MEDIHEAL AGE-R for acne-prone skin
Glutathione
Collagen
Peptides
Low
- AverageCombination Skin Fit
- AverageEffectiveness
- HighSafety
A weak match for acne-prone skin; the serums alongside fit it better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate anti-aging benefits for your combination skin, as collagen and peptides provide plumping and hydration, but lacks ingredients to address your acne and breakouts.
- While the formula is generally safe and free of harsh irritants for combination skin, it does not contain specialized ingredients like salicylic acid to target blemishes.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.4Overall rating based on 12.5k+ reviewsBased on a very large amount of data, users frequently achieve a 'glass skin' appearance and improved facial contouring, with many reporting enhanced product absorption and a more radiant complexion. While effective for dullness and mild sagging, results are highly dependent on consistent daily use, which some users find difficult to maintain. The device is also noted for improving skin texture and reducing pore visibility.
Highlights
Enhanced absorption Mostly Mentioned
- “products absorb instantly”
- “skincare feels supercharged”
- “no sticky residue left”
- “serums work better”
Glass skin glow Often Mentioned
- “skin looks dewy”
- “immediate glass skin”
- “glow lasts all day”
- “makeup sits better”
Time-consuming routine Often Mentioned
- “hard to stick to”
- “adds 10 mins to routine”
- “gave up after a month”
- “too much effort daily”
Improved texture Sometimes Noted
- “bumps smoothed out”
- “pores look smaller”
- “texture is softer”
- “makeup applies smoother”
Visible lifting Sometimes Noted
- “jawline looks snatched”
- “face feels tighter”
- “reduced morning puffiness”
- “cheekbones pop more”
High price point Sometimes Noted
- “very pricey investment”
- “gel is expensive”
- “not worth the full price”
- “wait for a sale”
Unpleasant sensation Sometimes Noted
- “zaps hurt sensitive areas”
- “teeth feel weird”
- “muscle twitching is creepy”
- “prickly sensation”
Potential irritation Rarely Noted
- “caused small bumps”
- “redness after use”
- “broke me out”
- “too harsh for sensitive skin”
Sources: lovi.care, medicube.us, amazon.com, youtube.com, reddit.com, cosmopolitan.com, and more
Questions and answers
Why is Mediheal AGE-R a weak match for acne-prone skin?
Mediheal AGE-R is a weak match for acne-prone skin because it offers hydration and plumping for aging but lacks ingredients like salicylic acid, niacinamide, or zinc PCA to target blemishes and control oiliness. A treatment for acne-prone skin needs blemish-fighting ingredients and balancing agents to keep the skin clear without causing excess oiliness.
Dermatology Practical & Conceptual, 2022Current Issues in Molecular Biology, 2024
Which ingredients make this cream a poor fit for acne-prone skin?
This cream is a weak match for acne-prone skin because it relies on glutathione, collagen, and peptides, which provide hydration and smoothing rather than targeting breakouts. A treatment for this skin needs ingredients like niacinamide, propolis, or zinc PCA to help clear blemishes and control oil while keeping skin balanced.
Dermatology Practical & Conceptual, 2022Current Issues in Molecular Biology, 2024
What does Glutathione do for acne-prone skin?
Glutathione helps protect acne-prone skin against everyday environmental stress and oxidation. This ingredient is unlikely to clear breakouts on its own, so acne-prone skin needs a product that also targets pores, calms redness, and balances oil with ingredients like salicylic acid or niacinamide.
Journal of the European Academy of Dermatology and Venereology, 2024
What does Collagen do for acne-prone skin?
Collagen does not directly target breakouts, but it helps keep dry or aging acne-prone skin soft and hydrated without clogging pores. Because this skin type often needs lightweight moisture and soothing care, a product of this type needs non-greasy hydrators and calming ingredients to support clear skin.
Current Issues in Molecular Biology, 2024Journal of Drugs in Dermatology, 2019
Where does this cream go in a skincare routine for acne-prone skin?
This treatment goes in the evening routine, as Lovi routines place treatments in the PM for simplicity and extra safety around sun exposure. Because it is a weak match that lacks ingredients to address acne and breakouts, acne-prone skin needs a product of this type that also includes blemish-targeting ingredients like salicylic acid.
Can I use it with retinol, and in what order?
You can use this treatment alongside retinol by applying your retinol first and following it with this product once it absorbs. This product is a weak match for your acne-prone skin because it lacks targeted blemish-fighting ingredients, so your routine for this skin type needs specialized ingredients like salicylic acid to properly clear breakouts.
How often should I use this cream?
This treatment fits your acne-prone skin poorly because it lacks ingredients to target breakouts. To properly care for acne-prone skin, a product of this type needs blemish-fighting ingredients like salicylic acid alongside its plumping and hydrating benefits.
Can it clog pores, cause breakouts or purging for acne-prone skin?
This treatment is unlikely to cause harsh irritation on acne-prone skin, but it lacks the specialized ingredients needed to actively address or prevent breakouts. A product of this type needs blemish-fighting ingredients like salicylic acid to properly care for acne-prone skin.
What the research says
Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen.
Dermatology Practical & Conceptual, 2022The use of cosmetic products containing collagen or its peptides improves the general condition of the skin, reduces wrinkle depth, improves hydration and density, reduces transepithelial water loss, and delays the aging process, while oral bioactive collagen peptides also reduce nail breakage.
Current Issues in Molecular Biology, 2024Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.
Advanced Science, 2025Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls.
Journal of the European Academy of Dermatology and Venereology, 2024Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2014Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity.
The Journal of Clinical and Aesthetic Dermatology, 2025Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023
Why other serums fit acne-prone skin better
Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris.
The Journal of Clinical and Aesthetic Dermatology, 2020A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Glutathione, Collagen, Peptides
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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