# Ergothioneine Page: https://lovi.care/skincare/ie/ingredients/ergothioneine The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland. Ergothioneine gently helps the skin by neutralizing everyday stress, shielding against ultraviolet damage, and smoothing away redness, dryness, flaking, and fine lines while supporting lasting moisture, firmness, and natural barrier strength. This thoughtful ingredient suits almost all skin types and is commonly found in nourishing [serums](https://lovi.care/skincare/ie/ingredients/serum) designed for daily care. Because it layers easily, ergothioneine fits seamlessly into any existing skincare routine. [Free Radical Biology & Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26021820/) [ACS Applied Materials & Interfaces, 2024](https://pubmed.ncbi.nlm.nih.gov/38813785/) [International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40497421/) This page shows ergothioneine products with a Lovi page. For every product, and a routine built for your skin, use the Lovi app. ### Popular ergothioneine products - [The Ordinary Retinal 0.2% Emulsion](https://lovi.care/skincare/ie/p/the-ordinary/retinal-0-2-emulsion/for/oily-acne-prone-skin) — High fit — [€14.57 at Amazon](https://www.amazon.ie/dp/B0CZ5VG3L1?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1) - [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ie/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin) — High fit - [Paula's Choice 25% Vitamin C + Glutathione Clinical Serum](https://lovi.care/skincare/ie/p/paula-s-choice/25-vitamin-c-glutathione-clinical-serum/for/combination-skin) — High fit — [€73.00 at Amazon](https://www.amazon.ie/dp/B0CZ4BKT3T?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1) ### Other ergothioneine products - [The Ordinary Retinal 0.2% Emulsion](https://lovi.care/skincare/ie/p/the-ordinary/retinal-0-2-emulsion/for/oily-acne-prone-skin) — High fit — [€14.57 at Amazon](https://www.amazon.ie/dp/B0CZ5VG3L1?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1) - [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ie/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin) — High fit - [Paula's Choice 25% Vitamin C + Glutathione Clinical Serum](https://lovi.care/skincare/ie/p/paula-s-choice/25-vitamin-c-glutathione-clinical-serum/for/combination-skin) — High fit — [€73.00 at Amazon](https://www.amazon.ie/dp/B0CZ4BKT3T?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1) - [Elizabeth Arden Prevage Anti-Aging Eye Serum 2.0](https://lovi.care/skincare/ie/p/elizabeth-arden/prevage-anti-aging-eye-serum-2-0/for/mature-skin) — High fit — [€101.20 at Amazon](https://www.amazon.ie/dp/B00G4JPDJO?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1) ## What reviewers say about popular ergothioneine products The highlight reviewers mention most for each popular ergothioneine product on Lovi. - The Ordinary Retinal 0.2% Emulsion Improves skin texture ★4.3 · 2.4k+ reviews Yellow staining Fast absorption “skin feels smoother to the touch” [What people say about Retinal 0.2% Emulsion](https://lovi.care/skincare/ie/p/the-ordinary/retinal-0-2-emulsion/for/oily-acne-prone-skin) - Skinbetter Science Alto Advanced Defense and Repair Serum Elegant texture ★4.8 · 200+ reviews High price point Improves radiance “Feels lightweight and silky” [What people say about Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ie/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin) - Paula's Choice 25% Vitamin C + Glutathione Clinical Serum Effective brightening ★4.5 · 600+ reviews Elegant texture High price point “Discoloration almost gone” [What people say about 25% Vitamin C + Glutathione Clinical Serum](https://lovi.care/skincare/ie/p/paula-s-choice/25-vitamin-c-glutathione-clinical-serum/for/combination-skin) ## Questions and answers ### What does ergothioneine do for the skin? Ergothioneine helps protect the skin against UV and radiation damage by fighting free radicals, reducing oxidative stress, and supporting antioxidant defenses. It also helps improve skin hydration, elasticity, and barrier function while decreasing redness and signs of aging. [Free Radical Biology & Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26021820/) [ACS Applied Materials & Interfaces, 2024](https://pubmed.ncbi.nlm.nih.gov/38813785/) ### How do you use ergothioneine? Ergothioneine is used daily in targeted skincare regimens and dressings to help protect against skin damage from UV rays and treatments, while improving skin hydration and elasticity. [Free Radical Biology & Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26021820/) [ACS Applied Materials & Interfaces, 2024](https://pubmed.ncbi.nlm.nih.gov/38813785/) ### Should you use ergothioneine in the morning or at night? Ergothioneine helps protect skin from UV and oxidative damage when used as part of your routine. Studies show it supports antioxidant defenses and helps improve skin elasticity and hydration over time. [Free Radical Biology & Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26021820/) [Frontiers in Nutrition, 2026](https://pubmed.ncbi.nlm.nih.gov/42698538/) ### Can you use ergothioneine every day? Yes, you can use ergothioneine every day as it helps protect against skin damage and oxidative stress. Studies show it supports skin health, hydration, and elasticity when used regularly. [Free Radical Biology & Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26021820/) [ACS Applied Materials & Interfaces, 2024](https://pubmed.ncbi.nlm.nih.gov/38813785/) ### Does ergothioneine cause purging or irritation? Ergothioneine is unlikely to cause purging or irritation as it is known for its protective, antioxidant, and anti-inflammatory properties that help defend the skin against damage and oxidative stress. [Free Radical Biology & Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26021820/) [ACS Applied Materials & Interfaces, 2024](https://pubmed.ncbi.nlm.nih.gov/38813785/) ### Which skin types is ergothioneine best for? Ergothioneine is best for skin types dealing with environmental damage and aging, as it helps protect against UV and oxidative stress. It is found in popular products like The Ordinary [Retinal](https://lovi.care/skincare/ie/ingredients/retinal) 0.2% Emulsion, Skinbetter Science Alto Advanced Defense and Repair [Serum](https://lovi.care/skincare/ie/ingredients/serum), and Paula's Choice 25% [Vitamin C](https://lovi.care/skincare/ie/ingredients/vitamin-c) + [Glutathione](https://lovi.care/skincare/ie/ingredients/glutathione) Clinical Serum. [Free Radical Biology & Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26021820/) [Frontiers in Nutrition, 2026](https://pubmed.ncbi.nlm.nih.gov/42698538/) ## Research on ergothioneine - [Dermato-protective properties of ergothioneine through induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated Human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26021820/) Ergothioneine · Free Radical Biology & Medicine, 2015 - [Ergothioneine-Sodium Hyaluronate Dressing: A Promising Approach for Protecting against Radiation-Induced Skin Injury](https://pubmed.ncbi.nlm.nih.gov/38813785/) Ergothioneine · ACS Applied Materials & Interfaces, 2024 - [Preliminary evaluation of a comprehensive skincare regimen for enhancing skin health following advanced optimal pulse technology (AOPT) treatment](https://pubmed.ncbi.nlm.nih.gov/40497421/) Ergothioneine · International Journal of Cosmetic Science, 2025 - [Ergothioneine, collagen peptides, and sodium hyaluronate ameliorate facial skin aging via modulating oxidative stress, inflammation, and extracellular matrix homeostasis](https://pubmed.ncbi.nlm.nih.gov/42698538/) Ergothioneine · Frontiers in Nutrition, 2026 ## Brands with ergothioneine - Canadian skincare: [The Ordinary](https://lovi.care/skincare/ie/brands/the-ordinary) - American skincare: [Paula's Choice](https://lovi.care/skincare/ie/brands/paula-s-choice) - American skincare: [Skinbetter Science](https://lovi.care/skincare/ie/brands/skinbetter-science) - American skincare: [Elizabeth Arden](https://lovi.care/skincare/ie/brands/elizabeth-arden) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every ingredient with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this ingredient guide: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/ergothioneine - United Kingdom: https://lovi.care/skincare/uk/ingredients/ergothioneine - Ireland: https://lovi.care/skincare/ie/ingredients/ergothioneine (this page) - Germany: https://lovi.care/skincare/de/ingredients/ergothioneine - France: https://lovi.care/skincare/fr/ingredients/ergothioneine - Italy: https://lovi.care/skincare/it/ingredients/ergothioneine - Netherlands: https://lovi.care/skincare/nl/ingredients/ergothioneine - Spain: https://lovi.care/skincare/es/ingredients/ergothioneine - Canada: https://lovi.care/skincare/ca/ingredients/ergothioneine - Australia: https://lovi.care/skincare/au/ingredients/ergothioneine - Singapore: https://lovi.care/skincare/sg/ingredients/ergothioneine - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/ergothioneine - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/ergothioneine