# Derma E Retinol Concentrated Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Derma E](https://lovi.care/skincare/ie/brands/derma-e)
Category: [Serums and treatments](https://lovi.care/skincare/ie/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, this serum utilizes retinol and bakuchiol to effectively minimize fine lines and wrinkles by promoting exfoliation and regulating sebum production.
- It offers moderate benefits for your acne, blemishes, and breakouts, with ingredients like sodium hyaluronate and allantoin providing hydration and soothing effects.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Encapsulated Retinol, Bakuchiol, Punica Granatum Extract, Astaxanthin, Sodium Hyaluronate

## What the research says

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Astaxanthin-loaded polyhydroxybutyrate microbeads achieved 98.1% encapsulation efficiency with sustained release, reduced degradation by 2-fold compared to unencapsulated astaxanthin, and showed no cytotoxicity or skin irritation in human cells and tests. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38072340/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Topical application of a serum containing supramolecular Bakuchiol and Terminalia chebula extract significantly improved barrier function, reduced redness and sensitivity, and improved wrinkles and elasticity in 34 Chinese subjects with sensitive skin after 28 days. ([Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/))
- Bakuchiol functions as an anti-aging compound through retinol-like regulation of gene expression, producing significant improvements in lines, wrinkles, pigmentation, elasticity, firmness, and photo-damage after 12 weeks of twice-a-day facial application without usual retinol therapy-associated undesirable effects. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24471735/))
- Phenolic-rich pomegranate peel extract formulated into a serum and mask showed significantly better facial skin lightening efficacy than placebo in 30 volunteers over 28 days. ([Planta Medica, 2020](https://pubmed.ncbi.nlm.nih.gov/32428937/))
- Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26203268/))
- A topical microemulsion containing Punica granatum extract significantly reduced skin erythema and melanin compared to a placebo in healthy Asian subjects over 12 weeks. ([Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25610348/))
- Oral astaxanthin supplementation significantly restored moisture content and improved elasticity but did not significantly decrease wrinkle depth compared to placebo in humans. ([Nutrients, 2021](https://pubmed.ncbi.nlm.nih.gov/34578794/))
- Combining oral and topical astaxanthin in 30 healthy females improved skin wrinkles, age spots, elasticity, texture, and moisture, while 6 mg daily oral supplementation in 36 healthy males improved crow's feet wrinkles, elasticity, and transepidermal water loss. ([Acta Biochimica Polonica, 2012](https://pubmed.ncbi.nlm.nih.gov/22428137/))
- Twice-daily application of a novel topical antioxidant formulation safe, well-tolerated, and effective in improving overall skin quality, fine lines, wrinkles, radiance, and hyperpigmentation in 32 healthy female subjects over 12 weeks. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37608511/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, this serum is frequently praised for being gentle and suitable for sensitive skin, effectively improving texture and firmness. Many users report positive results without irritation, making it a good option for those new to retinol. Some users express frustration with the dropper design, and a few mention slow results or a sticky texture.

- Liked: Gentle on skin (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Absorbs quickly (sometimes noted)
- Liked: Good for beginners (sometimes noted)
- Disliked: Dropper design issues (sometimes noted)
- Disliked: Slow results (rarely noted)
- Disliked: Sticky texture (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes DERMA E Retinol Serum a great fit for oily acne-prone skin?

DERMA E Retinol Concentrated Serum is a great fit for your oily acne-prone skin because it uses retinol and bakuchiol to clear pores and balance oil while smoothing fine lines. It also includes sodium hyaluronate and allantoin to provide light hydration and keep your skin calm. The formula has a very safe profile and is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

This serum is a great fit because retinol and bakuchiol help smooth fine lines by encouraging skin renewal and balancing oil, while sodium hyaluronate and allantoin add light hydration and keep things calm. It is unlikely to cause irritation on oily skin.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Encapsulated Retinol do for oily acne-prone skin?

Encapsulated retinol helps reduce blemishes and excess oil on oily, acne-prone skin while causing much less irritation than standard formulas. This ingredient works deep within the skin to smooth out texture and keep pores clear, though any product of this type also needs soothing ingredients to keep skin calm and balanced.
Sources: [Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/), [Life, 2024](https://pubmed.ncbi.nlm.nih.gov/39459512/)

### What does Bakuchiol do for oily acne-prone skin?

Bakuchiol helps clear oily acne-prone skin by reducing pimples and dark spots left behind. It is gentle on the face and is unlikely to cause the heavy peeling or stinging that often comes with traditional acne treatments.
Sources: [Journal of Drugs in Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33683079/), [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in your evening routine, applied after cleansing and toning and before your moisturizer. Putting it in the evening keeps things simple and safer around sun exposure.

### Can I use this serum with vitamin C, and in what order?

You can use this serum with vitamin C by applying vitamin C in your morning routine and this treatment serum at night. It is unlikely to irritate your oily skin because it lacks harsh ingredients, though introducing them slowly helps your skin adjust safely.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### How often should I use this serum?

This serum fits your oily acne-prone skin well and is best used in the evening as part of your routine. You may start using it once a week, and if your skin feels comfortable and you see good results, you can carefully use it more often.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is a great fit for your oily acne-prone skin because it uses retinol and bakuchiol to regulate oil and promote gentle exfoliation. It is unlikely to cause irritation or breakouts, and hydrating ingredients like sodium hyaluronate help keep your skin calm and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/ie/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — €14.94 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €29.07 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €31.40 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — €95.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ie/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ie/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — €16.50 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Retinol, Bakuchiol, Astaxanthin, Sodium Hyaluronate, Punica Granatum Fruit Extract, Aspalathus Linearius Extract, Allantoin, Sodium Pca, Caprylic Capric Triglyceride, Carbomer, Leuconostoc Radish Root Ferment Filtrate, Potassium Hydroxide, Potassium Sorbate, Sodium Benzoate, Polysorbate 20, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin (this page)
- Germany: https://lovi.care/skincare/de/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin
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