# Good Molecules 5% Niacinamide Serum with Ectoin for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Good Molecules](https://lovi.care/skincare/ie/brands/good-molecules)
Category: [Serums and treatments](https://lovi.care/skincare/ie/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate skin tone evening and barrier resilience for your oily skin, as niacinamide and ectoin help regulate oil and repair the skin barrier. Glycerin and propanediol provide supportive hydration beneficial for acne and breakouts.
- The formula is highly suitable for oily skin due to the presence of niacinamide for seboregulation and ectoin for barrier repair.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Niacinamide, Ectoin, Glycerin

## What the research says

- A mixture of propanediol, xylitol, and caprylic acid demonstrated in vitro antimicrobial activity against C. acnes and S. aureus, reduced 5-alpha reductase expression, and decreased skin oiliness, porphyrin, and inflammatory lesions in participants over 28 days. ([Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Combining ectoine and mannitol with UV filters significantly improved protection of squalene oxidation, catalase activity, and trans-UCA compared to UV filters alone in 10 subjects on irradiated areas. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37539499/))
- Topical 7% ectoine during serial 1064-nm Nd:YAG laser therapy produced a greater reduction in skin erythema, improved stratum corneum hydration, reduced transepidermal water loss, and decreased low-echogenic pixels in thirty participants compared to a vehicle control. ([Biomedicines, 2026](https://pubmed.ncbi.nlm.nih.gov/42792808/))
- Regular application of a novel anti-ageing cream containing hyaluronic acid, ectoin, and botanical actives significantly reduced wrinkle depth and length in the periorbital area while demonstrating very good skin tolerance. ([Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on limited data, this serum is highly regarded as a gentle and hydrating option, particularly suitable for sensitive or reactive skin. Users frequently report improvements in skin texture, a reduction in redness, and minimized pores. The inclusion of Ectoin is noted for providing a plump and hydrated feel without the irritation sometimes associated with higher concentrations of niacinamide.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Gentle & non-irritating (often mentioned)
- Liked: Hydrating & plumping (often mentioned)
- Liked: Improves texture & pores (sometimes noted)
- Disliked: Slight stickiness (sometimes noted)
- Disliked: Breakouts (rarely noted)
- Disliked: Immediate irritation (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Good Molecules 5% Niacinamide Serum with Ectoin work for oily acne-prone skin?

This serum works moderately well for oily acne-prone skin, as niacinamide and ectoin help control oil and repair the skin barrier while glycerin and propanediol provide light hydration. It has a very safe formula with little risk of irritation, though top-rated treatments for this skin type tend to include potent blemish-fighting extracts and antioxidants like Vitamin C or propolis.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide and ectoin make this serum a good fit for your oily acne-prone skin because they help control oil and repair the skin barrier. Glycerin and propanediol also provide light hydration that is helpful for breakouts. A treatment for this skin needs balancing ingredients like vitamin C or propolis and soothing extracts to control excess oil while keeping the face comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### What does Ectoin do for oily acne-prone skin?

Ectoin helps protect oily acne-prone skin from sun damage and premature aging caused by UV rays. It is lightweight and unlikely to clog pores, making it a comfortable addition to your daily routine.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37539499/), [Skin Pharmacology and Physiology, 2004](https://pubmed.ncbi.nlm.nih.gov/15452409/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing, which keeps the routine simple and protects the skin around sun exposure. This type of skin needs oil-balancing niacinamide, barrier-repairing ectoin, and lightweight hydrators like glycerin.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to help keep your skin calm and hydrated, followed by retinol. This product is unlikely to cause irritation because it leaves out harsh ingredients and includes soothing components. Oily acne-prone skin of this type needs lightweight hydrators and oil-regulating ingredients like niacinamide and ectoin.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

You can use this treatment in the evening to keep things simple and safe around sun exposure, though some serums can also be used in the morning or twice a day. It is gentle on oily acne-prone skin and unlikely to cause irritation.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to cause breakouts on oily skin, as it has a very safe formula with soothing ingredients and no harsh components. However, because this is only an average fit for your skin, an ideal product for you needs oil-controlling ingredients like niacinamide alongside lightweight hydration to keep pores clear.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/ie/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — €14.94 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €29.07 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €31.40 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — €95.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ie/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ie/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — €16.50 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Water, Niacinamide, Glycerin, Propanediol, Ectoin, 1,2-Hexanediol, Caprylyl Glycol, Xanthan Gum, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/5-niacinamide-serum-with-ectoin/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/5-niacinamide-serum-with-ectoin/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/good-molecules/5-niacinamide-serum-with-ectoin/for/oily-acne-prone-skin (this page)
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