La Prairie Skin Caviar Luxe Cream for mature skin

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Questions and answers

What the research says

• Retinyl palmitate-loaded non-ionic lamellar liquid crystalline systems provided a significant reduction of orbicular wrinkles in human volunteers compared to systems without retinyl palmitate.

  Colloids and Surfaces. B, Biointerfaces, 2011

• A vitamin A palmitate and antioxidant-containing oil-based moisturizer improved fine lines, wrinkles, pigmentation, tone, texture, dryness, firmness, and clarity across various body sites compared to a no-treatment group over 12 weeks.

  Journal of Cosmetic Dermatology, 2013

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• A mixture of Panax ginseng and Crataegus pinnatifida prevented skin aging by improving procollagen type I expression, diminishing matrix metalloproteinase-1 secretion, reducing skin roughness and photodamage scores, and decreasing loss of skin moisture in human dermal fibroblasts and healthy human skin.

  Journal of Ginseng Research, 2017

• Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline.

  In Vivo, 2023

• Polyvinyl alcohol/carboxymethyl chitosan hydrogels loaded with 5% caviar extract significantly increased CK-18 levels and pan-CK expression in adipose-derived mesenchymal stem cells compared to lower concentrations and controls.

  Tissue Engineering. Part A, 2026

• Caviar extract inhibits UV-induced skin photoaging by reducing NF-κB, MMP-3, and MMP-9 expression, increasing IκB, TIMP-1, SOD, HYP, COL17A1, KRT10, and KRT14 levels, and exhibiting antioxidant activity in HaCaT cells and a skin aging mice model.

  Photochemistry and Photobiology, 2025

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects.

  Rejuvenation Research, 2015

• A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects.

  Journal of Ginseng Research, 2022

• A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline.

  Journal of Toxicology and Environmental Health. Part A, 2020

• Topical formulations containing DNA repair enzymes or RNA fragments reduced UV-induced contact hypersensitivity suppression to 19% and 7% respectively compared to 64% in unprotected subjects, and decreased thymine dimers by 18% in humans.

  Photochemistry and Photobiology, 2008

• Chemically modified mRNA encoding epidermal growth factor (EGF cmRNA) significantly accelerated wound healing, promoted cell proliferation and migration in vitro, and outperformed recombinant human EGF by Day 14 in a full-thickness skin defect mouse model.

  International Wound Journal, 2025

• Transient correction of COL7A1 mutations using a non-viral 3'-RTMS6m repair molecule achieved a trans-splicing efficiency of ~1.5% in keratinocytes and ~0.6% in fibroblasts, with restored type VII collagen protein expression in vitro and accumulation within the basement membrane zone of RDEB skin equivalents.

  International Journal of Molecular Sciences, 2023

• Topical application of photolyase-containing liposomes followed by photoreactivating light decreased UVB-induced dimers by 40-45% and prevented immunosuppression, erythema, and sunburn-cell formation in healthy human subjects.

  Proceedings of the National Academy of Sciences of the United States of America, 2000

• Topical application of photolyase plus sunscreen significantly reduced the formation of CPDs and apoptotic cell death compared to sunscreen alone in ten human volunteers.

  Molecular Medicine Reports, 2012

• Topical application of water-in-oil nanoemulsions containing plasmid DNA on murine skin facilitated transfection primarily in follicular keratinocytes with optimal transgene expression at 24 hours, outperforming cationic liposome controls.

  International Journal of Pharmaceutics, 2001

Ingredients

Water, Dimethicone, Cetearyl Alcohol, Butyrospermum Parkii Butter Shea Butter, Glycerin, Prunus Amygdalus Dulcis Oil, Butylene Glycol, Cetearyl Glucoside, Octyldodecanol, Glyceryl Stearate, Glycoproteins, Panax Ginseng Root Extract, Equisetum Arvense Extract, Caviar Extract, Tocopheryl Acetate, Pullulan, Mangifera Indica Seed Oil, Astaxanthin Extract, Lactic Acid, Caulerpa Lentillifera Extract, Sodium Dna, Ceramide Np, Lecithin, Tocopherol, Sodium Hyaluronate, Diethylhexyl Syringylidenemalonate, Carnosine, Rna, Hydrolyzed Rice Bran Protein, Hydrogenated Lecithin, Borago Officinalis Seed Oil, Citric Acid, Malic Acid, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Lactobacillus Ferment, Polyglucuronic Acid, Retinyl Palmitate, Yeast Extract, Tetrapeptide-3, Ascorbyl Palmitate, Glycine Soja Oil Soybean Oil, Silybum Marianum Fruit Extract, Biotin, Propylheptyl Caprylate, Sodium Methyl Stearoyl Taurate, Polyacrylate Crosspolymer-6, Cetearyl Dimethicone Crosspolymer, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Ethylhexylglycerin, Alcohol, Xanthan Gum, Sodium Hydroxide, Disodium Edta, Mica, Polyglyceryl-10 Stearate, Sorbitan Isostearate, Polysorbate 60, Propylene Glycol, Caprylic Capric Triglyceride, Sucrose Stearate, Sodium Oleate, Parfum, Linalool, Citronellol, Geraniol, Limonene, Alpha-Isomethyl Ionone, Benzyl Salicylate, Phenoxyethanol, Sodium Dehydroacetate, Potassium Sorbate, Titanium Dioxide Ci 77891, Iron Oxides Ci 77491, Yellow 5 Ci 19140, Red 4 Ci 14700, Ci 15985

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.