# Medicube Collagen Niacinamide Jelly Cream for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Medicube](https://lovi.care/skincare/ie/brands/medicube)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your combination skin as niacinamide helps regulate sebum and reduce inflammation, while trehalose provides essential hydration. Collagen and its derivatives further support skin smoothing and texture refinement, addressing your concerns about acne and breakouts.
- The inclusion of various botanical extracts and humectants offers additional soothing and moisturizing benefits, complementing the primary active ingredients.
- The product is safe for your skin, containing no harsh ingredients and featuring soothing components like niacinamide and trehalose.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Collagen, Niacinamide, Hydrolyzed Collagen, Water-Soluble Collagen, Squalane

## What the research says

- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Based on a very large amount of data, this moisturizer is highly regarded for providing an immediate radiant glow and significant hydration, attributed to its unique cooling jelly texture. Some users find the finish to be sticky or tacky, and a portion of reviews suggest it performs better as a night mask compared to a daytime product.

- Liked: Glass skin glow (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Disliked: Sticky/tacky finish (often mentioned)
- Liked: Cooling jelly texture (sometimes noted)
- Liked: Plumping/firming (sometimes noted)
- Disliked: Absorption issues (sometimes noted)
- Disliked: Breakouts/irritation (rarely noted)
- Disliked: Fragrance/scent (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Medicube Collagen Niacinamide Jelly Cream a great fit for acne-prone skin?

This cream is a great fit for your acne-prone skin because niacinamide helps balance oil and calm redness while trehalose delivers deep hydration. Collagen and plant extracts further smooth your skin texture and soothe breakouts without harsh ingredients.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/)

### Which ingredients make this cream a good fit for acne-prone skin?

This cream is a great fit for acne-prone skin because niacinamide helps balance oil and calm redness, while trehalose provides lightweight hydration. Additionally, collagen and its derivatives work to smooth texture and help keep breakouts under control.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/)

### What does Collagen do for acne-prone skin?

Collagen does not directly target breakouts, but it helps keep dry or aging acne-prone skin soft and hydrated without clogging pores. Because this skin type often needs lightweight moisture and soothing care, a product of this type needs non-greasy hydrators and calming ingredients to support clear skin.
Sources: [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/), [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30681787/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this cream go in a skincare routine for acne-prone skin?

This cream goes in your morning routine after a hydrating toner and before your SPF, and in your evening routine as the final moisturizing step after your treatment. It is a great fit for acne-prone skin because niacinamide helps regulate oil and reduce inflammation while trehalose provides hydration.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol to keep your skin calm and hydrated while helping reduce breakouts. Apply your retinol first, let it absorb, and then smooth on this moisturizer to help lower the chances of dryness or irritation.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/), [The Journal of Dermatological Treatment, 2016](https://pubmed.ncbi.nlm.nih.gov/26293170/)

### How often should I use this cream?

You can use this cream daily as part of your morning and evening routine. Regular use helps keep acne-prone skin calm and hydrated while supporting smoother texture.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is a great fit and is unlikely to cause breakouts on acne-prone skin, as niacinamide helps calm redness and manage oil while trehalose adds lightweight hydration.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/)

### Can I use this cream around the eyes or on my body?

Yes, you can use this moisturizing treatment around the eyes and on the body because it has a very safe profile and lacks harsh ingredients. It helps keep thin or body skin calm and smooth while providing gentle hydration.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ie/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.99 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ie/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — €14.07 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/ie/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — €35.01 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/ie/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.40 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ie/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.99 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/ie/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — €17.43 at Amazon

## Where to buy

- Amazon.ie: €21.99 (https://www.amazon.ie/dp/B0CM2PPNMW?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- Notino: €15.50 (https://www.notino.ie/medicube/collagen-jelly-cream-intensive-gel-cream-with-collagen/p-16329860/)
- Lookfantastic: €23.25 (https://www.lookfantastic.ie/p/medicube-collagen-jelly-cream-110ml/16858534/)
Prices checked 10 Oct – 4 Nov 2026.

## Ingredients

Water, Propanediol, Dipropylene Glycol, Butylene Glycol, Methylpropanediol, Diethoxyethyl Succinate, Ethoxydiglycol, Ammonium Acryloyldimethyltaurate Beheneth-25 Methacrylate Crosspolymer, Niacinamide, Trehalose, 1,2-Hexanediol, Chlorella Vulgaris Extract, Collagen, Hydrolyzed Collagen, Cynanchum Atratum Extract, Althaea Rosea Flower Extract, Water-Soluble Collagen, Allium Sativum Bulb Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Bertholletia Excelsa Seed Extract, Brassica Oleracea Italica Extract, Camellia Sinensis Seed Extract, Salmon Egg Extract, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Spinach Leaf Extract, Blueberry Fruit Extract, Wine Extract, Polyglyceryl-10 Isostearate, Tromethamine, Glucose, Polyglyceryl-10 Oleate, Ethylhexylglycerin, Fructooligosaccharides, Fructose, Adenosine, Sodium Phytate, Cyanocobalamin, Tocopherol, Pullulan, Glycerin, Hydroxypropyltrimonium Hyaluronate, Squalane, Soluble Proteoglycan, Hydrolyzed Elastin, Sodium Dna, Carbomer, Xanthan Gum, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin (this page)
- Germany: https://lovi.care/skincare/de/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin