# Clinique Dramatically Different Moisturizing Gel for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Superior · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Clinique](https://lovi.care/skincare/ie/brands/clinique)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration for your oily skin, with glycerin and sodium hyaluronate providing excellent moisturizing benefits without exacerbating oiliness. However, it lacks specialized ingredients to target your primary concerns of acne, blemishes, and breakouts.
- The formula is well-suited for oily skin due to dimethicone and glycerin, which offer emollient and humectant actions respectively, ensuring optimal hydration.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components like Laminaria Digitata Extract and Saccharomyces Lysate Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Glycerin, Sodium Hyaluronate, Dimethicone, Laminaria Digitata Extract, Cucumis Sativus Fruit Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A novel anti-aging serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate, gluconolactone, niacinamide, and laminaria extract significantly increased anti-aging biomarkers and improved static and dynamic wrinkles as well as skin quality in clinical studies. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/41668671/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- A skincare regimen containing Macrocystis pyrifera ferment consisting of a cleansing foam, a serum, and a moisturizer decreases the visible effects of inflammation and aging while promoting healing and improving patient satisfaction. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38922798/))
- Macrocystis pyrifera ferment-containing creams decrease visible inflammation and signs of aging while enhancing barrier resilience and recovery. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38041526/))
- Aqueous extracts from Macrocystis pyrifera and Durvillaea antarctica exhibited antiviral activity against acyclovir-sensitive and acyclovir-resistant HSV-1 and HSV-2, and topical formulations significantly reduced the severity and duration of HSV-1 skin lesions in an animal model compared to mock treatment and acyclovir. ([Frontiers in Microbiology, 2020](https://pubmed.ncbi.nlm.nih.gov/33013743/))
- Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38336313/))
- Copper Oxide nanoparticles synthesized using cucumber extract exhibited antibacterial, antifungal, UV protection, and reactive-oxygen species inhibition properties with low cellular toxicity and skin-rejuvenating effects when incorporated into skin cream. ([Endocrine, Metabolic & Immune Disorders Drug Targets, 2021](https://pubmed.ncbi.nlm.nih.gov/32628604/))
- Topical treatment with Holothuria parva extract gel showed significant wound contraction compared to the negative control in full-thickness wounded rats. ([The International Journal of Lower Extremity Wounds, 2024](https://pubmed.ncbi.nlm.nih.gov/34791922/))

## Why other moisturizers fit oily acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

This oil-free gel is a highly-rated favorite for oily and combination skin, appreciated for its very lightweight, fast-absorbing texture that hydrates without feeling heavy or clogging pores. It also performs well as a base for makeup. However, a significant number of users with dry skin or in colder climates find it not moisturizing enough, and a small number report breakouts or reactions.

- Liked: Lightweight absorption (mostly mentioned)
- Liked: Controls oil (often mentioned)
- Liked: Good under makeup (often mentioned)
- Disliked: Not moisturizing enough (often mentioned)
- Liked: Non-irritating formula (sometimes noted)
- Disliked: Pricey for basics (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Clinique Dramatically Different Moisturizing Gel work for oily acne-prone skin?

Clinique Dramatically Different Moisturizing Gel works reasonably well for oily acne-prone skin by providing moderate hydration with glycerin and sodium hyaluronate without making your face greasy. However, it lacks specialized ingredients to target breakouts and blemishes. A moisturizer for this skin type needs targeted blemish-fighting ingredients alongside lightweight hydration to manage acne while keeping skin balanced.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this moisturizer a good fit for oily acne-prone skin?

Glycerin and sodium hyaluronate make this moisturizer a good fit for oily skin by providing essential hydration without adding excess oil, while dimethicone leaves skin feeling smooth. This type of skin also needs specialized ingredients that clear breakouts and target blemishes without clogging pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### Where does it go in a skincare routine for oily acne-prone skin?

This moisturizer goes in your morning and evening routine after your toner and before your sunscreen or treatment. It offers moderate hydration and has a very safe formula with no harsh ingredients, but a better product for this skin needs specialized acne-fighting and blemish-targeting ingredients.

### Can I use this moisturizer with retinol, and in what order?

You can use this moisturizer with retinol by applying the retinol first and following with the moisturizer. This helps keep your skin comfortable and minimizes dryness without clogging your pores. Oily acne-prone skin still needs acne-fighting ingredients like salicylic acid or benzoyl peroxide to truly clear breakouts.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use it?

You can use this moisturizer twice a day, in the morning and evening, to keep your oily skin hydrated without feeling greasy. Daily application of moisturizers with glycerin and sodium hyaluronate helps improve skin moisture and supports the skin barrier.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this moisturizer clog pores, cause breakouts or purging for oily acne-prone skin?

This moisturizer is unlikely to cause breakouts or clog pores on your oily skin because it has an excellent safety profile and lacks harsh ingredients. However, an oily acne-prone skin needs targeted ingredients that actively clear blemishes and prevent breakouts.

### Can I use it around the eyes or on my body?

This moisturizer is safe to use around the eyes or on the body, though the skin around your eyes is thinner and requires extra care with gentle application. Glycerin helps maintain hydration across different skin thicknesses without feeling heavy.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this moisturizer fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ie/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — €14.07 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ie/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — €18.99 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/ie/p/belif/the-true-cream-aqua-bomb/for/oily-acne-prone-skin) — High fit — €35.01 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — €95.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ie/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ie/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-acne-prone-skin) — Superior fit — €15.64 at Amazon

## Where to buy

- Notino: €17.50 (https://www.notino.ie/clinique/3-steps-dramatically-different-moisturizing-gel-for-combination-oily-to-oily-skin/p-68905/)
- Lookfantastic: €42.55 (https://www.lookfantastic.ie/p/clinique-dramatically-different-moisturising-gel-125ml/11144718/)
Prices checked 16 Oct – 17 Oct 2026.

## Ingredients

Water, Dimethicone, Isododecane, Butylene Glycol, Bis-Peg-18 Methyl Ether Dimethyl Silane, Glycerin, Laminaria Digitata Extract, Polygonum Cuspidatum Root Extract, Saccharomyces Lysate Extract, Cucumis Sativus Fruit Extract, Hordeum Vulgare Extract Extrait Dorge Extract, Helianthus Annuus Seedcake Sunflower Seedcake, Caffeine, Trehalose, Sodium Hyaluronate, Tocopheryl Acetate, Polysilicone-11, Silica, Propylene Glycol Dicaprate, Oleth-10, Lactobacillus Ferment, Laureth-23, Laureth-4, Ammonium Acryloyldimethyltaurate Vp Copolymer, Carbomer, Caprylyl Glycol, Hexylene Glycol, Tromethamine, Disodium Edta, Phenoxyethanol, Potassium Sorbate, Yellow 5 Ci 19140, Red 4 Ci 14700, Ci 15985
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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