# BIOEFFECT EGF Power Serum for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [BIOEFFECT](https://lovi.care/skincare/ie/brands/bioeffect)
Category: [Serums and treatments](https://lovi.care/skincare/ie/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers excellent skin regeneration for your oily skin due to the presence of Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1 and Kgf Barley Sh-Polypeptide-3, which are beneficial for treating skin concerns.
- Glycerin and Sodium Hyaluronate provide hydration suitable for oily skin, though they offer limited direct benefits for your specific concerns of acne, blemishes, and breakouts.
- The product is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Rh-Oligopeptide-1, Sodium Hyaluronate, Acetyl Glucosamine, Hordeum Vulgare Seed Extract, Glycerin

## What the research says

- Fibrin-bound keratinocyte growth factor released via cell-mediated degradation significantly enhanced wound closure in a hybrid model of full-thickness wound healing in athymic mice compared to topical KGF. ([The American Journal of Pathology, 2005](https://pubmed.ncbi.nlm.nih.gov/16314471/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone. ([The New England Journal of Medicine, 1989](https://pubmed.ncbi.nlm.nih.gov/2659995/))
- Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba. ([Lasers in Surgery and Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/30614013/))
- Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars. ([The Journal of Clinical and Aesthetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35942017/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## Why other serums fit oily acne-prone skin better

- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

This serum is highly effective for mature, dry, and aging skin, with users frequently reporting improvements in texture, firmness, and radiance. Based on limited data, the product is praised for visibly reducing fine lines and hyperpigmentation, leaving the complexion plumper and more even-toned. Some users note a tacky feel after application and that results require patience, while the high price point is a common concern.

- Liked: Improves skin texture (mostly mentioned)
- Disliked: High price point (mostly mentioned)
- Liked: Boosts skin radiance (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Liked: Deeply hydrating (sometimes noted)
- Liked: Gentle formula (sometimes noted)
- Disliked: Requires patience (sometimes noted)
- Disliked: Tacky skin feel (sometimes noted)
- Disliked: Limited care feeling (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does BIOEFFECT EGF Power Serum work for oily acne-prone skin?

This serum works moderately well for oily acne-prone skin, providing safe hydration and skin renewal without causing irritation, though it does little for breakouts. Treatments that fit this skin better need ingredients like niacinamide, propolis, or vitamin C to control excess oil and target acne while keeping the skin comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Rh-Oligopeptide-1, glycerin, and sodium hyaluronate make this serum a fit by offering skin regeneration and hydration, though it lacks specific ingredients for acne like niacinamide or vitamin C. A product for this skin needs ingredients that target excess oil and blemishes while remaining lightweight and non-irritating.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does EGF do for oily acne-prone skin?

EGF helps calm redness and breakouts, and it may improve the look of acne scars on oily skin. It also supports the skin barrier while increasing skin water and oil balance.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37841061/), [International Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24962549/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in your evening routine after cleansing and before moisturizing. It is safe for oily skin and helps renew the skin, though an oily acne-prone routine needs ingredients that directly target breakouts and blemishes.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying the treatment after your cleanser and before your moisturizer in your evening routine. This product is unlikely to cause irritation on your oily skin, though an oily acne-prone skin type needs targeted ingredients like salicylic acid or benzoyl peroxide to directly manage breakouts.

### How often should I use this serum?

This treatment serum works well in your evening routine, where you can safely apply it on clean skin once a day or a few times a week. It is safe for oily skin and unlikely to cause irritation, though managing breakouts effectively typically requires targeted ingredients like salicylic acid or benzoyl peroxide.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to clog pores or cause irritation for your oily skin, as it contains gentle ingredients without harsh components. However, because it offers limited direct care for acne and breakouts, an oily acne-prone skin type needs added ingredients like salicylic acid or niacinamide to truly clear and balance blemishes.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/ie/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — €14.94 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €29.07 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €31.40 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — €95.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ie/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ie/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — €16.50 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Glycerin, Water, Sodium Citrate, Acetyl Glucosamine Nag, Isopentyldiol, Phenoxyethanol, Sodium Chloride, Sodium Hyaluronate, Citric Acid, Hordeum Vulgare Seed Extract, Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1, Kgf Barley Sh-Polypeptide-3
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin (this page)
- Germany: https://lovi.care/skincare/de/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin