# Mesoestetic vs Rilastil

Page: https://lovi.care/skincare/ie/compare/mesoestetic-vs-rilastil

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Mesoestetic and Rilastil are esteemed European skincare houses known for their targeted [serums](https://lovi.care/skincare/ie/ingredients/serum) and meticulously crafted formulas that elevate daily routines. The Spanish brand founded in 1984 suits mature, sensitive, and uneven skin best, while the second option is especially cherished for sensitive, dry, and mature skin types due to a deeply nourishing approach. For stubborn blemishes, the former relies on the Cosmelan 2, and the latter features the Acnestil as its standout solution for acne-prone skin. Both labels differ primarily in their precise origins and specific ingredient compositions, yet each careful application delivers balanced nourishment to support long-term skin health and restore daily comfort.

Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L..

[mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk)

This page compares some of the most popular Mesoestetic and Rilastil products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg8f7a003b86).

### Popular Mesoestetic vs Rilastil products

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/ie/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

#### Rilastil

- [Acnestil](https://lovi.care/skincare/ie/p/rilastil/acnestil/for/oily-skin) — Average fit

### Mesoestetic vs Rilastil [serums](https://lovi.care/skincare/ie/ingredients/serum) and treatments

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/ie/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

#### Rilastil

- [Acnestil](https://lovi.care/skincare/ie/p/rilastil/acnestil/for/oily-skin) — Average fit

## Questions and answers

### Mesoestetic or Rilastil: which is better?

Neither brand is universally better, as both Mesoestetic and Rilastil achieve only Average Lovi fit levels for the products on this page across common skin types. Every product from both brands on this page lists no fragrance in its ingredients.

### What is the difference between Mesoestetic and Rilastil?

Mesoestetic and Rilastil are both skincare brands that feature no fragrance in the products on this page. For oily and acne-prone skin, Lovi gives both Mesoestetic's Cosmelan 2 and Rilastil's Acnestil an Average fit level.

### Which is more affordable, Mesoestetic or Rilastil?

The page facts do not provide pricing information for Mesoestetic or Rilastil, so we cannot determine which brand is more affordable.

### Which causes fewer breakouts, Mesoestetic or Rilastil?

Both Mesoestetic and Rilastil offer products on this page that reach an average Lovi fit level for acne-prone skin, meaning they help with breakouts. Every product on this page from both brands lists no fragrance in its ingredients.

### Which skincare brand has been around longer, Mesoestetic or Rilastil?

Rilastil has been around longer, having been founded in 1972 compared to Mesoestetic, which was founded in 1984.

### Where were Mesoestetic and Rilastil founded?

Mesoestetic was founded in Spain, while the origin location for Rilastil is not available on this page.

### Do any of the Mesoestetic or Rilastil products listed on this page contain fragrance?

Every product from Mesoestetic and Rilastil listed on this page lists no fragrance in its ingredients.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022

## The brands

- Spanish skincare: [Mesoestetic](https://lovi.care/skincare/ie/brands/mesoestetic)
- Skincare: [Rilastil](https://lovi.care/skincare/ie/brands/rilastil)

## More comparisons

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- [Medicube vs Rilastil](https://lovi.care/skincare/ie/compare/medicube-vs-rilastil)
- [The Ordinary vs Mesoestetic](https://lovi.care/skincare/ie/compare/the-ordinary-vs-mesoestetic)
- [The Ordinary vs Rilastil](https://lovi.care/skincare/ie/compare/the-ordinary-vs-rilastil)
- [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/ie/compare/beauty-of-joseon-vs-mesoestetic)
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- [COSRX vs Mesoestetic](https://lovi.care/skincare/ie/compare/cosrx-vs-mesoestetic)
- [COSRX vs Rilastil](https://lovi.care/skincare/ie/compare/cosrx-vs-rilastil)
- [CeraVe vs Mesoestetic](https://lovi.care/skincare/ie/compare/cerave-vs-mesoestetic)
- [CeraVe vs Rilastil](https://lovi.care/skincare/ie/compare/cerave-vs-rilastil)
- [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/ie/compare/la-roche-posay-vs-mesoestetic)
- [La Roche-Posay vs Rilastil](https://lovi.care/skincare/ie/compare/la-roche-posay-vs-rilastil)
- [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/ie/compare/dr-althea-vs-mesoestetic)
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- [Some By Mi vs Mesoestetic](https://lovi.care/skincare/ie/compare/some-by-mi-vs-mesoestetic)
- [Some By Mi vs Rilastil](https://lovi.care/skincare/ie/compare/some-by-mi-vs-rilastil)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/mesoestetic-vs-rilastil
- United Kingdom: https://lovi.care/skincare/uk/compare/mesoestetic-vs-rilastil
- Ireland: https://lovi.care/skincare/ie/compare/mesoestetic-vs-rilastil (this page)
- Germany: https://lovi.care/skincare/de/compare/mesoestetic-vs-rilastil
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- Italy: https://lovi.care/skincare/it/compare/mesoestetic-vs-rilastil
- Netherlands: https://lovi.care/skincare/nl/compare/mesoestetic-vs-rilastil
- Spain: https://lovi.care/skincare/es/compare/mesoestetic-vs-rilastil
- Canada: https://lovi.care/skincare/ca/compare/mesoestetic-vs-rilastil
- Australia: https://lovi.care/skincare/au/compare/mesoestetic-vs-rilastil
- Singapore: https://lovi.care/skincare/sg/compare/mesoestetic-vs-rilastil
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