# CELL BY CELL Soft Enzyme Powder for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: CELL BY CELL
Category: [Exfoliants](https://lovi.care/skincare/ie/best/exfoliators)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other products fit it better.

## Why this fit

- Offers moderate cleansing for your oily skin, with ingredients like Sodium Cocoyl Isethionate and Sodium Lauroyl Glutamate helping to remove impurities, though it lacks stronger seboregulating components for optimal oil control.
- While Aloe Barbadensis Leaf Juice and Allantoin provide soothing benefits, the formula's primary cleansing agents are supportive rather than specifically targeted for your acne and blemishes.
- The product has a good safety profile, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the inclusion of soothing agents.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Sodium Cocoyl Isethionate, Aloe Barbadensis Leaf Juice, Collagen, Allantoin, Opuntia Ficus-Indica Stem Extract

## What the research says

- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Opuntia ficus-indica extract and its isorhamnetin-glucosyl-rhamnoside suppressed nitric oxide, COX-2, TNF-alpha, and IL-6 production in vitro and inhibited croton oil-induced ear edema in vivo. ([BioMed Research International, 2015](https://pubmed.ncbi.nlm.nih.gov/25821823/))
- Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness. ([Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Formulations containing 0.10%, 0.25%, and 0.50% freeze-dried Aloe vera extract increased stratum corneum water content compared with the vehicle in 20 female subjects, while transepidermal water loss was not modified. ([Skin Research and Technology, 2006](https://pubmed.ncbi.nlm.nih.gov/17026654/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Opuntia ficus-indica extract activated AHR-NRF2 signaling, inhibited reactive oxygen species generation, and upregulated filaggrin and loricrin expression in human keratinocytes. ([Journal of Medicinal Food, 2015](https://pubmed.ncbi.nlm.nih.gov/26061570/))
- Pre-treating normal human keratinocytes with an Opuntia ficus-indica cladode water extract protected against UVA-induced oxidative stress and apoptosis by inhibiting free radicals, lipid peroxidation, and GSH depletion. ([Bioorganic & Medicinal Chemistry Letters, 2017](https://pubmed.ncbi.nlm.nih.gov/29107540/))
- Mucilaginous and methanol extracts of Opuntia ficus-indica flowers accelerated wound contraction and improved cutaneous repair compared to the control group in rats. ([International Journal of Biological Macromolecules, 2015](https://pubmed.ncbi.nlm.nih.gov/26306411/))

## Why other products fit oily acne-prone skin better

- Two percent supramolecular salicylic acid showed similar efficacy to 0.01% adapalene plus 5% benzoyl peroxide in reducing acne lesions in 31 patients over 28 days. ([Cutaneous and Ocular Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/30173582/))
- Chemical peels with 30% supramolecular salicylic acid effectively treated acne and reduced facial sebum secretion while improving skin hydration and barrier function in 25 patients. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35073439/))
- A moisturizing cream containing 2% l-carnitine and 5% EGCG significantly reduced sebum levels and improved skin hydration in ninety subjects with seborrhea over 4 weeks, showing greater anti-sebum efficacy in the combination group compared to the l-carnitine group alone. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37194909/))

## What reviewers say

Based on limited data, users consistently describe this cleanser as an exceptionally gentle powder-to-foam exfoliant that effectively smooths skin texture without stripping moisture. It is frequently recommended for sensitive, acne-prone, and oily skin types, with many users reporting a reduction in small bumps and a baby-soft finish after use.

- Liked: Gentle exfoliation (mostly mentioned)
- Liked: Skin texture improvement (often mentioned)
- Liked: Deep cleansing (sometimes noted)
- Liked: Non-stripping (sometimes noted)
- Disliked: Packaging design (sometimes noted)
- Disliked: Clumping issues (rarely noted)
- Disliked: Messy application (rarely noted)
- Disliked: Price vs. quantity (rarely noted)

## How to apply

- Use your enzyme powder cleanser PM once a week to start, then increase frequency if your skin tolerates it well. Always apply SPF during the day since exfoliating products can make skin sensitive to the sun.
- Apply this enzyme powder cleanser in your weekly routine after the standard cleanser and before your hydrating toner and moisturizer. This step helps clear away dead skin cells.
- Mix the powder with a little water in your hands to create a gentle foam , then massage it softly onto your face while avoiding harsh rubbing.
- Apply the enzyme powder cleanser on slightly damp skin to help activate the formula effectively. Make sure your face is clean from makeup before starting.
- Avoid the delicate eye area and do a patch test before your first use. Do not mix this with strong acids or retinoids in the same routine to prevent irritation.
- Video: https://storage.pora.ai/2d8db6e67371d665a6a7736b5ed5d762.mp4

## Questions and answers

### How well does CELL BY CELL Soft Enzyme Powder work for oily acne-prone skin?

CELL BY CELL Soft Enzyme Powder works moderately well for oily acne-prone skin, removing impurities safely without causing irritation. However, it lacks strong oil-controlling and blemish-targeting components. An enzyme powder cleanser for this skin needs strong seboregulating components and targeted ingredients like Niacinamide, Papain, or Salicylic Acid for optimal oil control and blemish management.
Sources: [BioMed Research International, 2015](https://pubmed.ncbi.nlm.nih.gov/25821823/)

### Which ingredients make this cleanser a good fit for oily acne-prone skin?

Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Aloe Barbadensis Leaf Juice, and Allantoin help make this cleanser a decent fit by gently removing impurities and calming the skin. However, this skin type needs products with stronger oil-controlling components and ingredients like Niacinamide, Papain, Salicylic Acid, or Ascorbic Acid to effectively target blemishes and clear pores.
Sources: [Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/)

### What does Sodium Cocoyl Isethionate do for oily acne-prone skin?

Sodium cocoyl isethionate helps cleanse oily acne-prone skin gently without stripping the skin barrier because its large molecular structure prevents it from penetrating deep into the skin. This mild surfactant washes away dirt and excess oil while keeping the skin calm and comfortable.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/), [Dermatologic Therapy, 2004](https://pubmed.ncbi.nlm.nih.gov/14728695/)

### What does Aloe Vera Leaf Juice do for oily acne-prone skin?

Aloe Vera Leaf Juice helps calm redness and reduces acne breakouts for oily skin. Studies show it effectively targets acne lesions and lowers redness when used regularly.
Sources: [Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/), [The Journal of Dermatological Treatment, 2014](https://pubmed.ncbi.nlm.nih.gov/23336746/)

### Where does it go in a skincare routine for oily acne-prone skin?

This enzyme powder is used once a week as an exfoliating step in your routine, placed right after cleansing. It helps wash away impurities with ingredients like Sodium Cocoyl Isethionate, though oily acne-prone skin typically needs stronger oil-controlling components and blemish-fighting ingredients for optimal care.

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser in your routine when you use retinol, using the cleanser first to wash your skin and applying your retinol afterwards. The product is unlikely to cause irritation for your oily skin due to the absence of harsh ingredients and the inclusion of soothing agents.

### How often should I use it?

Start by using this enzyme powder once a week as part of your routine. Oily acne-prone skin needs a product of this type that also offers strong oil control and ingredients targeted specifically for acne and blemishes.

### Can this cleanser clog pores, cause breakouts or purging for oily acne-prone skin?

This cleanser is unlikely to clog pores or cause breakouts for your oily acne-prone skin, and it won't cause purging since it doesn't speed up cell turnover. The formula has a safe and gentle profile with soothing ingredients that help calm the skin. However, because it lacks stronger oil-controlling components and blemish-fighting ingredients, oily acne-prone skin needs products with powerful oil-regulating and targeted acne-fighting ingredients.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [VT Cica Mild Powder Wash](https://lovi.care/skincare/ie/p/vt/cica-mild-powder-wash/for/oily-acne-prone-skin) — High fit — €8.99 at Amazon
- [By Wishtrend Green Tea & Enzyme Powder Wash](https://lovi.care/skincare/ie/p/by-wishtrend/green-tea-and-enzyme-powder-wash/for/oily-acne-prone-skin) — High fit — €15.91 at Amazon
- [Dr. Barbara Sturm Enzyme Cleanser](https://lovi.care/skincare/ie/p/dr-barbara-sturm/enzyme-cleanser/for/oily-acne-prone-skin) — High fit — €66.90 at Notino

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — €95.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ie/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ie/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — €16.50 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Zea Mays Starch, Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Aloe Barbadensis Leaf Juice, Opuntia Ficus-Indica Stem Extract, Allantoin, Collagen, Sorbitol, Ascorbyl Palmitate, Isopropyl Palmitate, Grapefruit Seed Extract, Pollen Extract, Titanium Dioxide, Citric Acid, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin (this page)
- Germany: https://lovi.care/skincare/de/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin