Biossance Squalane + Marine Algae Eye Cream for mature skin

Questions and answers

What the research says

• A Dunaliella salina extract significantly reduced skin glycation scores, histamine sensitivity, wrinkle counts, and spots compared to placebo under intense solar exposure.

  Marine Drugs, 2022

• Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.

  Colloids and Surfaces. B, Biointerfaces, 2025

• Oral and topical administration of C40 carotenoids effectively alleviates skin photoaging by scavenging reactive oxygen species, enhancing collagen and elastin production, and modulating oxidative stress-responsive signaling pathways.

  Antioxidants, 2025

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate.

  Scientific Reports, 2020

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

• Treatment with lipid algae extract reduced the level of oxidized proteins in human keratinocytes and stratum corneum skin cells.

  Annals of the New York Academy of Sciences, 2004

• Topical astaxanthin-loaded algae extract hydrogel and lipogel formulations exhibited the highest antioxidant activity and successful in vitro release, suggesting their potential as anti-aging formulations.

  Journal of Cosmetic Dermatology, 2019

• Antarctic marine algae extracts increased cell viability, protected against inflammation, and enhanced the barrier integrity of human intestinal and keratinocyte cell lines damaged by lipopolysaccharide or ultraviolet radiation.

  Marine Drugs, 2022

• Oral astaxanthin supplementation significantly restored moisture content and improved elasticity but did not significantly decrease wrinkle depth compared to placebo in humans.

  Nutrients, 2021

• Combining oral and topical astaxanthin in 30 healthy females improved skin wrinkles, age spots, elasticity, texture, and moisture, while 6 mg daily oral supplementation in 36 healthy males improved crow's feet wrinkles, elasticity, and transepidermal water loss.

  Acta Biochimica Polonica, 2012

• Twice-daily application of a novel topical antioxidant formulation safe, well-tolerated, and effective in improving overall skin quality, fine lines, wrinkles, radiance, and hyperpigmentation in 32 healthy female subjects over 12 weeks.

  Journal of Cosmetic Dermatology, 2023

• Phytoene- and phytofluene-rich tomato and Dunaliella salina extracts show no significant cytotoxic, genotoxic, irritant, or sensitizing potential, supporting their safe human topical use.

  Journal of Toxicology, 2018

Ingredients

Water, Caprylic Capric Triglyceride, Squalane, Glycerin, Sorbitan Olivate, Cetearyl Olivate, Jojoba Esters, Glyceryl Stearate Se, Panthenol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Cetyl Palmitate, Spilanthes Acmella Flower Extract, Palmitoyl Tripeptide-5, Sorbitan Palmitate, Dunaliella Salina Extract, Astaxanthin, Sodium Hyaluronate, Phenoxyethanol, Ethylhexylglycerin, Tocopherol, Citric Acid

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.