# BIOEFFECT vs Trilogy

Page: https://lovi.care/skincare/ie/compare/bioeffect-vs-trilogy

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

BIOEFFECT and Trilogy are skincare lines offering targeted [serums](https://lovi.care/skincare/ie/ingredients/serum), advanced formulas, thoughtful moisturizers, and gentle cleansers. The first brand suits mature skin best with cherished standout products like the EGF Serum for acne-prone skin, while the second is deeply loved for dry, balanced, and sensitive skin types through items such as the [Vitamin C](https://lovi.care/skincare/ie/ingredients/vitamin-c) Ceramide Night Cream for acne-prone skin, the [Rosehip](https://lovi.care/skincare/ie/ingredients/rosehip-oil) Cream Cleanser for skin with dark spots, and the Line Smoothing Day Cream for mature skin. Both provide refined care for daily routines, differing primarily in their specific ingredients and the optimal skin types they serve.

This page compares some of the most popular BIOEFFECT and Trilogy products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pga754bd71d8).

### Popular BIOEFFECT vs Trilogy products

#### BIOEFFECT

- [EGF Serum](https://lovi.care/skincare/ie/p/bioeffect/egf-serum/for/dry-skin) — Superior fit

#### Trilogy

- [Rosehip Cream Cleanser](https://lovi.care/skincare/ie/p/trilogy/rosehip-cream-cleanser/for/sensitive-skin) — High fit
- [Line Smoothing Day Cream](https://lovi.care/skincare/ie/p/trilogy/line-smoothing-day-cream/for/dry-skin) — High fit
- [Vitamin C Ceramide Night Cream](https://lovi.care/skincare/ie/p/trilogy/vitamin-c-ceramide-night-cream/for/mature-skin) — High fit

## Questions and answers

### BIOEFFECT or Trilogy: which is better?

BIOEFFECT is a better choice for dry, sensitive, or mature skin because EGF [Serum](https://lovi.care/skincare/ie/ingredients/serum) achieves a Superior Lovi fit across all three types, whereas Trilogy's products reach only High or Average fits. Furthermore, every product on the BIOEFFECT page lists no fragrance, while two of Trilogy's three products contain fragrance.

### What is the difference between BIOEFFECT and Trilogy?

BIOEFFECT offers the EGF Serum on this page, which Lovi rates as a Superior fit for dry, dry sensitive, and mature skin, and every product on this page lists no fragrance. Trilogy offers three different products, including cleansers and moisturizers, where Lovi fit levels vary widely from High to Low, and some products include fragrance.

### Which is more affordable, BIOEFFECT or Trilogy?

The provided page and study details do not contain pricing information, so it is not possible to determine whether BIOEFFECT or Trilogy is more affordable.

### Which causes fewer breakouts, BIOEFFECT or Trilogy?

BIOEFFECT has a Superior or High Lovi fit for acne-prone skin with the products on this page, whereas Trilogy ranges from High to Average or Low.

### Which brand offers products with no fragrance, BIOEFFECT or Trilogy?

BIOEFFECT offers products with no fragrance, as every product on this page lists no fragrance in its ingredients, whereas Trilogy features fragrance in two of its three products on this page.

### How do the founding years of BIOEFFECT and Trilogy compare?

BIOEFFECT was founded in 2010, whereas Trilogy was founded earlier in 2002.

### Which Trilogy products are formulated with fragrance?

Among the products on this page, the [Rosehip](https://lovi.care/skincare/ie/ingredients/rosehip-oil) Cream Cleanser and the [Vitamin C](https://lovi.care/skincare/ie/ingredients/vitamin-c) Ceramide Night Cream are formulated with fragrance. The Line Smoothing Day Cream is the only Trilogy product on this page that lists no fragrance in its ingredients.

## Research behind their key ingredients

- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Sodium hyaluronate · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Topical Almond Oil for Prevention of Pressure Injuries: A Single-Blinded Comparison Study](https://pubmed.ncbi.nlm.nih.gov/32379165/) Prunus amygdalus dulcis oil · Journal of Wound, Ostomy, and Continence Nursing, 2020
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Monocentric, Vehicle-Controlled, Double-Blind Study to Assess the Short- and Long-Term Effects of a Ceramide NP C15-Containing Emollient on the Skin Microbiome and the Skin Barrier Function in Sensitive Skin](https://pubmed.ncbi.nlm.nih.gov/41758783/) Ceramide iii · Skin Pharmacology and Physiology, 2026

## The brands

- Skincare: [BIOEFFECT](https://lovi.care/skincare/ie/brands/bioeffect)
- Skincare: [Trilogy](https://lovi.care/skincare/ie/brands/trilogy)

## More comparisons

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- [SKIN1004 vs Trilogy](https://lovi.care/skincare/ie/compare/skin1004-vs-trilogy)
- [Anua vs BIOEFFECT](https://lovi.care/skincare/ie/compare/anua-vs-bioeffect)
- [Anua vs Trilogy](https://lovi.care/skincare/ie/compare/anua-vs-trilogy)
- [Medicube vs BIOEFFECT](https://lovi.care/skincare/ie/compare/medicube-vs-bioeffect)
- [Medicube vs Trilogy](https://lovi.care/skincare/ie/compare/medicube-vs-trilogy)
- [The Ordinary vs BIOEFFECT](https://lovi.care/skincare/ie/compare/the-ordinary-vs-bioeffect)
- [The Ordinary vs Trilogy](https://lovi.care/skincare/ie/compare/the-ordinary-vs-trilogy)
- [Beauty of Joseon vs BIOEFFECT](https://lovi.care/skincare/ie/compare/beauty-of-joseon-vs-bioeffect)
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- [COSRX vs BIOEFFECT](https://lovi.care/skincare/ie/compare/cosrx-vs-bioeffect)
- [COSRX vs Trilogy](https://lovi.care/skincare/ie/compare/cosrx-vs-trilogy)
- [CeraVe vs BIOEFFECT](https://lovi.care/skincare/ie/compare/cerave-vs-bioeffect)
- [CeraVe vs Trilogy](https://lovi.care/skincare/ie/compare/cerave-vs-trilogy)
- [La Roche-Posay vs BIOEFFECT](https://lovi.care/skincare/ie/compare/la-roche-posay-vs-bioeffect)
- [La Roche-Posay vs Trilogy](https://lovi.care/skincare/ie/compare/la-roche-posay-vs-trilogy)
- [Dr. Althea vs BIOEFFECT](https://lovi.care/skincare/ie/compare/dr-althea-vs-bioeffect)
- [Dr. Althea vs Trilogy](https://lovi.care/skincare/ie/compare/dr-althea-vs-trilogy)
- [Some By Mi vs BIOEFFECT](https://lovi.care/skincare/ie/compare/some-by-mi-vs-bioeffect)
- [Some By Mi vs Trilogy](https://lovi.care/skincare/ie/compare/some-by-mi-vs-trilogy)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/bioeffect-vs-trilogy
- United Kingdom: https://lovi.care/skincare/uk/compare/bioeffect-vs-trilogy
- Ireland: https://lovi.care/skincare/ie/compare/bioeffect-vs-trilogy (this page)
- Germany: https://lovi.care/skincare/de/compare/bioeffect-vs-trilogy
- France: https://lovi.care/skincare/fr/compare/bioeffect-vs-trilogy
- Italy: https://lovi.care/skincare/it/compare/bioeffect-vs-trilogy
- Netherlands: https://lovi.care/skincare/nl/compare/bioeffect-vs-trilogy
- Spain: https://lovi.care/skincare/es/compare/bioeffect-vs-trilogy
- Canada: https://lovi.care/skincare/ca/compare/bioeffect-vs-trilogy
- Australia: https://lovi.care/skincare/au/compare/bioeffect-vs-trilogy
- Singapore: https://lovi.care/skincare/sg/compare/bioeffect-vs-trilogy
- Saudi Arabia: https://lovi.care/skincare/sa/compare/bioeffect-vs-trilogy
- United Arab Emirates: https://lovi.care/skincare/ae/compare/bioeffect-vs-trilogy