celimax The Real Noni Energy Ampoule for mature skin

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Questions and answers

What the research says

• A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.

  Skin Pharmacology and Physiology, 2022

• Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion.

  International Journal of Dermatology, 2008

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical application of an emulsion containing a complete mixture of ceramides III, IIIB, VI, phytosphingosine, cholesterol, and linoleic acid significantly accelerated barrier recovery after SLS damage and improved skin hydration after acetone treatment in human volunteers compared to an emulsion containing only two types of ceramides.

  Journal of the European Academy of Dermatology and Venereology, 2002

• Morinda citrifolia leaf extracts increased the UVB dose required to induce erythema by almost 3.5 times compared to untreated skin and inhibited histamine H-1 receptor binding by 57% in volunteers and in vitro assays.

  Journal of Natural Medicines, 2009

• Morinda citrifolia extracts containing α-EG and pinoresinol induced stimulatory and inhibitory gene expression related to collagen and fibroblast growth factors in normal human dermal fibroblasts, with rawfs showing a lack of cell and DNA toxicity in PBMCs.

  Plants, 2022

• Topical formulations containing Morinda citrifolia extract protected the dorsal skin against UV-induced damage, including alterations in thickness, TEWL, erythema, and histology, in mice exposed to UVA-UVB light compared to unprotected skin.

  BioMed Research International, 2014

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

Ingredients

Morinda Citrifolia Fruit Extract, Butylene Glycol, Propanediol, Glycerin, 1,2-Hexanediol, Diethoxyethyl Succinate, Glyceryl Acrylate Acrylic Acid Copolymer, Morinda Citrifolia Seed Oil, Ceramide Np, Olea Europaea Oil Fruit Olive Oil Fruit, Butyrospermum Parkii Butter Shea Butter, Squalane, Rosmarinus Officinalis Oil Leaf Rosemary Oil Leaf, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Theobroma Cacao Extract, Dextrin, Phytosphingosine, Cholesterol, Sodium Hyaluronate, Hydrogenated Lecithin, C12-13 Pareth-9, Sodium Polyacryloyldimethyl Taurate, Caprylic Capric Triglyceride, Water, Allantoin, Adenosine, Disodium Edta, Chlorphenesin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.