d'Alba Piedmont White Truffle First Spray Serum for skin with dark spots

How to apply

Questions and answers

What the research says

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated.

  Antioxidants, 2021

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• A combination of five-colored plants (mung bean, white truffle, black truffle, chrysanthemum, and Lycium barbarum) at 0.5% concentration improved fibroblast wound healing by 59.89%, reduced cellular senescence markers by 76.32%, and increased epidermal thickness and collagen levels in an ex vivo skin model compared to a negative control.

  Clinical, Cosmetic and Investigational Dermatology, 2025

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline.

  Journal of Cosmetic and Laser Therapy, 2006

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical cream containing saffron extract and avocado oil improved wrinkle grading, reduced nasolabial fold area and volume, and increased skin elasticity in twenty healthy volunteers over 12 weeks without allergic reactions.

  Journal of Cosmetic Dermatology, 2020

• Topical treatment with SSFAO 50% or avocado oil increased wound contraction, reepithelialization, collagen density, and tensile strength while showing anti-inflammatory activity compared to petroleum jelly in rats.

  Evidence-based Complementary and Alternative Medicine, 2013

• Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.

  Journal of Cosmetic Dermatology, 2023

Ingredients

Water, Dipropylene Glycol, Neopentyl Glycol Diheptanoate, 1,2-Hexanediol, Niacinamide, Sorbitol, Hydroxyethyl Urea, Persea Gratissima Oil Avocado Oil, Salvia Hispanica Seed Extract, Ocimum Basilicum Stem Extract Flower Leaf, Betaine, Avena Sativa Kernel Extract Oat Kernel Extract, Butylene Glycol, Tuber Magnatum Extract, Glycerin, Helianthus Annuus Seed Oil Sunflower Seed Oil, Tocopheryl Acetate, Disodium Edta, Dipotassium Glycyrrhizate, Adenosine, Sodium Palmitoyl Proline, Bifida Lysate Ferment, Nymphaea Alba Flower Extract, Sodium Hyaluronate, Alcohol, Glycine Soja Oil Soybean Oil, Veronica Officinalis Extract, Primula Veris Extract, Peppermint Leaf Extract, Melissa Officinalis Leaf Extract, Malva Sylvestris Extract, Alchemilla Vulgaris Extract, Achillea Millefolium Extract, Saussurea Involucrata Extract, Panax Ginseng Root Extract, Nelumbo Nucifera Flower Extract, Morus Alba Bark Extract, Lilium Candidum Flower Extract, Leontopodium Alpinum Extract, Houttuynia Cordata Extract, Freesia Refracta Extract, Carbomer, Bellis Perennis Flower Extract, Arginine, Potassium Sorbate, Bixa Orellana Seed Extract, Sodium Hydroxide, Tocopherol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.