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Copper and hexapeptide-9

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Copper and hexapeptide-9: keep them apart

Keep them apart

Use them on alternate nights because they cancel each other out when applied together. Combining these two active ingredients can cause them to react and make your routine less effective. You can simply switch to using one in the morning and the other at night, or use them on different days.

Copper products

Hexapeptide-9 products

Questions and answers

Can you use copper and hexapeptide-9 together?

Keep them apart and use them in alternating routines, as copper and hexapeptide-9 may react or become inactivated when combined. This separation helps protect your skin barrier and maintains the effectiveness of both ingredients.

Which goes first, copper or hexapeptide-9?

Keep copper and hexapeptide-9 apart in your routine because they may react when combined. Use them in alternating routines to prevent oxidation.

Are copper and hexapeptide-9 good for sensitive skin?

Copper and hexapeptide-9 are generally kept apart in the same routine because copper peptides may react with strong reducing agents or unstable antioxidants, potentially causing oxidation or inactivation. Lovi rates the fit for sensitive skin as Average when these ingredients are not separated.

Research on copper and hexapeptide-9

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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