# Clinique Dramatically Different Moisturizing Gel for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Superior · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Clinique](https://lovi.care/skincare/ie/brands/clinique)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- This product offers moderate hydration for your combination skin, with glycerin and sodium hyaluronate providing excellent moisturizing benefits without exacerbating oiliness. Laminaria Digitata Extract and Saccharomyces Lysate Extract contribute to soothing the skin, making it generally well-tolerated.
- While it addresses general hydration needs effectively, it lacks specialized ingredients to target your specific concerns of acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Sodium Hyaluronate, Dimethicone, Laminaria Digitata Extract, Cucumis Sativus Fruit Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38336313/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- A skincare regimen containing Macrocystis pyrifera ferment consisting of a cleansing foam, a serum, and a moisturizer decreases the visible effects of inflammation and aging while promoting healing and improving patient satisfaction. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38922798/))
- Macrocystis pyrifera ferment-containing creams decrease visible inflammation and signs of aging while enhancing barrier resilience and recovery. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38041526/))
- Aqueous extracts from Macrocystis pyrifera and Durvillaea antarctica exhibited antiviral activity against acyclovir-sensitive and acyclovir-resistant HSV-1 and HSV-2, and topical formulations significantly reduced the severity and duration of HSV-1 skin lesions in an animal model compared to mock treatment and acyclovir. ([Frontiers in Microbiology, 2020](https://pubmed.ncbi.nlm.nih.gov/33013743/))
- Copper Oxide nanoparticles synthesized using cucumber extract exhibited antibacterial, antifungal, UV protection, and reactive-oxygen species inhibition properties with low cellular toxicity and skin-rejuvenating effects when incorporated into skin cream. ([Endocrine, Metabolic & Immune Disorders Drug Targets, 2021](https://pubmed.ncbi.nlm.nih.gov/32628604/))
- Topical treatment with Holothuria parva extract gel showed significant wound contraction compared to the negative control in full-thickness wounded rats. ([The International Journal of Lower Extremity Wounds, 2024](https://pubmed.ncbi.nlm.nih.gov/34791922/))

## Why other moisturizers fit acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

This oil-free gel is a highly-rated favorite for oily and combination skin, appreciated for its very lightweight, fast-absorbing texture that hydrates without feeling heavy or clogging pores. It also performs well as a base for makeup. However, a significant number of users with dry skin or in colder climates find it not moisturizing enough, and a small number report breakouts or reactions.

- Liked: Lightweight absorption (mostly mentioned)
- Liked: Controls oil (often mentioned)
- Liked: Good under makeup (often mentioned)
- Disliked: Not moisturizing enough (often mentioned)
- Liked: Non-irritating formula (sometimes noted)
- Disliked: Pricey for basics (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Clinique Dramatically Different Moisturizing Gel work for acne-prone skin?

Clinique Dramatically Different Moisturizing Gel works reasonably well for acne-prone skin by providing light hydration and a calm feel without clogging pores or causing irritation. However, because it lacks specialized ingredients to target blemishes and breakouts, acne-prone skin needs a moisturizer of this type to include targeted blemish-fighting ingredients and soothing plant extracts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this moisturizer a good fit for acne-prone skin?

Glycerin and sodium hyaluronate help provide light moisture without making your skin oily. To better fit acne-prone skin, a moisturizer of this type needs specialized ingredients that actively target blemishes and breakouts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glycerin do for acne-prone skin?

Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Where does it go in a skincare routine for acne-prone skin?

This moisturizer goes as the last step in the morning and evening, right before sunscreen or makeup. While it gives good basic hydration, acne-prone skin needs a product with targeted blemish-fighting ingredients to properly manage breakouts.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use it with retinol, and in what order?

You can use this moisturizer with retinol to keep your skin calm and hydrated without adding extra oiliness. Apply it after your retinol treatment to help reduce potential dryness and irritation. To properly support acne-prone skin, a product of this type needs specialized blemish-fighting ingredients and skin-clearing actives.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use it?

You can use this moisturizer twice a day, morning and night, to keep your skin hydrated without feeling oily. Daily application helps maintain skin comfort and supports the moisture barrier.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can it clog pores, cause breakouts or purging for acne-prone skin?

This moisturizer is unlikely to cause irritation or breakouts because it has a very safe formula with soothing ingredients. However, it lacks specialized ingredients to clear blemishes, so acne-prone skin needs products with targeted active ingredients to effectively manage breakouts.

### Can I use it around the eyes or on my body?

You can use this moisturizer around your eyes and on your body because its gentle formula hydrates well without feeling heavy or causing irritation. To properly care for acne-prone skin in those areas, a product of this type needs specialized blemish-fighting ingredients and targeted acne treatments.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ie/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.99 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ie/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — €14.07 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/ie/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — €35.01 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/ie/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.40 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ie/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.99 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/ie/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — €17.43 at Amazon

## Where to buy

- Notino: €17.50 (https://www.notino.ie/clinique/3-steps-dramatically-different-moisturizing-gel-for-combination-oily-to-oily-skin/p-68905/)
- Lookfantastic: €42.55 (https://www.lookfantastic.ie/p/clinique-dramatically-different-moisturising-gel-125ml/11144718/)
Prices checked 16 Oct – 17 Oct 2026.

## Ingredients

Water, Dimethicone, Isododecane, Butylene Glycol, Bis-Peg-18 Methyl Ether Dimethyl Silane, Glycerin, Laminaria Digitata Extract, Polygonum Cuspidatum Root Extract, Saccharomyces Lysate Extract, Cucumis Sativus Fruit Extract, Hordeum Vulgare Extract Extrait Dorge Extract, Helianthus Annuus Seedcake Sunflower Seedcake, Caffeine, Trehalose, Sodium Hyaluronate, Tocopheryl Acetate, Polysilicone-11, Silica, Propylene Glycol Dicaprate, Oleth-10, Lactobacillus Ferment, Laureth-23, Laureth-4, Ammonium Acryloyldimethyltaurate Vp Copolymer, Carbomer, Caprylyl Glycol, Hexylene Glycol, Tromethamine, Disodium Edta, Phenoxyethanol, Potassium Sorbate, Yellow 5 Ci 19140, Red 4 Ci 14700, Ci 15985
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- United Kingdom: https://lovi.care/skincare/uk/p/clinique/dramatically-different-moisturizing-gel/for/acne-prone-skin
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