Dermol 500 Lotion for dry skin
Benzalkonium Chloride
Chlorhexidine Dihydrochloride
Liquid Paraffin
Isopropyl Myristate
Cetostearyl AlcoholAverage
- AverageDry Skin Fit
- AverageEffectiveness
- HighSafety
Works for dry skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your dry skin due to liquid paraffin and isopropyl myristate, which provide emollient benefits by hydrating the skin.
- While it offers general skincare benefits, it lacks sufficient humectants for optimal hydration, which is a key concern for your dry or flaky skin.
- The product is safe for your dry skin as it contains no prohibited or harsh ingredients that could cause irritation.
How to apply
- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
People Say
★4.9Overall rating based on 1000+ reviewsIt is celebrated for its versatility as both a leave-on moisturizer and a soap substitute, providing rapid relief from itching and preventing secondary infections due to its antimicrobial properties.
Highlights
Versatile application Mostly Mentioned
- “Soap substitute”
- “shower gel”
- “leave-on moisturizer”
Excellent texture Often Mentioned
- “Non-greasy”
- “absorbs quickly”
- “light consistency”
Hand care Often Mentioned
- “Heals cracked hands”
- “non-drying wash”
- “gentle cleanser”
Rapid itch relief Often Mentioned
- “Soothes irritation”
- “stops scratching”
- “calms redness”
Antimicrobial benefits Sometimes Noted
- “Prevents infection”
- “clears folliculitis”
- “kills bacteria”
Adverse reactions Rarely Noted
- “Facial rash”
- “stinging sensation”
- “increased redness”
Insufficient for dryness Rarely Noted
- “Too thin”
- “not rich enough”
- “requires thicker cream”
Medicinal scent Rarely Noted
- “Weird smell”
- “chemical odor”
- “unpleasant scent”
Packaging issues Rarely Noted
- “Pump faults”
- “hard to empty”
- “broken dispenser”
Texture dislike Rarely Noted
- “Too runny”
- “watery consistency”
- “not lotion-like”
Sources: lovi.care, pharmica.co.uk, medino.com, chemist-4-u.com, amazon.com, chemistdirect.co.uk, and more
Questions and answers
How well does Dermol 500 Lotion work for dry skin?
Dermol 500 Lotion works moderately well for dry skin, helping to keep it soft and comfortable with ingredients like liquid paraffin and isopropyl myristate. However, it lacks sufficient water-attracting humectants for optimal hydration. A moisturizing treatment for dry skin needs a rich blend of hydrating and barrier-repairing ingredients like ceramides and glycerin to fully address dryness.
Which ingredients make this lotion a good fit for dry skin?
Liquid paraffin and isopropyl myristate make this lotion a good fit for dry skin by providing moderate moisture and helping keep the skin soft. However, this skin type needs products with rich hydrating ingredients like glycerin, sodium hyaluronate, and essential ceramides to achieve optimal hydration.
What does Benzalkonium Chloride do for dry skin?
Benzalkonium chloride is not a good fit for dry skin because it can weaken the skin barrier and cause irritation or allergic reactions, especially on compromised skin. Products for dry skin need nourishing, hydrating ingredients like ceramides, glycerin, and natural oils to soothe dryness and restore a soft, smooth feeling.
What does Chlorhexidine Dihydrochloride do for dry skin?
Chlorhexidine dihydrochloride is an antiseptic that is unlikely to directly benefit dry skin and may cause irritation or increased dryness with frequent use. When caring for dry skin, it is best to focus on gentle, hydrating ingredients that support the skin barrier rather than strong antiseptics.
Where does it go in a skincare routine for dry skin?
Dermol Dermol 500 Lotion works as a moisturizing treatment in your daily routine, fitting into the morning after your hydrating toner and in the evening after your cleanser and any treatment. Because dry skin needs extra moisture, a product of this type needs richer hydrating ingredients like humectants to keep skin soft and smooth.
Can I use this lotion with retinol, and in what order?
You can use this lotion with retinol by applying it after your retinol treatment to help soothe your skin and lock in moisture. This product provides moderate hydration with liquid paraffin and isopropyl myristate, but dry skin needs extra ingredients like humectants for optimal hydration.
How often should I use it?
You can use Dermol Dermol 500 Lotion daily to help keep your dry skin soft and smooth. Regular daily application of this type of moisturizer is unlikely to cause irritation while supporting your skin barrier, though dry skin generally needs extra water-attracting ingredients for optimal hydration.
Can this lotion clog pores, cause breakouts or purging for dry skin?
This lotion is unlikely to cause breakouts or clog pores on dry skin, as its ingredients have a good safety profile and do not include harsh substances. However, dry skin needing a better fit requires ingredients like humectants to lock in moisture and keep flaky areas smooth.
Can I use it around the eyes or on my body?
You can use this lotion on your body, but it is not specifically formulated for the thin skin around the eyes. While it helps soften and hydrate dry areas safely, dry skin of this type needs products containing strong water-holding ingredients like glycerin or hyaluronic acid for optimal hydration.
Is this lotion fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016Topical application of an intimate cleansing gel containing chlorhexidine, hyaluronic acid, and anti-inflammatory agents after ultrasound scalpel-assisted hemorrhoidectomy reduced pain and itching while accelerating complete wound healing at 4 weeks compared to washing with warm water alone in adult patients.
Annals of Coloproctology, 2024Topical therapy with 4% chlorhexidine digluconate products resolved clinical signs in all dogs with superficial pyoderma, including those with meticillin-resistant strains, showing comparable efficacy to systemic amoxicillin-clavulanic acid.
Veterinary Dermatology, 2015Repeated application of concentrated water-in-oil emulsions over four weeks caused no skin irritation, positively affected skin properties, and delivered almost 50% of the applied fluorescein sodium, with isopropyl myristate showing superior penetration performance compared to liquid paraffin in healthy volunteers.
International Journal of Pharmaceutics, 2019Increasing the softness of pressure-sensitive adhesives using isopropyl myristate decreased pain and stripped corneocytes during removal without significantly changing human skin dermal peeling force.
Skin Research and Technology, 2007A modern cold cream formulation using a self-emulsionable excipient with isopropyl myristate shows improved preparation ease, stability, rheological qualities, and moisture and emollient power compared to traditional cerates.
Bollettino Chimico Farmaceutico, 1996
Why other moisturizers fit dry skin better
A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin.
Acta Dermato-venereologica, 2017Glycerol accelerates barrier repair and improves stratum corneum hydration compared to untreated and base-treated sites.
Acta Dermato-venereologica, 1999
Ingredients
Benzalkonium Chloride, Chlorhexidine Dihydrochloride, Liquid Paraffin, Isopropyl Myristate, Cetostearyl Alcohol, Cetomacrogol 1000, Phenoxyethanol, Water
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Specialist dermatologist, MBBS, MD, IFAAD
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Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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