# Medicube Zero Pore One-Day Cream for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Medicube](https://lovi.care/skincare/ie/brands/medicube)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers excellent pore minimizing and skin smoothing for your oily skin due to the presence of salicylic acid and niacinamide, which decongest pores and even skin tone. Witch hazel extract and panthenol further support oil control and blemish reduction, making it highly suitable for acne-prone skin.
- The inclusion of Melaleuca Alternifolia tree leaf extract and Vitis Vinifera fruit extract provides additional antioxidant and soothing benefits, complementing the primary active ingredients.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Panthenol, Bha, Glycerin, Niacinamide, Sodium Hyaluronate

## What the research says

- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Topical application of 100% tea tree oil significantly reduced histamine-induced mean weal volume compared to control in twenty-seven volunteers. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/))
- Topical 5% tea tree oil gel significantly improved total acne lesions and acne severity index compared to placebo in 60 patients with mild to moderate acne vulgaris, showing 3.55 times and 5.75 times greater efficacy respectively. ([Indian Journal of Dermatology, Venereology and Leprology, 2007](https://pubmed.ncbi.nlm.nih.gov/17314442/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients. ([Journal of the American Academy of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20488582/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users with oily and combination skin appreciate this cream's lightweight, non-sticky texture that effectively balances moisture and controls sebum. Many report smoother skin texture and a reduction in the appearance of pores over time, though some find the "one-day" pore-shrinking claims to be exaggerated, suggesting it functions better as a daily moisturizer than a rapid treatment.

- Liked: Lightweight texture (often mentioned)
- Disliked: Strong fragrance (often mentioned)
- Liked: Oil control (sometimes noted)
- Liked: Skin smoothing (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Unsanitary packaging (sometimes noted)
- Liked: Pore maintenance (rarely noted)
- Disliked: Potential irritation (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes the Zero Pore One-Day Cream a great fit for oily acne-prone skin?

The Zero Pore One-Day Cream is a great fit because salicylic acid and niacinamide decongest pores and smooth your skin while witch hazel and panthenol help control oil and reduce blemishes. It also includes soothing tea tree leaf extract and grape extract, and it is safe and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Salicylic acid and niacinamide make this cream a great fit for your oily skin by clearing out pores and evening out skin tone. Witch hazel extract and panthenol further help control oil and calm blemishes.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### What does Panthenol do for oily acne-prone skin?

Panthenol helps regulate sebum, improves skin hydration, and reduces redness and irritation in oily acne-prone skin. It is well tolerated and may support barrier recovery without causing adverse reactions.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/)

### What does Bha do for oily acne-prone skin?

BHA helps clear breakouts and keeps oily acne-prone skin balanced by gently clearing out pores and reducing skin oiliness. It is unlikely to cause irritation and may also improve overall skin hydration and texture.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing, and you can follow it with a moisturizer. It helps decongest pores, smooth skin, and reduce blemishes without irritating your skin.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it first helps soothe the skin and keeps it feeling comfortable while using stronger treatments. This type of moisturizer is unlikely to cause irritation when paired with active ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this cream?

This cream is great for your oily acne-prone skin and fits into your evening routine as a treatment step. You can start using it once a week, and if your skin handles it well, you may carefully use it more often.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is a great fit for oily acne-prone skin and helps clear pores and smooth skin without causing irritation. Salicylic acid and niacinamide work to keep pores clear and control oil, while soothing ingredients keep your skin calm.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### Can I use this cream around the eyes or on my body?

This cream is generally safe to use on the body, but it is best to avoid the very thin skin right around your eyes. Clinical studies show that skin thickness varies significantly across the body, with the eyelids being among the thinnest areas where potent active ingredients may cause unwanted sensitivity.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ie/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — €14.07 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ie/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — €18.99 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ie/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — €37.20 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — €95.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ie/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ie/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-acne-prone-skin) — Superior fit — €15.64 at Amazon

## Where to buy

- Amazon.ie: €21.50 (https://www.amazon.ie/dp/B0DVN7TWPR?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- Notino: €24.90 (https://www.notino.ie/medicube/zero-pore-one-day-cream-light-moisturizing-cream-to-tighten-pores/p-16299752/)
Prices checked 13 Oct – 5 Nov 2026.

## Ingredients

Water, Glycerin, Witch Hazel Extract, Panthenol, Allantoin, Melaleuca Alternifolia Tree Leaf Extract, Butylene Glycol, 12-Hexanediol, Hyaluronic Acid, Salicylic Acid, Niacinamide, Vitis Vinifera Fruit Extract Grape Fruit Extract, Camellia Sinensis Leaf Extract, Peptides, Sorbitan Olivate, Beta-Glucan
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/zero-pore-one-day-cream/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/zero-pore-one-day-cream/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/oily-acne-prone-skin (this page)
- Germany: https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-cream/for/oily-acne-prone-skin
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