# Dermisa Skin Fade Cream for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Dermisa](https://lovi.care/skincare/ie/brands/dermisa)
Category: [Serums and treatments](https://lovi.care/skincare/ie/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate skin brightening for your normal skin due to niacinamide and Phyllanthus Emblica Fruit Extract, which help to even skin tone and provide antioxidant activity.
- While Glycyrrhiza Glabra Root Extract offers mild soothing effects, the formulation lacks sufficient humectants to optimally address your redness and irritation.
- The product is generally safe for your sensitive skin, though the presence of Ethanol and Ascorbic Acid carries a slight risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Ascorbic Acid, Hydroquinone, Niacinamide, Licorice Root Extract, Phyllanthus Emblica Fruit Extract

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical application of a 0.1% amla branch extract gel demonstrated superior anti-skin aging efficacy, including skin lightening, enhanced elasticity and hydration, and wrinkle reduction in 20 volunteers compared to a placebo over 84 days. ([Journal of Traditional and Complementary Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34522633/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- TFC-1067 and 2% hydroquinone both significantly lightened facial dyschromia after 8 and 12 weeks in 48 healthy female subjects, but only hydroquinone also lightened normal skin. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33098161/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical application of Emblica officinalis accelerates dermal wound contraction and closure, and increases cellular proliferation, collagen cross-linking, and antioxidant activity in rats. ([Wound Repair and Regeneration, 2009](https://pubmed.ncbi.nlm.nih.gov/19152656/))
- PVP/CS/Phyllanthus emblica nanofiber dry facial masks containing 29.0% Phyllanthus emblica achieve a tyrosinase inhibition rate of 99.53%, complete agent release in twenty minutes, cell activity of at least 82.60%, and confine inflammatory factors. ([Polymers, 2022](https://pubmed.ncbi.nlm.nih.gov/36365465/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model. ([Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/))

## What reviewers say

Users report mixed results with this skin fade cream, with many appreciating its lightweight, non-greasy texture and suitability for various skin types. However, a significant number of users note that results for hyperpigmentation, acne scars, and sunspots are often subtle or require long-term, consistent use to become visible.

- Liked: Lightweight, non-greasy texture (often mentioned)
- Disliked: Slow or minimal results (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Liked: Good under makeup (sometimes noted)
- Liked: Improves skin tone (sometimes noted)
- Disliked: Not for severe spots (sometimes noted)
- Disliked: Potential for breakouts (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Dermisa Skin Fade Cream work for sensitive skin?

This cream works for sensitive skin, though other products fit it better because it lacks enough hydrating ingredients to properly calm redness and irritation, and the alcohol and vitamin C in it carry a slight risk of stinging. A treatment of this type needs soothing extracts and plenty of hydrating components to keep sensitive skin calm and comfortable.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Journal of Traditional and Complementary Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34522633/)

### Which ingredients make this cream a good fit for sensitive skin?

Niacinamide, Phyllanthus Emblica Fruit Extract, and Licorice Root Extract make this cream a reasonable fit for sensitive skin by helping to even skin tone, provide antioxidants, and offer mild soothing effects. However, a treatment for this skin needs extra hydrating ingredients to properly calm redness and irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Journal of Traditional and Complementary Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34522633/)

### What does Vitamin C do for sensitive skin?

Vitamin C helps brighten skin, smooth out fine lines, and fade dark spots. Clinical studies show it is generally safe and well-tolerated when improving overall skin quality.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### What does Hydroquinone do for sensitive skin?

Hydroquinone is unlikely to be a good fit for sensitive skin because it may easily trigger skin irritation, redness, and inflammatory reactions. Sensitive skin of this type needs gentle brightening ingredients like polyhydroxy acids or Rumex occidentalis to help lighten dark spots safely.
Sources: [Experimental Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36463492/), [Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15002656/)

### Where does this cream go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. It is generally safe for sensitive skin, though it may carry a slight risk of irritation from ingredients like alcohol and vitamin C. To better fit sensitive skin, a product of this type needs soothing plant extracts and plenty of gentle moisture-locking ingredients to calm redness and irritation.

### Can I use this cream with retinol, and in what order?

You can use this treatment in your evening routine, but apply it after your soothing toner and before your moisturizer, keeping it away from when you use retinol to lower the chance of redness. Because this cream lacks enough ingredients that draw in moisture, sensitive skin also needs gentle, hydrating ingredients to properly calm and soothe dryness.

### How often should I use this cream?

You can use this treatment in your evening routine once a week to start, as it is generally safe for sensitive skin though ethanol and ascorbic acid carry a slight risk of irritation. To better fit sensitive skin and address redness, this type of product needs extra calming ingredients and enough hydrating components.

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts for your sensitive skin, as reviewers only occasionally mention breakouts. To safely care for sensitive skin, a treatment like this needs soothing ingredients and lightweight hydrators that calm redness without heavy oils.

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (ethanol).

## Alternatives for sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ie/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €185.00 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €29.07 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ie/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — €22.51 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ie/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — €56.86 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/ie/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €21.81 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/ie/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €39.35 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Water, Glyceryl Stearate, Peg-100 Stearate, Niacinamide, Caprylic Capric Triglyceride, Propylene Glycol, Stearic Acid, Cetyl Alcohol, Stearyl Stearate, Ethylhexyl Methoxycinnamate, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin, Glycereth-2 Cocoate, Phyllanthus Emblica Fruit Extract, Ethanol, Dimethicone, Xanthan Gum, Sorbic Acid, Ascorbic Acid, Tocopheryl Acetate, Aminomethyl Propanol, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Hydroquinone, Octyl Dimethyl Paba
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/dermisa/skin-fade-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/sensitive-skin (this page)
- Germany: https://lovi.care/skincare/de/p/dermisa/skin-fade-cream/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/dermisa/skin-fade-cream/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/dermisa/skin-fade-cream/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/dermisa/skin-fade-cream/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/dermisa/skin-fade-cream/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/dermisa/skin-fade-cream/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/dermisa/skin-fade-cream/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/dermisa/skin-fade-cream/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/dermisa/skin-fade-cream/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/dermisa/skin-fade-cream/for/sensitive-skin