# HydroPeptide Power Serum for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [HydroPeptide](https://lovi.care/skincare/ie/brands/hydropeptide)
Category: [Serums and treatments](https://lovi.care/skincare/ie/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Excellent for your normal skin, this serum utilizes multiple peptides like Hexapeptide-11 and Palmitoyl Tripeptide-5 to effectively firm and reduce wrinkles by stimulating collagen production.
- Glycerin and Sodium Hyaluronate provide essential hydration, while Tetrahexyldecyl Ascorbate offers antioxidant protection, further supporting skin elasticity and a healthy appearance.
- The formula is safe for your skin, containing soothing ingredients like Tocopherol and Glycerin with no harsh or prohibited substances.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/oily-acne-prone-skin): High

## Key ingredients

Palmitoyl Tripeptide-5, Hexapeptide-11, Acetyl Hexapeptide-30, Sodium Hyaluronate, Lemon Peel Extract

## What the research says

- Hexapeptide-11 activated proteasome, autophagy, chaperones, and antioxidant response genes, protected fibroblasts against oxidative-stress-mediated premature cellular senescence, and improved skin elasticity in human subjects. ([Redox Biology, 2015](https://pubmed.ncbi.nlm.nih.gov/25974626/))
- Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects. ([Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Hexapeptide-11 reversibly downregulated ATM and p53 protein expression in intrinsically aged fibroblasts, extrinsically aged fibroblasts, and extrinsically aged dermal papillae cells at concentrations between 0.1% and 1.0% in vitro, thereby influencing the onset of cellular senescence. ([Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23578831/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users consistently praise this serum as a lightweight, non-greasy anti-aging powerhouse that visibly plumps and smooths the skin. While it is highly effective for hydrating dry skin and softening fine lines without irritating sensitive complexions, the high price point and distinct scent are occasional points of contention.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Visible anti-aging (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Liked: Pleasant scent (sometimes noted)
- Disliked: Packaging size (rarely noted)
- Disliked: Scent dislike (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes HydroPeptide Power Serum a great fit for mature skin?

This serum is a great fit because it uses multiple peptides like Palmitoyl Tripeptide-5 and Hexapeptide-11 to help firm and smooth out wrinkles. It also includes sodium hyaluronate and glycerin to provide deep hydration while antioxidant vitamin C supports overall elasticity.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/), [Redox Biology, 2015](https://pubmed.ncbi.nlm.nih.gov/25974626/)

### Which ingredients make this serum a good fit for mature skin?

This serum is a great fit for mature skin because it uses multiple peptides like Hexapeptide-11 and Palmitoyl Tripeptide-5 to help firm and reduce wrinkles by encouraging collagen production. Glycerin and Sodium Hyaluronate also provide essential hydration, while Tetrahexyldecyl Ascorbate offers antioxidant protection to support skin elasticity and a healthy look.
Sources: [Redox Biology, 2015](https://pubmed.ncbi.nlm.nih.gov/25974626/), [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### What does Palmitoyl Tripeptide-5 do for mature skin?

Palmitoyl tripeptide-5 helps improve firmness, smoothness, and overall youthful appearance on mature skin. It may also boost moisture and reduce the look of fine lines and wrinkles.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### What does Hexapeptide-11 do for mature skin?

Hexapeptide-11 helps improve skin firmness and elasticity in mature skin by supporting collagen production and defending cells against oxidative stress. This ingredient protects against premature aging and helps keep the skin looking smooth and youthful.
Sources: [Redox Biology, 2015](https://pubmed.ncbi.nlm.nih.gov/25974626/), [Skin Pharmacology and Physiology, 2021](https://pubmed.ncbi.nlm.nih.gov/33849044/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, following Lovi's guidance for safe and simple active ingredient use.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to clean skin and letting it absorb before layering your retinol product. This helps firm and hydrate your skin while minimizing potential dryness or irritation from the retinol.
Sources: [Redox Biology, 2015](https://pubmed.ncbi.nlm.nih.gov/25974626/)

### How often should I use this serum?

This serum is used in your evening routine, applied after cleansing and toning and before moisturizing. Using it at night keeps things simple and provides extra safety around sun exposure, though some serums can also be used in the morning or twice a day.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts for mature skin because it features a safe formula with soothing ingredients and no harsh substances. It helps keep your skin smooth and hydrated while improving firmness without causing irritation.
Sources: [Redox Biology, 2015](https://pubmed.ncbi.nlm.nih.gov/25974626/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ie/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €185.00 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €31.40 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/ie/p/augustinus-bader/the-serum/for/mature-skin) — High fit — €385.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ie/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €56.86 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ie/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €14.28 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/ie/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €50.82 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Butylene Glycol, Propanediol, Diethylhexyl Carbonate, Isopentyldiol, Pentylene Glycol, Diheptyl Succinate, Caprylyl Glycol, Hydroxyacetophenone, Olea Europaea Fruit Olive Fruit, Sodium Stearoyl Glutamate, Cetearyl Alcohol, Glyceryl Stearate, Potassium Olivoyl Hydrolyzed Oat Protein, Lysolecithin, Sclerotium Gum, Hexapeptide-11, Tetrahexyldecyl Ascorbate, 1,2-Hexanediol, Capryloyl Glycerin Sebacic Acid Copolymer, Phenylpropanol, Sorbitan Laurate, Pullulan, Xanthan Gum, Caprylic Capric Triglyceride, Glyceryl Oleate, Glycine Soja Seed Extract Soybean Seed Extract, Anogeissus Leiocarpus Bark Extract, Lemon Peel Extract, Palmitoyl Hexapeptide-19, Sodium Phytate, Hydroxyethylcellulose, Sodium Hyaluronate, Acetyl Dipeptide-1 Cetyl Ester, Citrus Aurantium Dulcis Peel Extract, Grapefruit Fruit Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Bergamot Fruit Extract, Citrus Aurantifolia Peel Extract, Citrus Nobilis Fruit Extract Mandarin Orange Fruit Extract, Tangerine Peel Extract, Acetyl Hexapeptide-30, Barosma Betulina Leaf Extract, Vanilla Planifolia Fruit Extract, Vitis Vinifera Fruit Extract Grape Fruit Extract, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/hydropeptide/power-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/hydropeptide/power-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/mature-skin (this page)
- Germany: https://lovi.care/skincare/de/p/hydropeptide/power-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/hydropeptide/power-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/hydropeptide/power-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/hydropeptide/power-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/hydropeptide/power-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/hydropeptide/power-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/hydropeptide/power-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/hydropeptide/power-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/hydropeptide/power-serum/for/mature-skin