# Good Molecules vs Clinique

Page: https://lovi.care/skincare/ie/compare/good-molecules-vs-clinique

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Good Molecules and Clinique are American skincare brands known for their thoughtful ranges of targeted [serums](https://lovi.care/skincare/ie/ingredients/serum), nourishing moisturizers, eye products, and gentle exfoliants. Both brands suit dry skin and oily skin best, utilizing key ingredients like [glycerin](https://lovi.care/skincare/ie/ingredients/glycerin) and [hyaluronic acid](https://lovi.care/skincare/ie/ingredients/hyaluronic-acid) to improve hydration and restore barrier function. While the younger brand relies on targeted formulations, the older enterprise incorporates [caffeine](https://lovi.care/skincare/ie/ingredients/caffeine) to protect against UV radiation and prevent excessive fat accumulation. These distinct approaches offer unique solutions for addressing acne-prone skin, dark spots, and mature concerns.

Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..

[beautymatter.com](https://beautymatter.com/articles/aria-growth-partners-makes-investment-in-good-molecules) [goodmolecules.com](https://www.goodmolecules.com/about) [pitchbook.com](https://pitchbook.com/profiles/company/458272-45) [preqin.com](https://www.preqin.com/data/profile/asset/good-molecules--llc-/802471)

Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Clinique) [elcompanies.com](https://www.elcompanies.com/en/who-we-are/our-heritage) [businesswire.com](https://www.businesswire.com/news/home/20261019083802/en/The-Este-Lauder-Companies-Appoints-Krista-Lee-Berger-Senior-Vice-President-Global-Marketing-Clinique) [glossy.co](https://www.glossy.co/beauty/glossy-pop-newsletter-clinique-launches-first-ever-creator-led-campaign/)

This page compares some of the most popular Good Molecules and Clinique products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgd32d52a565).

### Popular Good Molecules vs Clinique products

#### Good Molecules

- [Discoloration Correcting Serum](https://lovi.care/skincare/ie/p/good-molecules/discoloration-correcting-serum/for/dry-skin) — High fit — [€27.00 at Amazon](https://www.amazon.ie/dp/B08RJ4ZHXJ?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Acid Serum](https://lovi.care/skincare/ie/p/good-molecules/hyaluronic-acid-serum/for/dry-skin) — Superior fit — [€21.99 at Amazon](https://www.amazon.ie/dp/B08TM8DLFJ?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Gentle Retinol Cream](https://lovi.care/skincare/ie/p/good-molecules/gentle-retinol-cream/for/mature-skin) — High fit — [€21.33 at Amazon](https://www.amazon.ie/dp/B09BST7MMP?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Niacinamide Serum](https://lovi.care/skincare/ie/p/good-molecules/niacinamide-serum/for/oily-skin) — Average fit — [€18.88 at Amazon](https://www.amazon.ie/dp/B08R994Q1L?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Niacinamide Brightening Toner](https://lovi.care/skincare/ie/p/good-molecules/niacinamide-brightening-toner/for/dry-skin) — High fit
- [PIMPLE PATCHES](https://lovi.care/skincare/ie/p/good-molecules/pimple-patches/for/acne-prone-skin) — Average fit
- [Yerba Mate Wake Up Eye Gel](https://lovi.care/skincare/ie/p/good-molecules/yerba-mate-wake-up-eye-gel/for/mature-skin) — Superior fit — [€12.39 at Amazon](https://www.amazon.ie/dp/B091NJQ29P?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Lightweight Daily Moisturizer](https://lovi.care/skincare/ie/p/good-molecules/lightweight-daily-moisturizer/for/dry-skin) — Superior fit

#### Clinique

- [moisture surge](https://lovi.care/skincare/ie/p/clinique/moisture-surge/for/sensitive-skin) — High fit
- [Take The Day Off Cleansing Balm](https://lovi.care/skincare/ie/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [€19.40 at Amazon](https://www.amazon.ie/dp/B07F1LRBCF?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Lotion+](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-lotion/for/dry-skin) — Average fit — [€5.70 at Notino](https://www.notino.ie/clinique/3-steps-dramatically-different-moisturizing-lotion-for-very-dry-to-dry-combination-skin/p-67230/)
- [All About Eyes](https://lovi.care/skincare/ie/p/clinique/all-about-eyes/for/dry-skin) — High fit — [€58.00 at Amazon](https://www.amazon.ie/dp/B002SPYL7S?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [€17.50 at Notino](https://www.notino.ie/clinique/3-steps-dramatically-different-moisturizing-gel-for-combination-oily-to-oily-skin/p-68905/)
- [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/ie/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit
- [Moisture Surge Overnight Mask](https://lovi.care/skincare/ie/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [€52.58 at Amazon](https://www.amazon.ie/dp/B0FGG612LR?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- [Clarifying Lotion 2](https://lovi.care/skincare/ie/p/clinique/clarifying-lotion-2/for/oily-acne-prone-skin) — Average fit — [€27.25 at Amazon](https://www.amazon.ie/dp/B01FBWEORQ?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)

## People Say

Good Molecules

Clinique

- Gentle and Sensitive-Skin Friendly Often Mentioned Mostly Mentioned “never irritated my eyes — Clinique All About Eyes” “No stinging eyes — Clinique Take The Day Off Cleansing Balm” “cools the heat in my cheeks — Clinique Redness Solutions Daily Relief Cream” “no skin purging — Good Molecules Gentle Retinol Cream”
- Lightweight and Fast-Absorbing Texture Mostly Mentioned Mostly Mentioned “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum” “practically invisible on skin — Good Molecules PIMPLE PATCHES” “sinks in immediately — Clinique moisture surge” “sinks in instantly — Clinique Dramatically Different Moisturizing Gel”
- Affordable Price and Value Mostly Mentioned Rarely Noted “best value for money — Good Molecules Hyaluronic Acid Serum” “great value — Good Molecules Niacinamide Serum” “lasts forever — Clinique all about clean”
- Hydration, Plumping, and Glow Mostly Mentioned Often Mentioned “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum” “Skin feels bouncy — Good Molecules Super Peptide Serum” “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum” “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
- Skin Texture and Pore Improvements Often Mentioned Sometimes Noted “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment” “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder” “smoother skin — Good Molecules Niacinamide Serum” “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- Fragrance-Free and Gentle Cleansing Not noted Often Mentioned “gentle enough for everyday — Clinique 7 Day Scrub Cream Rinse-Off Formula” “You will see the dirt with one wipe — Clinique Clarifying Lotion 2” “No strong scent — Clinique Take The Day Off Cleansing Balm”
- Causes Breakouts Sometimes Noted Sometimes Noted “face broke out everywhere — Good Molecules Discoloration Correcting Serum” “gave me little white bumps — Good Molecules Niacinamide Serum” “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+” “gave me tiny bumps — Clinique moisture surge”
- Unpleasant Texture, Soapy, or Waxy Residue Sometimes Noted Sometimes Noted “hard to rinse off — Clinique 7 Day Scrub Cream Rinse-Off Formula” “feels sticky to the touch — Clinique moisture surge” “Left an oily film on my T-zone — Clinique Dramatically Different Moisturizing Lotion+” “sticky to the touch — Good Molecules Niacinamide Brightening Toner”
- High Price for Size and Value Not noted Often Mentioned “jar is too small for the cost — Clinique moisture surge”

### Good Molecules vs Clinique routines for dry skin

#### Good Molecules-focused routine

- Cleanser: [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/ie/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [€14.68 at Amazon](https://www.amazon.ie/dp/B07C5XPXDC?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ie/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — [€14.28 at Amazon](https://www.amazon.ie/dp/B089SCWPJR?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hyaluronic Acid Serum](https://lovi.care/skincare/ie/p/good-molecules/hyaluronic-acid-serum/for/dry-skin) — Superior fit — [€21.99 at Amazon](https://www.amazon.ie/dp/B08TM8DLFJ?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/ie/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [€32.81 at Amazon](https://www.amazon.ie/dp/B00JJZN1HG?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ie/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€16.25 at Amazon](https://www.amazon.ie/dp/B084Q16G8D?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Discoloration Correcting Serum](https://lovi.care/skincare/ie/p/good-molecules/discoloration-correcting-serum/for/dry-skin) — High fit — [€27.00 at Amazon](https://www.amazon.ie/dp/B08RJ4ZHXJ?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Mediheal Watermide Essential Mask](https://lovi.care/skincare/ie/p/mediheal/watermide-essential-mask/for/dry-skin) — Superior fit — [€28.40 at Amazon](https://www.amazon.ie/dp/B00JE7TEES?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [all about clean](https://lovi.care/skincare/ie/p/clinique/all-about-clean/for/dry-skin) — Warning fit — [€30.00 at Amazon](https://www.amazon.ie/dp/B00BNAQDVG?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ie/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — [€14.28 at Amazon](https://www.amazon.ie/dp/B089SCWPJR?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Smart Clinical Repair Lifting Face + Neck Cream](https://lovi.care/skincare/ie/p/clinique/smart-clinical-repair-lifting-face-neck-cream/for/dry-skin) — High fit — [€78.09 at Amazon](https://www.amazon.ie/dp/B0CHXGY211?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/ie/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [€32.81 at Amazon](https://www.amazon.ie/dp/B00JJZN1HG?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/ie/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [€19.40 at Amazon](https://www.amazon.ie/dp/B07F1LRBCF?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Even Better Clinical Dark Spot Corrector](https://lovi.care/skincare/ie/p/clinique/even-better-clinical-dark-spot-corrector/for/dry-skin) — Average fit — Evening · Once a week
- Nourishing Mask: [Moisture Surge Overnight Mask](https://lovi.care/skincare/ie/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [€52.58 at Amazon](https://www.amazon.ie/dp/B0FGG612LR?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 98% fit](https://lovi.care/skincare/ie/skin/dry-skin)

### Good Molecules vs Clinique routines for oily skin

#### Good Molecules-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ie/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€21.45 at Amazon](https://www.amazon.ie/dp/B07C5XD33D?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ie/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€19.99 at Amazon](https://www.amazon.ie/dp/B08125WDCF?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hyaluronic Acid Serum](https://lovi.care/skincare/ie/p/good-molecules/hyaluronic-acid-serum/for/oily-skin) — High fit — [€21.99 at Amazon](https://www.amazon.ie/dp/B08TM8DLFJ?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/ie/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [€15.64 at Amazon](https://www.amazon.ie/dp/B0BT6VDJ5M?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/ie/p/pyunkang-yul/deep-cleansing-oil/for/oily-skin) — Superior fit — [€22.67 at Amazon](https://www.amazon.ie/dp/B08QTT1QBX?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/ie/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€34.00 at Amazon](https://www.amazon.ie/dp/B07RWL29GF?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Overnight Exfoliating Treatment](https://lovi.care/skincare/ie/p/good-molecules/overnight-exfoliating-treatment/for/oily-skin) — Superior fit — [€18.50 at Amazon](https://www.amazon.ie/dp/B08TMDRF1L?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ie/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€76.00 at Amazon](https://www.amazon.ie/dp/B071ZBJPH7?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Dr. Sebagh Deep Exfoliating Mask](https://lovi.care/skincare/ie/p/dr-sebagh/deep-exfoliating-mask/for/oily-skin) — Superior fit — [€82.85 at Amazon](https://www.amazon.ie/dp/B003E71NPC?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [Redness Solutions Soothing Cleanser](https://lovi.care/skincare/ie/p/clinique/redness-solutions-soothing-cleanser/for/oily-skin) — Average fit — [€31.05 at Lookfantastic](https://www.lookfantastic.ie/p/clinique-clinique-redness-solutionssoothing-cleanser-for-unisex-0/11144770/) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ie/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€19.99 at Amazon](https://www.amazon.ie/dp/B08125WDCF?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [€17.50 at Notino](https://www.notino.ie/clinique/3-steps-dramatically-different-moisturizing-gel-for-combination-oily-to-oily-skin/p-68905/) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/ie/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [€15.64 at Amazon](https://www.amazon.ie/dp/B0BT6VDJ5M?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/ie/p/clinique/take-the-day-off-cleansing-balm/for/oily-skin) — Low fit — [€19.40 at Amazon](https://www.amazon.ie/dp/B07F1LRBCF?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Clarifying Lotion 2](https://lovi.care/skincare/ie/p/clinique/clarifying-lotion-2/for/oily-skin) — Average fit — [€27.25 at Amazon](https://www.amazon.ie/dp/B01FBWEORQ?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Even Better Clinical Dark Spot Corrector](https://lovi.care/skincare/ie/p/clinique/even-better-clinical-dark-spot-corrector/for/oily-skin) — High fit — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ie/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€76.00 at Amazon](https://www.amazon.ie/dp/B071ZBJPH7?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Dr. Sebagh Deep Exfoliating Mask](https://lovi.care/skincare/ie/p/dr-sebagh/deep-exfoliating-mask/for/oily-skin) — Superior fit — [€82.85 at Amazon](https://www.amazon.ie/dp/B003E71NPC?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 96% fit](https://lovi.care/skincare/ie/skin/oily-skin)

### Good Molecules vs Clinique routines for combination skin

#### Good Molecules-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ie/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [€56.86 at Amazon](https://www.amazon.ie/dp/B00AU9EBTC?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/ie/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€115.30 at Amazon](https://www.amazon.ie/dp/B0CY5LW9DY?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hyaluronic Acid Serum](https://lovi.care/skincare/ie/p/good-molecules/hyaluronic-acid-serum/for/combination-skin) — High fit — [€21.99 at Amazon](https://www.amazon.ie/dp/B08TM8DLFJ?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/ie/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — [€22.67 at Amazon](https://www.amazon.ie/dp/B08QTT1QBX?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ie/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€22.99 at Amazon](https://www.amazon.ie/dp/B0FNRTX91F?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Overnight Exfoliating Treatment](https://lovi.care/skincare/ie/p/good-molecules/overnight-exfoliating-treatment/for/combination-skin) — Superior fit — [€18.50 at Amazon](https://www.amazon.ie/dp/B08TMDRF1L?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ie/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€76.00 at Amazon](https://www.amazon.ie/dp/B071ZBJPH7?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Sand & Sky Australian Pink Clay Porefining Face Mask](https://lovi.care/skincare/ie/p/sand-and-sky/australian-pink-clay-porefining-face-mask/for/combination-skin) — High fit — [€48.22 at Amazon](https://www.amazon.ie/dp/B076Z6PVVQ?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [all about clean](https://lovi.care/skincare/ie/p/clinique/all-about-clean/for/combination-skin) — Low fit — [€30.00 at Amazon](https://www.amazon.ie/dp/B00BNAQDVG?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/ie/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€115.30 at Amazon](https://www.amazon.ie/dp/B0CY5LW9DY?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/combination-skin) — Average fit — [€17.50 at Notino](https://www.notino.ie/clinique/3-steps-dramatically-different-moisturizing-gel-for-combination-oily-to-oily-skin/p-68905/) — Morning · Evening · Once a week
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/ie/p/clinique/take-the-day-off-cleansing-balm/for/combination-skin) — Low fit — [€19.40 at Amazon](https://www.amazon.ie/dp/B07F1LRBCF?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Clarifying Lotion 2](https://lovi.care/skincare/ie/p/clinique/clarifying-lotion-2/for/combination-skin) — Average fit — [€27.25 at Amazon](https://www.amazon.ie/dp/B01FBWEORQ?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Even Better Clinical Dark Spot Corrector](https://lovi.care/skincare/ie/p/clinique/even-better-clinical-dark-spot-corrector/for/combination-skin) — Average fit — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ie/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€76.00 at Amazon](https://www.amazon.ie/dp/B071ZBJPH7?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Sand & Sky Australian Pink Clay Porefining Face Mask](https://lovi.care/skincare/ie/p/sand-and-sky/australian-pink-clay-porefining-face-mask/for/combination-skin) — High fit — [€48.22 at Amazon](https://www.amazon.ie/dp/B076Z6PVVQ?tag=lovi-care-web-routine08-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/ie/skin/combination-skin)

## Questions and answers

### Good Molecules or Clinique: which is better?

Good Molecules offers better value and superior routine fits across nearly all skin types, while Clinique is noted for being particularly gentle and friendly for sensitive skin. Both brands provide fragrance-free products on the products on this page.

### What is the difference between Good Molecules and Clinique?

Good Molecules offers better affordability and higher overall fit across most skin types on this page, while Clinique is noted for being especially gentle and sensitive-skin friendly. Both brands provide fragrance-free options.

### Good Molecules or Clinique for dry skin?

Good Molecules is the better choice for dry skin, achieving a Superior routine fit compared to Clinique's High fit level. The products on this page help provide hydration, with key ingredients like [hyaluronic acid](https://lovi.care/skincare/ie/ingredients/hyaluronic-acid) supporting skin quality.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Good Molecules or Clinique: which cleanser is better?

Good Molecules offers better-rated cleansers on this page, with the Hydrating Facial Cleansing Gel achieving a High Lovi fit level for dry and sensitive skin types. In comparison, Clinique includes options like all about clean, which receives lower fit ratings and warnings for certain skin types. Both brands formulate their products on this page to be entirely fragrance-free.

### Which is more affordable, Good Molecules or Clinique?

Good Molecules is more affordable than Clinique and offers great value [serums](https://lovi.care/skincare/ie/ingredients/serum) and moisturizers. Reviewers note that Clinique has a high price point, while Good Molecules is known for providing budget-friendly skincare options.

### Good Molecules or Clinique: which is better for improving skin texture and reducing dark spots?

Good Molecules does better for skin texture and dark spot improvements compared to Clinique. Reviewers note that Good Molecules helps fade dark spots and improves skin texture.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Good Molecules or Clinique: which brand offers better hydration, plumping, and glow effects?

Good Molecules offers better hydration, plumping, and glow effects, as reviewers note it excels in providing hydration and a radiant finish compared to Clinique. Hyaluronic acid helps improve skin quality and hydration across the products on this page.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Good Molecules or Clinique: which brand provides a better routine fit for mature skin?

Good Molecules provides a Superior routine fit for mature skin, whereas Clinique provides a High routine fit. Both brands offer products containing ingredients that help support skin quality and combat signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Archives of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17515510/)

### Good Molecules or Clinique for oily skin?

Good Molecules is a better fit for oily skin, offering a Superior routine fit compared to Clinique's High fit on this page. Reviewers frequently note Good Molecules for its affordable and great value serums as well as oil-controlling benefits.

### Good Molecules or Clinique: which moisturizer is better?

Good Molecules offers better moisturizer options, with routines rated Superior for dry skin compared to Clinique's High fit. Reviewers note that Good Molecules provides affordable and hydrating moisturizers.

### Good Molecules or Clinique for sensitive skin?

Good Molecules is a better choice for sensitive skin because its products have a Lovi fit level of Superior for that skin type. Clinique also offers gentle products on this page, but Good Molecules is rated higher overall for sensitive skin routines.

### Good Molecules or Clinique for acne-prone skin?

Good Molecules is a better fit for acne-prone skin, achieving a Superior routine fit compared to Clinique's Average fit level. Reviewers mention that the products on this page help fade dark spots and improve skin texture.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology](https://pubmed.ncbi.nlm.nih.gov/19169201/) Squalene · Molecules, 2009
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Micro-acid complex · Journal of Dermatological Science, 2017
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Protecting skin photoaging by NF-kappaB inhibitor](https://pubmed.ncbi.nlm.nih.gov/20540695/) Magnolia officinalis bark extract · Current Drug Metabolism, 2010
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Effect of fermentation time on the content of bioactive compounds with cosmetic and dermatological properties in Kombucha Yerba Mate extracts](https://pubmed.ncbi.nlm.nih.gov/34552134/) Ilex paraguariensis leaf extract · Scientific Reports, 2021
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf water, Aloe barbadensis · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Anti-acne vulgaris effects of chlorogenic acid by anti-inflammatory activity and lipogenesis inhibition](https://pubmed.ncbi.nlm.nih.gov/33433016/) Ilex paraguariensis leaf extract · Experimental Dermatology, 2021
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Ascorbic acid powder · Journal of Cosmetic Dermatology, 2020
- [A double-blind, placebo-controlled randomized trial of Serratulae quinquefoliae folium, a new source of β-arbutin, in selected skin hyperpigmentations](https://pubmed.ncbi.nlm.nih.gov/26119285/) Arbutin · Journal of Cosmetic Dermatology, 2015
- [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Licorice root extract · Experimental Dermatology, 2015
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Effect of 30% Supramolecular Salicylic Acid Peel on Skin Microbiota and Inflammation in Patients with Moderate-to-Severe Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/36350527/) Micro-acid complex · Dermatology and Therapy, 2023
- [Systematic Study of Resveratrol Nanoliposomes Transdermal Delivery System for Enhancing Anti-Aging and Skin-Brightening Efficacy](https://pubmed.ncbi.nlm.nih.gov/36985709/) Polygonum cuspidatum root extract · Molecules, 2023
- [Role of Resveratrol in Regulating Cutaneous Functions](https://pubmed.ncbi.nlm.nih.gov/32382280/) Polygonum cuspidatum root extract · Evidence-based Complementary and Alternative Medicine, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB](https://pubmed.ncbi.nlm.nih.gov/17346696/) Magnolia officinalis bark extract · European Journal of Pharmacology, 2007
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2021
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results](https://pubmed.ncbi.nlm.nih.gov/39810881/) Probiotic technology · Journal of Experimental Pharmacology, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid, Micro-acid complex · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil](https://pubmed.ncbi.nlm.nih.gov/31957954/) Avocado oil · Journal of Cosmetic Dermatology, 2020
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Ilex paraguariensis extract · Frontiers in Chemistry, 2024
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Evaluating the Safety and Efficacy of a Topical Formulation Containing Epidermal Growth Factor, Tranexamic Acid, Vitamin C, Arbutin, Niacinamide and Other Ingredients as Hydroquinone 4% Alternatives to Improve Hyperpigmentation: A Prospective, Randomized, Controlled Split Face Study](https://pubmed.ncbi.nlm.nih.gov/33022197/) Arbutin · Journal of Cosmetic Science, 2020
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- ['All-natural' anti-wrinkle emulsion serum with Acmella oleracea extract: A design of experiments (DoE) formulation approach, rheology and in vivo skin performance/efficacy evaluation](https://pubmed.ncbi.nlm.nih.gov/34297422/) Acmella oleracea extract · International Journal of Cosmetic Science, 2021
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel extract · Journal of Cosmetic Science, 2018
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [New topical tranexamic acid derivative for the improvement of hyperpigmentation and inflammation in the sun-damaged skin](https://pubmed.ncbi.nlm.nih.gov/32588531/) Cetyl tranexamate mesylate · Journal of Cosmetic Dermatology, 2021
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation](https://pubmed.ncbi.nlm.nih.gov/37183632/) Arbutin · Biomaterials Science, 2023
- [Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres](https://pubmed.ncbi.nlm.nih.gov/25876142/) Papain · Giornale Italiano Di Dermatologia E Venereologia, 2015
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Dimethoxytolyl propylresorcinol · Journal of Cosmetic Dermatology, 2021
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Multi-peptides · Journal of Cosmetic Dermatology, 2010
- [Algae extract protection effect on oxidized protein level in human stratum corneum](https://pubmed.ncbi.nlm.nih.gov/15247018/) Algae extract · Annals of the New York Academy of Sciences, 2004
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2022
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 3-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Amended safety assessment of Sesamum indicum (sesame) seed oil, hydrogenated sesame seed oil, Sesamum indicum (sesame) oil unsaponifiables, and sodium sesameseedate](https://pubmed.ncbi.nlm.nih.gov/21772026/) Sesamum indicum oil · International Journal of Toxicology, 2011
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties](https://pubmed.ncbi.nlm.nih.gov/39617635/) Acmella oleracea extract · International Journal of Cosmetic Science, 2025
- [Taurine and Polyphenol Complex Repaired Epidermal Keratinocyte Wounds by Regulating IL8 and TIMP2 Expression](https://pubmed.ncbi.nlm.nih.gov/39194729/) Ilex paraguariensis leaf extract · Current Issues in Molecular Biology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects](https://pubmed.ncbi.nlm.nih.gov/25362595/) Hippophae rhamnoides oil · Pakistan Journal of Pharmaceutical Sciences, 2014
- [Development and efficacy assessments of tea seed oil makeup remover](https://pubmed.ncbi.nlm.nih.gov/27988044/) Camellia oleifera seed oil · Annales Pharmaceutiques Francaises, 2017
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride, Capric triglyceride · Life, 2023
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Effects of a Postbiotic Saccharomyces and Lactobacillus Ferment Complex on the Scalp Microbiome of Chinese Women with Sensitive Scalp Syndrome](https://pubmed.ncbi.nlm.nih.gov/37767337/) Lactobacillus ferment · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Pleiotropic effects of a Camellia sinensis leaf extract on in vitro and in vivo skin health characteristics](https://pubmed.ncbi.nlm.nih.gov/40391588/) Camellia sinensis leaf water · International Journal of Cosmetic Science, 2025
- [Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41319188/) Camellia oleifera seed oil · International Journal of Cosmetic Science, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Saccharomyces ferment filtrate · Skinmed, 2021
- [Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/37194909/) Camellia sinensis leaf water · Journal of Cosmetic Dermatology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter, Shea butter · Lasers in Medical Science, 2025
- [The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/41668671/) Laminaria digitata extract · International Journal of Cosmetic Science, 2026
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- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
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- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026

## The brands

- American skincare: [Good Molecules](https://lovi.care/skincare/ie/brands/good-molecules)
- American skincare: [Clinique](https://lovi.care/skincare/ie/brands/clinique)

## More comparisons

- [SKIN1004 vs Good Molecules](https://lovi.care/skincare/ie/compare/skin1004-vs-good-molecules)
- [SKIN1004 vs Clinique](https://lovi.care/skincare/ie/compare/skin1004-vs-clinique)
- [Anua vs Good Molecules](https://lovi.care/skincare/ie/compare/anua-vs-good-molecules)
- [Anua vs Clinique](https://lovi.care/skincare/ie/compare/anua-vs-clinique)
- [Medicube vs Good Molecules](https://lovi.care/skincare/ie/compare/medicube-vs-good-molecules)
- [Medicube vs Clinique](https://lovi.care/skincare/ie/compare/medicube-vs-clinique)
- [The Ordinary vs Good Molecules](https://lovi.care/skincare/ie/compare/the-ordinary-vs-good-molecules)
- [The Ordinary vs Clinique](https://lovi.care/skincare/ie/compare/the-ordinary-vs-clinique)
- [Beauty of Joseon vs Good Molecules](https://lovi.care/skincare/ie/compare/beauty-of-joseon-vs-good-molecules)
- [Beauty of Joseon vs Clinique](https://lovi.care/skincare/ie/compare/beauty-of-joseon-vs-clinique)
- [COSRX vs Good Molecules](https://lovi.care/skincare/ie/compare/cosrx-vs-good-molecules)
- [COSRX vs Clinique](https://lovi.care/skincare/ie/compare/cosrx-vs-clinique)
- [CeraVe vs Good Molecules](https://lovi.care/skincare/ie/compare/cerave-vs-good-molecules)
- [CeraVe vs Clinique](https://lovi.care/skincare/ie/compare/cerave-vs-clinique)
- [La Roche-Posay vs Good Molecules](https://lovi.care/skincare/ie/compare/la-roche-posay-vs-good-molecules)
- [La Roche-Posay vs Clinique](https://lovi.care/skincare/ie/compare/la-roche-posay-vs-clinique)
- [Dr. Althea vs Good Molecules](https://lovi.care/skincare/ie/compare/dr-althea-vs-good-molecules)
- [Dr. Althea vs Clinique](https://lovi.care/skincare/ie/compare/dr-althea-vs-clinique)
- [Some By Mi vs Good Molecules](https://lovi.care/skincare/ie/compare/some-by-mi-vs-good-molecules)
- [Some By Mi vs Clinique](https://lovi.care/skincare/ie/compare/some-by-mi-vs-clinique)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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