# Derma E Pure Biome Balancing Cleanser for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Derma E](https://lovi.care/skincare/ie/brands/derma-e)
Category: [Cleansers](https://lovi.care/skincare/ie/best/cleansers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other cleansers fit it better.

## Why this fit

- Offers moderate cleansing for your normal skin due to decyl glucoside and glycerin, which gently remove impurities while maintaining hydration.
- While ingredients like Centella Asiatica and panthenol provide general soothing and humectant benefits, they do not directly address your primary concern of wrinkles and fine lines.
- The product is safe for your normal skin, with no risks of irritation from harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Cell Culture Meristem Cell Culture, Lactobacillus Panax Ginseng Root Extract Ferment Filtrate, Camellia Sinensis Leaf Extract, Glycerin, Allantoin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects. ([Rejuvenation Research, 2015](https://pubmed.ncbi.nlm.nih.gov/25867599/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline. ([Journal of Toxicology and Environmental Health. Part A, 2020](https://pubmed.ncbi.nlm.nih.gov/32564709/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## Why other cleansers fit mature skin better

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))

## What reviewers say

This sulfate-free gel cleanser is highly praised by users with sensitive and reactive skin for its ability to clean effectively without causing dryness or irritation. While it is celebrated for calming redness and maintaining skin balance, some users remain skeptical about the actual impact of its prebiotic/postbiotic ingredients given the short contact time during washing.

- Liked: Gentle on skin (often mentioned)
- Liked: Non-stripping formula (often mentioned)
- Liked: Calms redness/irritation (sometimes noted)
- Liked: Fragrance-free (sometimes noted)
- Disliked: Potential for sensitivity (rarely noted)
- Disliked: Questionable biome claims (rarely noted)
- Disliked: Scent formula changes (rarely noted)

## How to apply

- Use your cleanser as part of both your AM and PM routine. Start using it daily since your skin is normal and not sensitive.
- Apply this first in your routine before using your toner, moisturizer, and SPF.
- Gently massage the cleanser onto your face using circular motions, then rinse well with water. Avoid rubbing your skin too hard.
- Apply the cleanser directly onto slightly damp skin for the best fresh feeling. Make sure your face is clean of heavy makeup first.
- Avoid the sensitive eye area while washing. Do a quick patch test before your very first use to be safe.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### How well does DERMA E Pure Biome Balancing Cleanser work for mature skin?

This cleanser works okay for mature skin by gently washing away dirt while keeping the skin soft, though it lacks ingredients that directly target wrinkles and fine lines. A cleanser for mature skin needs to be very safe, effectively smooth out wrinkles and fine lines with high-quality hydrating ingredients, and clean exceptionally well while keeping the skin balanced.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cleanser a good fit for mature skin?

Glycerin, Centella Asiatica cell culture, and panthenol help keep mature skin hydrated and calm. To be a better fit for mature skin, a cleanser of this type needs ingredients that directly target wrinkles and fine lines.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Centella Asiatica do for mature skin?

Centella asiatica helps mature skin by supporting firmness, smoothing the look of lines, and keeping moisture locked in. It is unlikely to irritate and may protect against daily environmental stress that ages the skin.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516082/), [Scientific Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34188145/)

### What does Lactobacillus Ferment do for mature skin?

Lactobacillus Ferment helps mature skin by strengthening the skin barrier and increasing moisture while reducing inflammation and signs of aging. This ingredient supports the skin microbiome and provides antioxidant benefits that keep the skin looking smooth and healthy.
Sources: [Annals of Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41044805/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39248208/)

### Where does it go in a skincare routine for mature skin?

This cleanser goes in your morning and evening routine as the first cleansing step, or as the second step after a makeup remover at night. It safely washes away impurities while keeping your skin calm and hydrated, though a mature routine also needs dedicated wrinkle-fighting active treatments.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser with retinol, applying it before your retinol treatment in your evening routine. It is unlikely to irritate your skin, but a cleanser for mature skin also needs ingredients like peptides or retinoids to help smooth fine lines and wrinkles.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use it?

You can use this cleanser daily in the morning and evening as part of your routine. A consistent cleansing routine helps keep skin clean while maintaining hydration and calm.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can this cleanser clog pores, cause breakouts or purging for mature skin?

This cleanser is unlikely to clog pores or cause breakouts for mature skin, as it gently removes impurities without using heavy, pore-clogging ingredients. However, because it is an average fit for mature skin, a product for this skin type typically needs ingredients that actively smooth fine lines and boost firmness, like peptides or retinoids.

### Can I use it around the eyes or on my body?

Yes, you can use this cleanser on the body and around the eyes, as its gentle ingredients are safe for these areas. However, because the skin around the eyes is very thin, a product for mature skin needs targeted anti-wrinkle ingredients to smooth fine lines.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Stearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [SOME BY MI Snail Truecica Miracle Repair Low pH Gel Cleanser](https://lovi.care/skincare/ie/p/some-by-mi/snail-truecica-miracle-repair-low-ph-gel-cleanser/for/mature-skin) — Superior fit — €18.98 at Amazon
- [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ie/p/cerave/foaming-facial-cleanser/for/mature-skin) — High fit — €21.45 at Amazon
- [Banila Co Clean It Zero Foam Cleanse Hydration](https://lovi.care/skincare/ie/p/banila-co/clean-it-zero-foam-cleanse-hydration/for/mature-skin) — High fit — €21.00 at Amazon

## Pairs well with

- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ie/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €14.28 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/ie/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €50.82 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ie/p/torriden/dive-in-mild-sunscreen/for/mature-skin) — Superior fit — €26.27 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Decyl Glucoside, Stearyl Alcohol, Panthenol, Centella Asiatica Cell Culture Meristem Cell Culture, Inulin, Ganoderma Lucidum Extract Mushroom Extract, Lactobacillus Panax Ginseng Root Extract Ferment Filtrate, Xanthophyll Lutein, Cucumis Sativus Fruit Extract, Panax Quinquefolius Root Extract Panax Ginseng Root Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Ombopogon Schoenanthus Extract, Allantoin, Aloe Barbadensis Leaf Juice, Pinus Pinaster Bark Extract, Glyceryl Stearate Citrate, Xanthan Gum, Sucrose, Tapioca Starch, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin (this page)
- Germany: https://lovi.care/skincare/de/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- France: https://lovi.care/skincare/fr/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin