Bobbi Brown Vitamin Enriched Face Base for sensitive skin

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Questions and answers

What the research says

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors.

  Journal of Clinical Medicine, 2023

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical riboflavin photodynamic therapy showed comparable efficacy in reducing acne lesions and fewer adverse events compared with 5-aminolevulinic acid photodynamic therapy in patients with mild to moderate facial acne.

  Photodiagnosis and Photodynamic Therapy, 2025

• Topical application of niacin derivatives increased hair fullness in sixty female subjects with female pattern hair loss compared to placebo.

  Journal of Cosmetic Dermatology, 2005

• Topical myristyl nicotinate increased skin cell NAD, stratum corneum thickness, epidermal thickness, epidermal renewal, minimal erythemal dose, and barrier resistance while reducing transepidermal water loss in subjects with photodamaged skin compared to placebo.

  Experimental Dermatology, 2007

• Topical beta-carotene provided protection for the human skin of healthy volunteers against IR radiation by acting as a superficial antioxidant, though dermal carotenoid degradation was significantly higher for standard infrared radiator than for water filter infrared irradiation.

  Experimental Dermatology, 2011

• Pre-treatment with beta-carotene at 1.5 microM modulated UVA-induced gene regulation in HaCaT human keratinocytes through multiple mechanisms not restricted to singlet oxygen quenching, reducing the effect for 143 genes and enhancing it for 180 out of 568 UVA-regulated genes.

  The Journal of Investigative Dermatology, 2005

• Alginate hydrogel dressings co-loaded with cinnamon-mediated silver nanoparticles, beta-carotene nanocarriers, and Centella asiatica extract demonstrated antimicrobial and antibiofilm activities against Staphylococcus aureus and Escherichia coli over a 24-h period while mitigating silver-induced cytotoxicity and oxidative stress in human keratinocyte cells.

  Gels, 2025

Why other moisturizers fit sensitive skin better

• Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine.

  Skin Research and Technology, 2003

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

Ingredients

Water, Cyclopentasiloxane, Bis-Diglyceryl Polyacyladipate-2, Butylene Glycol, Ppg-2 Myristyl Ether Propionate, Cetyl Alcohol, Peg-40 Stearate, Butyrospermum Parkii Butter Shea Butter, Squalane, Glyceryl Stearate, Sorbitan Stearate, Epilobium Angustifolium Extract, Yeast Extract, Beta-Carotene, Sodium Hyaluronate, Grapefruit Peel Oil, Tocopheryl Acetate, Methyl Glucose Sesquistearate, Pelargonium Graveolens Oil Flower Geranium Oil Flower, Dimethicone Crosspolymer, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Peg-20 Methyl Glucose Sesquistearate, C12-15 Alkyl Ethylhexanoate, Tetrasodium Edta, Sodium Hydroxide, Panthenol, Magnesium Ascorbyl Phosphate, Limonene, Citronellol, Geraniol, Linalool, Chlorphenesin, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.