, soothing extracts, and a light texture that balances oil without clogging pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for acne-prone skin?

Niacinamide helps regulate oil and strengthen the skin barrier, while glycerin and centella asiatica extract provide hydration and soothing care for acne-prone skin. To fit this skin type even better, an ideal product needs soothing extracts and ingredients that balance oil and moisture without feeling heavy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Extreme Biome do for acne-prone skin?

Extreme Biome is a poor fit for acne-prone skin because it lacks the specialized ingredients needed to clear pores and balance oil. A product of this type needs acne-fighting ingredients like salicylic acid or benzoyl peroxide, along with soothing agents, to calm breakouts and keep skin clear.
Sources: [Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/36350527/), [Journal of the European Academy of Dermatology and Venereology, 2025](https://pubmed.ncbi.nlm.nih.gov/39269130/)

### What does Bifida Ferment Lysate do for acne-prone skin?

Bifida Ferment Lysate helps acne-prone skin by calming redness and keeping the skin barrier strong. This ingredient may also support the skin's defenses against irritation, making it less likely to flare up.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### Where does this cream go in a skincare routine for acne-prone skin?

This moisturizing treatment goes in the evening routine after cleansing and a cleansing toner, right before your moisturizer. Acne-prone skin needs a product of this type that features soothing plant extracts and barrier-strengthening ingredients to help hydrate and calm blemishes without clogging pores.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first, letting it absorb, and then following with the cream to keep your skin calm and hydrated. A moisturizer with ceramides, niacinamide, and soothing plant extracts helps support your skin barrier and makes it easier to tolerate strong acne treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this cream?

You can use this moisturizing treatment twice a day as part of your routine. Daily application helps keep your skin hydrated and supports the skin barrier. Acne-prone skin works best with lightweight, oil-free hydrators and soothing ingredients like niacinamide and centella asiatica.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to cause major breakouts or purging for acne-prone skin, as it has a low risk of causing blemishes and lacks harsh ingredients that irritate the skin. To better care for acne-prone skin, this type of product needs lightweight hydrators like glycerin and soothing ingredients such as centella asiatica extract or niacinamide.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream around the eyes or on my body?

This moisturizing treatment can be used around the eyes or on the body, though acne-prone skin needs a lighter lotion with oil-controlling and soothing ingredients like salicylic acid or tea tree oil in those areas.

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ie/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.99 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ie/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — €14.07 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/ie/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — €35.01 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/ie/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.40 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ie/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.99 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/ie/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — €17.43 at Amazon

## Where to buy

- Amazon.ie: €26.80 (https://www.amazon.ie/dp/B09648RPKJ?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- Notino: €53.90 (https://www.notino.ie/missha/time-revolution-night-repair-ampoule-5x-intense-overnight-treatment-with-anti-ageing-effect/p-16145762/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Methyl Propanediol, Cyclohexasiloxane, Hydrogenated Polyisobutene, Caprylic Capric Triglyceride, Triethylhexanoin, Cetearyl Alcohol, Niacinamide, Dimethicone, 1,2-Hexanediol, Trehalose, Stearyl Alcohol, Beeswax, Cetyl Alcohol, Phytosteryl Isostearyl Cetyl Stearyl Behenyl Dimer Dilinoleate, Cetearyl Glucoside, Vinyl Dimethicone, Polyglyceryl-2 Stearate, Glyceryl Stearate, Palmitic Acid, Stearic Acid, Bergamot Oil Fruit, Hydroxyacetophenone, Dioscorea Japonica Root Extract, Ammonium Acryloyldimethyltaurate Vp Copolymer, Ethylhexylglycerin, Glycosyl Trehalose, Butylene Glycol, Alcohol, Bifida Lysate Ferment, Hydrogenated Hydrolysate Starch, Xanthan Gum, Adenosine, Raffinose, Glyceryl Polymethacrylate, Dextrin, Theobroma Cacao Shell Powder, Pelargonium Graveolens Oil Flower, Lecithin, Disodium Edta, Hydrogenated Lecithin, Camellia Sinensis Seed Oil, Argania Spinosa Kernel Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Helianthus Annuus Seed Oil Sunflower Seed Oil, Jojoba Seed Oil, Camellia Japonica Seed Oil, Macadamia Ternifolia Seed Oil, Glucose, Centella Asiatica Extract, Ficus Carica Fruit Extract, Polyquaternium-51, Cetearyl Olivate, Ceramide Np, Lavandula Angustifolia Oil Lavender Oil, Citrus Aurantium Dulcis Peel Oil, Sorbitan Olivate, Phellodendron Amurense Bark Extract, Lactobacillus Ferment, Myristic Acid, Lactobacillus Acerola Cherry Ferment, Lactococcus Ferment, Leuconostoc Radish Root Ferment Filtrate, Bifida Ferment Filtrate, Lactobacillus Soybean Extract Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Lactobacillus Lysate Ferment, Lactococcus Lysate Ferment, Monascus Extract, Sucrose Distearate, Rice Extract, Dipropylene Glycol, Biosaccharide Gum-1, Saccharomyces Ferment, Beta Vulgaris Root Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Brassica Oleracea Capitata Leaf Extract, Blueberry Fruit Extract, Solanum Melongena Fruit Extract, Anthemis Nobilis Oil Flower, Tocopherol, Sandalwood Oil, Bacillus Ferment
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin (this page)
- Germany: https://lovi.care/skincare/de/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-cream-5x/for/acne-prone-skin