Vitamin C and tromethamine

Questions and answers

Research on vitamin C and tromethamine

• Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo

  Vitamin C · Experimental Dermatology, 2003

• Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial

  Vitamin C · Journal of Cosmetic Dermatology, 2020

• Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives

  Vitamin C · Journal of Cosmetic Dermatology, 2012

• Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo

  Vitamin C · Journal of Periodontology, 2009

• Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study

  Vitamin C · Clinical Oral Investigations, 2021

• Skin moisturizing effect and skin penetration of ascorbyl palmitate entrapped in solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) incorporated into hydrogel

  Vitamin C · Die Pharmazie, 2005

• Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging-A split-face comparative study

  Vitamin C · Dermatologic Therapy, 2022

• Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin

  Vitamin C · Antioxidants, 2024

• Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days

  Vitamin C · Journal of Cosmetic Dermatology, 2019

• Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment

  Vitamin C · International Journal of Cosmetic Science, 2009

• Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques

  Vitamin C · European Journal of Pharmaceutics and Biopharmaceutics, 2017

• Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin

  Vitamin C · Photochemistry and Photobiology, 2012

• Derivatives of L-Ascorbic Acid in Emulgel: Development and Comprehensive Evaluation of the Topical Delivery System

  Vitamin C · Pharmaceutics, 2023

• Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers

  Vitamin C · Drug Research, 2017

• Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders

  Vitamin C · Polymers, 2023

• Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid

  Vitamin C · Pharmaceutics, 2024

• Efficacy of ethyl ascorbyl ether-containing cosmetic cream on blue light-induced skin changes

  Vitamin C · Journal of Cosmetic Dermatology, 2022

• Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers

  Vitamin C · Journal of Cosmetic Dermatology, 2021

• Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials

  Vitamin C · Frontiers in Pharmacology, 2025

• Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes

  Vitamin C · Free Radical Biology & Medicine, 2025

• Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects

  Vitamin C · Experimental Dermatology, 2012

• Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations

  Vitamin C · International Journal of Cosmetic Science, 2004

• Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients

  Vitamin C · International Journal of Biological Macromolecules, 2026

• Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability

  Vitamin C · Journal of Liposome Research, 2025

• Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos

  Vitamin C · International Journal of Molecular Sciences, 2024

• Open-label topical application of tetrahexyldecyl ascorbate and acetyl zingerone containing serum improves the appearance of photoaging and uneven pigmentation

  Vitamin C · Journal of Cosmetic Dermatology, 2024

• Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial

  Vitamin C · Cureus, 2026

Behind this pairing advice

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