# Good Molecules Super Peptide Serum for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Good Molecules](https://lovi.care/skincare/ie/brands/good-molecules)
Category: [Serums and treatments](https://lovi.care/skincare/ie/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for sensitive skin.

## Why this fit

- Offers moderate plumping for normal skin due to peptides like Acetyl Hexapeptide-8 and Acetyl Octapeptide-3, which support improving volume and elasticity.
- Glycerin and Sodium Hyaluronate provide humectant action, offering general hydration and soothing benefits that are supportive but not directly targeted at your redness and irritation.
- The absence of harsh ingredients ensures no risks of irritation for your sensitive skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Copper Tripeptide-1, Sodium Hyaluronate, Glycerin

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model. ([International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Users consistently praise this serum for its ability to plump and hydrate the skin, with many noting a visible reduction in fine lines and improved skin texture over time. While most find it gentle and effective for the price, some users with sensitive skin noted the bergamot scent, and others felt it required long-term use to see significant anti-aging results.

- Liked: Great value (mostly mentioned)
- Liked: Plumps and hydrates (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Liked: Gentle formula (sometimes noted)
- Disliked: Scent complaints (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: No visible change (rarely noted)
- Disliked: Soapy texture (rarely noted)
- Disliked: Watery consistency (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Super Peptide Serum a great fit for sensitive skin?

Good Molecules Super Peptide Serum is a great fit for sensitive skin because it lacks harsh ingredients, ensuring a very low risk of irritation. Its blend of glycerin and sodium hyaluronate also provides soothing benefits and helps keep skin hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it lacks harsh ingredients that could cause irritation. It also features glycerin and sodium hyaluronate to provide gentle hydration and comfort.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Argireline do for sensitive skin?

Argireline is unlikely to cause irritation and is sometimes found in products designed to calm reactive skin. Studies show it helps smooth the look of wrinkles and decrease skin roughness when used consistently.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Pharmaceuticals, 2021](https://pubmed.ncbi.nlm.nih.gov/34451799/)

### What does Acetyl Octapeptide-3 do for sensitive skin?

Acetyl Octapeptide-3 is unlikely to irritate sensitive skin and may help soften expression lines by relaxing facial tension. To care for sensitive skin properly, this type of product needs soothing ingredients and a gentle, fragrance-free formula to keep your face calm and smooth.

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine, after your soothing toner and before your moisturizer. Using treatments at night helps keep your routine simple and adds extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to give your skin a boost of hydration, followed by your retinol. The gentle formula of this serum is unlikely to cause irritation when paired with stronger products like retinoids.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

Use this serum in your evening routine, applying it once a day. Glycerin and sodium hyaluronate help keep skin hydrated while peptides support firmness with a low risk of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts or purging for sensitive skin. The formula avoids heavy, pore-clogging ingredients and features gentle hydrators that help keep skin soft and calm without irritation.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ie/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €185.00 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €29.07 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ie/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — €22.51 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ie/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — €56.86 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/ie/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €21.81 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/ie/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €39.35 at Amazon

## Where to buy

- Amazon.ie: €24.66 (https://www.amazon.ie/dp/B091MTKS35?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Propanediol, Glycerin, 1,2-Hexanediol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Copper Tripeptide-1, Ethylhexylglycerin, Caprylyl Glycol, Glycine, Sodium Hyaluronate, Xanthan Gum, Ammonium Acryloyldimethyltaurate Vp Copolymer, Diheptyl Succinate, Capryloyl Glycerin Sebacic Acid Copolymer, Chlorphenesin, Disodium Edta, Butylene Glycol, Glycereth-25 Pca Isostearate, Bht, Phenoxyethanol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sorbitan Isostearate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Tromethamine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/super-peptide-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/super-peptide-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/good-molecules/super-peptide-serum/for/sensitive-skin (this page)
- Germany: https://lovi.care/skincare/de/p/good-molecules/super-peptide-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/good-molecules/super-peptide-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/good-molecules/super-peptide-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/good-molecules/super-peptide-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/good-molecules/super-peptide-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/good-molecules/super-peptide-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/good-molecules/super-peptide-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/good-molecules/super-peptide-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/good-molecules/super-peptide-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/good-molecules/super-peptide-serum/for/sensitive-skin