# Neutrogena vs MAC

Page: https://lovi.care/skincare/ie/compare/neutrogena-vs-mac

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Neutrogena and MAC are two distinct beauty brands, with the former being an American skincare line founded in 1930 and the latter a Canadian label established in 1984. Neutrogena is known for moisturizers, sunscreens, cleansers, and toners featuring [glycerin](https://lovi.care/skincare/ie/ingredients/glycerin), [hyaluronic acid](https://lovi.care/skincare/ie/ingredients/hyaluronic-acid), and [dimethicone](https://lovi.care/skincare/ie/ingredients/dimethicone), which suit sensitive and dry skin best. Meanwhile, MAC is celebrated for reliable daily moisturizers and makeup removers that suit balanced skin best. While both offer gentle, thoughtfully formulated solutions for various skin concerns, they differ in their foundational ingredients and primary skin compatibility.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

[investor.kimberly-clark.com](https://www.investor.kimberly-clark.com/news-releases/news-release-details/kimberly-clark-completes-acquisition-kenvue-creating-preeminent) [en.wikipedia.org](https://en.wikipedia.org/wiki/Neutrogena) [investors.kenvue.com](https://investors.kenvue.com/financial-news/news-details/2025/Kimberly-Clark-to-Acquire-Kenvue-Creating-a-32-Billion-Global-Health-and-Wellness-Leader/default.aspx)

MAC is a Canadian skincare brand founded in 1984 and owned by The Estée Lauder Companies Inc. since 1994.

[elcompanies.com](https://www.elcompanies.com/en-gb/our-brands/mac) [en.wikipedia.org](https://en.wikipedia.org/wiki/Est%C3%A9e_Lauder_Companies)

This page compares some of the most popular Neutrogena and MAC products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg8df8456273).

### Popular Neutrogena vs MAC products

#### Neutrogena

- [Hydro Boost Water Gel](https://lovi.care/skincare/ie/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [€10.11 at Amazon](https://www.amazon.ie/dp/B01LZUCVV5?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/ie/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [€24.99 at Amazon](https://www.amazon.ie/dp/B005IHT94S?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/ie/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit — [€8.65 at Amazon](https://www.amazon.ie/dp/B087QX6CMQ?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Ultra Gentle Daily Cleanser](https://lovi.care/skincare/ie/p/neutrogena/ultra-gentle-daily-cleanser/for/mature-skin) — Superior fit — [€6.10 at Amazon](https://www.amazon.ie/dp/B0FX39SMK5?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Rapid Wrinkle Repair Regenerating Cream](https://lovi.care/skincare/ie/p/neutrogena/rapid-wrinkle-repair-regenerating-cream/for/mature-skin) — High fit — [€47.33 at Amazon](https://www.amazon.ie/dp/B0725JP4TN?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/ie/p/neutrogena/oil-free-eye-makeup-remover/for/dark-spots) — Superior fit
- [Retinol Regenerating Cream](https://lovi.care/skincare/ie/p/neutrogena/retinol-regenerating-cream/for/mature-skin) — Average fit
- [COLLAGEN BANK Moisturizer](https://lovi.care/skincare/ie/p/neutrogena/collagen-bank-moisturizer/for/dry-skin) — Average fit — [€15.90 at Amazon](https://www.amazon.ie/dp/B0FL2VB84J?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)

#### MAC

- [Hyper Real Serumizer](https://lovi.care/skincare/ie/p/mac/hyper-real-serumizer/for/dry-sensitive-skin) — High fit — [€72.91 at Amazon](https://www.amazon.ie/dp/B0BV14LWTN?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Mineralize Timecheck Lotion](https://lovi.care/skincare/ie/p/mac/mineralize-timecheck-lotion/for/dry-skin) — High fit
- [Hyper Real Fresh Canvas Cleansing Oil](https://lovi.care/skincare/ie/p/mac/hyper-real-fresh-canvas-cleansing-oil/for/dry-sensitive-skin) — High fit

## People Say

Neutrogena

MAC

- Lightweight hydration Mostly Mentioned Mostly Mentioned “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel” “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM” “absorbs quickly — MAC Hyper Real Serumizer” “Absorbs in a snap — MAC Mineralize Timecheck Lotion”
- Makeup compatibility and primer Rarely Noted Mostly Mentioned “foundation glides on — MAC Hyper Real Serumizer” “Sits beautifully under makeup — MAC Mineralize Timecheck Lotion” “Reduces appearance of pores — MAC Mineralize Timecheck Lotion” “Works well under makeup — Neutrogena HYDRO BOOST WATER CREAM”
- Gentle and fragrance-free formulas Often Mentioned Sometimes Noted “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser” “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser” “calms my acne prone skin — Neutrogena Ultra Gentle Daily Cleanser” “Does not cause breakouts — MAC Mineralize Timecheck Lotion”
- Cleansing and makeup removal Sometimes Noted Often Mentioned “Removes waterproof mascara completely without needing a separate remover. — MAC Hyper Real Fresh Canvas Cleansing Oil” “Emulsifies beautifully and rinses off without a greasy film. — MAC Hyper Real Fresh Canvas Cleansing Oil” “Leaves skin feeling soft and supple, never tight. — MAC Hyper Real Fresh Canvas Cleansing Oil” “dissolves stubborn waterproof mascara — Neutrogena Oil-Free Eye Makeup Remover”
- Radiant glow and appearance Rarely Noted Often Mentioned “lit-from-within look — MAC Hyper Real Serumizer” “hasn't caused a single breakout — Neutrogena Hydro Boost Water Gel”
- Anti-aging and skin texture Sometimes Noted Sometimes Noted “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream” “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream” “petal-soft skin — MAC Hyper Real Serumizer”
- Price and quantity value Sometimes Noted Mostly Mentioned “Jar is too small for the price — Neutrogena Hydro Boost Water Gel” “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM” “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream” “too expensive — MAC Hyper Real Serumizer”
- Insufficient moisture or efficacy Often Mentioned Sometimes Noted “Don't expect miracles — MAC Mineralize Timecheck Lotion” “Felt sticky to me — MAC Mineralize Timecheck Lotion” “leaves greasy film — Neutrogena Oil-Free Eye Makeup Remover”
- Skin and eye irritation Often Mentioned Sometimes Noted “caused acne — MAC Hyper Real Serumizer” “Stings if it accidentally gets into the eyes. — MAC Hyper Real Fresh Canvas Cleansing Oil” “burns my eyes terribly — Neutrogena Ultra Sheer Dry-Touch Sunscreen”
- Fragrance and scent issues Sometimes Noted Often Mentioned “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel” “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream” “has a weird plastic smell — Neutrogena Ultra Gentle Daily Cleanser” “scent is overpowering — MAC Hyper Real Serumizer”

## Questions and answers

### Neutrogena or MAC: which is better?

Neutrogena is better for gentle, fragrance-free formulas and value, while MAC is preferred for makeup compatibility and primer benefits. Lovi rates Neutrogena as a High or Superior fit for sensitive, dry, and mature skin types across the products on this page.

### What is the difference between Neutrogena and MAC?

Neutrogena offers a large range of mostly fragrance-free products that Lovi rates best for sensitive, dry, and mature skin, while MAC provides a smaller selection of scented items known for makeup compatibility and primers. Reviewers find that Neutrogena delivers better price and quantity value, whereas MAC tends to have a higher price point.

### Neutrogena or MAC: which moisturizer is better?

Neutrogena offers a wider variety of moisturizers with options like the Hydro Boost [Hyaluronic Acid](https://lovi.care/skincare/ie/ingredients/hyaluronic-acid) [Serum](https://lovi.care/skincare/ie/ingredients/serum) achieving a High fit for dry skin, whereas MAC features fewer choices like the Hyper Real Serumizer which has an Average fit for dry skin. Reviewers note that Neutrogena moisturizers are deeply hydrating, lightweight, and often acne-safe, while MAC products tend to have a higher price point and occasional sensitivity issues.

[Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, Neutrogena or MAC?

Neutrogena is more affordable than MAC, as MAC has a high price point while Neutrogena offers better price and quantity value.

### Which causes fewer breakouts, Neutrogena or MAC?

Neutrogena is generally better for acne-prone skin, as the products on this page include options with an acne-safe and gentle fit like the Ultra Gentle Daily Cleanser, whereas MAC features fewer products overall and has more reports of skin sensitivity.

### Which brand has more fragrance-free skincare products, Neutrogena or MAC?

Neutrogena has significantly more fragrance-free skincare products, with 35 out of 39 products on this page listing no fragrance, while MAC has none.

### How do the founding years and corporate owners of Neutrogena and MAC compare?

Neutrogena was founded in the United States in 1930 and is owned by Kimberly-Clark Corporation, while MAC was founded in Canada in 1984 and is owned by The Estée Lauder Companies Inc.

### What are the main skin types that Neutrogena's brand-focused routines fit best?

Neutrogena's brand-focused routines fit sensitive skin, dry skin, and mature skin best. The products on this page help deliver deep hydration to these skin types.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Sodium hyaluronate · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate](https://pubmed.ncbi.nlm.nih.gov/11766131/) Benzyl alcohol · International Journal of Toxicology, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Vitamin b5, Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf extract · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Final report on the safety assessment of BHT(1)](https://pubmed.ncbi.nlm.nih.gov/12396675/) Bht · International Journal of Toxicology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol, Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice, Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica seed oil · Journal of Ethnopharmacology, 2007
- [Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro](https://pubmed.ncbi.nlm.nih.gov/26087228/) Plukenetia volubilis seed oil · Journal of Ethnopharmacology, 2015
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic Dermatology, 2007
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine, Neoglucosamine · The British Journal of Dermatology, 2010
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Vitamin b5, Panthenol · The Journal of Dermatological Treatment, 2017
- [Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation](https://pubmed.ncbi.nlm.nih.gov/28936777/) Hydration complex · Archives of Dermatological Research, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Self-Assembled Cubic Liquid Crystalline Nanoparticles for Transdermal Delivery of Paeonol](https://pubmed.ncbi.nlm.nih.gov/26517086/) Paeonia albiflora flower extract · Medical Science Monitor, 2015
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)](https://pubmed.ncbi.nlm.nih.gov/19112586/) Chrysanthemum parthenium flower leaf stem juice · Inflammopharmacology, 2009
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Paeonia albiflora flower extract · Molecules, 2023
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [Preparation and evaluation of benzalkonium chloride hand sanitizer as a potential alternative for alcohol-based hand gels](https://pubmed.ncbi.nlm.nih.gov/34408542/) Benzalkonium chloride · Saudi Pharmaceutical Journal, 2021
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Hydration complex · Molecules, 2021
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Efficacy and tolerability of the investigational topical cream SD-101 (6% allantoin) in patients with epidermolysis bullosa: a phase 3, randomized, double-blind, vehicle-controlled trial (ESSENCE study)](https://pubmed.ncbi.nlm.nih.gov/32576219/) Allantoin · Orphanet Journal of Rare Diseases, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Grapefruit extract · Frontiers in Chemistry, 2024
- [Subclinical cutaneous inflammation remained after permeability barrier disruption enhances UV sensitivity by altering ER stress responses and topical pseudoceramide prevents them](https://pubmed.ncbi.nlm.nih.gov/28631090/) Ceramide ng · Archives of Dermatological Research, 2017
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Parthenolide-depleted Feverfew (Tanacetum parthenium) protects skin from UV irradiation and external aggression](https://pubmed.ncbi.nlm.nih.gov/18071724/) Chrysanthemum parthenium flower leaf stem juice · Archives of Dermatological Research, 2008
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin](https://pubmed.ncbi.nlm.nih.gov/16676123/) Paeonia albiflora flower extract · Journal of Cosmetic Science, 2006
- [Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/19622017/) Oxybenzone, Oxybenzone-free formula · Journal of Microencapsulation, 2010
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine, Neoglucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Axillary hyperhidrosis. Local treatment with aluminium-chloride hexahydrate 25% in absolute ethanol with and without supplementary treatment with triethanolamine](https://pubmed.ncbi.nlm.nih.gov/2449022/) Triethanolamine · Acta Dermato-venereologica, 1988
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Oxybenzone-free formula · International Journal of Pharmaceutics, 2019
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- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Rates of allergic sensitization and irritation to oxybenzone-containing sunscreen products: a quantitative meta-analysis of 64 exaggerated use studies](https://pubmed.ncbi.nlm.nih.gov/18717962/) Helioplex technology, Helioplex · Photodermatology, Photoimmunology & Photomedicine, 2008
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [A new formula for a mild body cleanser: sodium laureth sulphate supplemented with sodium laureth carboxylate and lauryl glucoside](https://pubmed.ncbi.nlm.nih.gov/24617572/) Lauryl glucoside · International Journal of Cosmetic Science, 2014
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Vitamin b5, Panthenol · Journal of Cosmetic Dermatology, 2025
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [Instrumental, clinical and subjective evaluation of the efficacy of a cosmetic treatment for home use](https://pubmed.ncbi.nlm.nih.gov/30040516/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic and Laser Therapy, 2019
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
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## The brands

- American skincare: [Neutrogena](https://lovi.care/skincare/ie/brands/neutrogena)
- Canadian skincare: [MAC](https://lovi.care/skincare/ie/brands/mac)

## More comparisons

- [SKIN1004 vs Neutrogena](https://lovi.care/skincare/ie/compare/skin1004-vs-neutrogena)
- [SKIN1004 vs MAC](https://lovi.care/skincare/ie/compare/skin1004-vs-mac)
- [Anua vs Neutrogena](https://lovi.care/skincare/ie/compare/anua-vs-neutrogena)
- [Anua vs MAC](https://lovi.care/skincare/ie/compare/anua-vs-mac)
- [Medicube vs Neutrogena](https://lovi.care/skincare/ie/compare/medicube-vs-neutrogena)
- [Medicube vs MAC](https://lovi.care/skincare/ie/compare/medicube-vs-mac)
- [The Ordinary vs Neutrogena](https://lovi.care/skincare/ie/compare/the-ordinary-vs-neutrogena)
- [The Ordinary vs MAC](https://lovi.care/skincare/ie/compare/the-ordinary-vs-mac)
- [Beauty of Joseon vs Neutrogena](https://lovi.care/skincare/ie/compare/beauty-of-joseon-vs-neutrogena)
- [Beauty of Joseon vs MAC](https://lovi.care/skincare/ie/compare/beauty-of-joseon-vs-mac)
- [COSRX vs Neutrogena](https://lovi.care/skincare/ie/compare/cosrx-vs-neutrogena)
- [COSRX vs MAC](https://lovi.care/skincare/ie/compare/cosrx-vs-mac)
- [CeraVe vs Neutrogena](https://lovi.care/skincare/ie/compare/cerave-vs-neutrogena)
- [CeraVe vs MAC](https://lovi.care/skincare/ie/compare/cerave-vs-mac)
- [La Roche-Posay vs Neutrogena](https://lovi.care/skincare/ie/compare/la-roche-posay-vs-neutrogena)
- [La Roche-Posay vs MAC](https://lovi.care/skincare/ie/compare/la-roche-posay-vs-mac)
- [Dr. Althea vs Neutrogena](https://lovi.care/skincare/ie/compare/dr-althea-vs-neutrogena)
- [Dr. Althea vs MAC](https://lovi.care/skincare/ie/compare/dr-althea-vs-mac)
- [Some By Mi vs Neutrogena](https://lovi.care/skincare/ie/compare/some-by-mi-vs-neutrogena)
- [Some By Mi vs MAC](https://lovi.care/skincare/ie/compare/some-by-mi-vs-mac)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/neutrogena-vs-mac
- United Kingdom: https://lovi.care/skincare/uk/compare/neutrogena-vs-mac
- Ireland: https://lovi.care/skincare/ie/compare/neutrogena-vs-mac (this page)
- Germany: https://lovi.care/skincare/de/compare/neutrogena-vs-mac
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- Italy: https://lovi.care/skincare/it/compare/neutrogena-vs-mac
- Netherlands: https://lovi.care/skincare/nl/compare/neutrogena-vs-mac
- Spain: https://lovi.care/skincare/es/compare/neutrogena-vs-mac
- Canada: https://lovi.care/skincare/ca/compare/neutrogena-vs-mac
- Australia: https://lovi.care/skincare/au/compare/neutrogena-vs-mac
- Singapore: https://lovi.care/skincare/sg/compare/neutrogena-vs-mac
- Saudi Arabia: https://lovi.care/skincare/sa/compare/neutrogena-vs-mac
- United Arab Emirates: https://lovi.care/skincare/ae/compare/neutrogena-vs-mac