# Medik8 Bakuchiol Peptides for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Medik8](https://lovi.care/skincare/ie/brands/medik8)
Category: [Serums and treatments](https://lovi.care/skincare/ie/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your acne, blemishes, and breakouts due to the presence of bakuchiol and Centella Asiatica Leaf Extract, which provide anti-inflammatory and skin-soothing properties, though it lacks sufficient ingredients for optimal oil control on your oily areas.
- The formula provides excellent anti-aging visible effects by minimizing fine lines and wrinkles with bakuchiol and undecylenoyl phenylalanine.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/sensitive-skin): Caution
- [Acne-prone skin](https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/oily-acne-prone-skin): Average

## Key ingredients

Bakuchiol, Peptides, Centella Asiatica Leaf Extract, Tocopherol, Moringa Oleifera Seed Oil

## What the research says

- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Asiatic acid-loaded solid lipid microparticles stabilized with poloxamer-188 reduced porphyrin intensity, enhanced skin barriers, and improved skin hydration and brightness in fifteen participants with mild-to-moderate acne. ([International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Emulgels containing Perilla frutescens seed oil, Moringa oleifera seed oil, and mixed seed oil microemulsions exhibit good stability, lack of cytotoxicity in PBMC, and no skin irritation or allergic reactions in human subjects. ([Polymers, 2022](https://pubmed.ncbi.nlm.nih.gov/35745923/))
- Topical application of a serum containing supramolecular Bakuchiol and Terminalia chebula extract significantly improved barrier function, reduced redness and sensitivity, and improved wrinkles and elasticity in 34 Chinese subjects with sensitive skin after 28 days. ([Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/))
- Bakuchiol functions as an anti-aging compound through retinol-like regulation of gene expression, producing significant improvements in lines, wrinkles, pigmentation, elasticity, firmness, and photo-damage after 12 weeks of twice-a-day facial application without usual retinol therapy-associated undesirable effects. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24471735/))
- A nature-based bakuchiol-containing cleanser and moisturizer improved visual and tactile smoothness, clarity, radiance, overall appearance, global anti-aging, and skin moisture content by 16% in 60 female subjects with sensitive mild to moderate photodamaged skin over 4 weeks. ([Journal of Drugs in Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33346506/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Moringa seed oil stimulated sebaceous lipogenesis, reduced pro-inflammatory cytokine secretion, and exhibited a low n-6/n-3 index in cultured human SZ95 sebocytes compared to untreated cells. ([International Journal of Molecular Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37373478/))
- Topical Moringa oleifera seed oil and its main constituent oleic acid reduced acute and chronic skin inflammation and epidermal hypertrophy in mice through glucocorticoid receptor activation without dexamethasone-like adverse effects on organ weights. ([Journal of Ethnopharmacology, 2020](https://pubmed.ncbi.nlm.nih.gov/32142866/))

## Why other serums fit acne-prone skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))

## What reviewers say

It is highly praised for its hydrating and plumping effects, leaving skin smooth and dewy. Some users note that anti-aging results are more subtle and take longer to appear compared to traditional Vitamin A products.

- Liked: Gentle retinol alternative (mostly mentioned)
- Liked: Hydrating and plumping (often mentioned)
- Liked: Luxurious texture (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Disliked: Slower results (sometimes noted)
- Disliked: High price (rarely noted)
- Disliked: Oily finish (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Medik8 Bakuchiol Peptides work for acne-prone skin?

Medik8 Bakuchiol Peptides offers moderate benefits for acne and breakouts by helping calm the skin, though an acne-prone skin type needs ingredients like niacinamide, zinc PCA, or propolis for better oil control and hydration.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this serum a good fit for acne-prone skin?

Medik8 Bakuchiol Peptides contains bakuchiol and Centella Asiatica Leaf Extract, which help soothe the skin and calm breakouts. To work best for acne-prone skin, this type of product also needs ingredients like niacinamide, zinc PCA, or propolis to control oil and balance oily areas.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does bakuchiol do for acne-prone skin?

Bakuchiol helps improve acne-prone skin by reducing pimples and dark spots left behind. It is unlikely to cause the heavy scaling and stinging often seen with traditional treatments, making it a gentle option for calming oily and sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/), [Journal of Drugs in Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33683079/)

### What do peptides do for acne-prone skin?

Peptides help acne-prone skin by calming redness, fighting breakout-causing bacteria, and supporting the skin barrier. These ingredients may also help reduce inflammation and soothe irritated skin with a low risk of side effects.
Sources: [Biochemical Pharmacology, 2025](https://pubmed.ncbi.nlm.nih.gov/39662606/), [Frontiers in Immunology, 2024](https://pubmed.ncbi.nlm.nih.gov/39744637/)

### Where does it go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Acne-prone skin also needs ingredients that help balance oil on oily areas.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol, applying it after your retinol once your skin is fully used to both. Because this product features soothing ingredients like bakuchiol and Centella Asiatica Leaf Extract, it may help keep your skin calm, but acne-prone skin also needs targeted ingredients for optimal oil control on oily areas.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/)

### How often should I use it?

You can use this treatment in the evening as part of your routine. An acne-prone skin type needs oil-controlling ingredients to keep shine and breakouts fully in check.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This treatment is unlikely to cause irritation or breakouts on your acne-prone skin because it has a very safe formula, though a product of this type needs stronger oil control ingredients to work best for oily areas.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/ie/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €14.94 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €52.57 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ie/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €185.00 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/ie/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.40 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ie/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.99 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ie/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.99 at Amazon

## Where to buy

- Lookfantastic: €50.60 (https://www.lookfantastic.ie/p/medik8-bakuchiol-peptides-30ml/12660650/)
- Notino: €66.50 (https://www.notino.ie/medik8/bakuchiol-peptides-anti-aging-and-anti-imperfection-serum/p-16156037/)
Prices checked 10 Oct – 14 Oct 2026.

## Ingredients

Caprylic Capric Triglyceride, Bakuchiol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Plukenetia Volubilis Seed Oil, Centella Asiatica Leaf Extract, Eclipta Prostrata Extract, Krameria Triandra Root Extract, Undecylenoyl Phenylalanine, Olea Europaea Oil Fruit Olive Oil Fruit, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Corallina Officinalis Extract, Coccinia Indica Fruit Extract, Moringa Oleifera Seed Oil, Tocopherol, Solanum Melongena Fruit Extract, Aloe Barbadensis Flower Extract, Jojoba Seed Oil, Curcuma Longa Root Extract, Ocimum Basilicum Leaf Extract Flower, Ocimum Sanctum Leaf Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medik8/bakuchiol-peptides/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medik8/bakuchiol-peptides/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/medik8/bakuchiol-peptides/for/acne-prone-skin (this page)
- Germany: https://lovi.care/skincare/de/p/medik8/bakuchiol-peptides/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/medik8/bakuchiol-peptides/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/medik8/bakuchiol-peptides/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/medik8/bakuchiol-peptides/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/medik8/bakuchiol-peptides/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/medik8/bakuchiol-peptides/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/medik8/bakuchiol-peptides/for/acne-prone-skin
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- Saudi Arabia: https://lovi.care/skincare/sa/p/medik8/bakuchiol-peptides/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medik8/bakuchiol-peptides/for/acne-prone-skin