# Vivant DERM-A-GEL for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Vivant](https://lovi.care/skincare/fr/brands/vivant)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for normal skin, as Retinyl Propionate and Niacinamide provide antioxidant activity and barrier repair, but lacks specialized ingredients to directly target your wrinkles and fine lines.
- The presence of lactic acid offers mild exfoliation and skin renewal, which is generally beneficial for normal skin.
- The product is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/oily-acne-prone-skin): Average

## Key ingredients

Retinyl Propionate, Niacinamide, Kojic Acid, Glycereth-26, Lactic Acid

## What the research says

- Topical retinyl propionate cream produced no statistically significant differences compared to placebo for any clinical, histological, or profilometric parameters of skin photoageing in 80 subjects. ([Clinical and Experimental Dermatology, 1998](https://pubmed.ncbi.nlm.nih.gov/9894360/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A vitamin A palmitate and antioxidant-containing oil-based moisturizer improved fine lines, wrinkles, pigmentation, tone, texture, dryness, firmness, and clarity across various body sites compared to a no-treatment group over 12 weeks. ([Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23438139/))
- Topical Retinol palmitate improves tear production, reduces corneal and conjunctival staining, decreases ocular surface keratinization, and promotes goblet cell development in patients with chronic Stevens-Johnson Syndrome with ocular surface keratinization compared to conventional treatment. ([The Ocular Surface, 2023](https://pubmed.ncbi.nlm.nih.gov/37689180/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A topical formulation containing kojic acid, emblica extract, and glycolic acid demonstrated efficacy parity compared with hydroquinone 4% in multiethnic participants with mild to moderate facial dyschromia. ([Cutis, 2010](https://pubmed.ncbi.nlm.nih.gov/21049734/))
- A nanoemulsion containing 1 mg/mL kojic dipalmitate and 5% rosehip oil demonstrated high incorporation efficiency, suitable physicochemical stability, antioxidant and depigmenting efficacy close to 1 mM ascorbic acid, and no cytotoxicity at concentrations from 0.06% to 1% in vitro. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36839792/))
- Topical application of iron chelators kojic acid and deferiprone significantly accelerated wound healing in rats compared to control groups, with deferiprone showing superior efficacy due to higher antioxidant and iron chelation abilities. ([International Wound Journal, 2013](https://pubmed.ncbi.nlm.nih.gov/22621771/))
- Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin. ([Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15027519/))
- Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties. ([Journal of the American Academy of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1597538/))
- A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33178384/))

## Why other serums fit mature skin better

- Topical application of retinol and retinoic acid both increased epidermal thickness and upregulated collagen genes and proteins in human skin, with retinol producing similar histological and molecular changes to retinoic acid alongside a significant reduction in facial wrinkles after 12 weeks. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

This retinoid serum is highly praised for its ability to significantly improve skin texture, reduce acne, and diminish fine lines, with most users experiencing a clearer complexion quickly. Some users report a mild adjustment period with dryness or purging. The data is based on approximately 175 reviews.

- Liked: Clears acne breakouts (mostly mentioned)
- Liked: Gentle on skin (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Promotes glowing skin (sometimes noted)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Initial skin purging (sometimes noted)
- Disliked: Mild dryness/peeling (sometimes noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Vivant DERM-A-GEL serum work for mature skin?

Vivant DERM-A-GEL works moderately well for mature skin, providing antioxidant support and mild renewal, but it lacks specialized ingredients to directly target wrinkles and fine lines. To give mature skin the best anti-aging results, a product of this type needs high-quality ingredients that target fine lines, alongside potent antioxidants, nourishing oils, and peptides.
Sources: [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/), [The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/)

### Which ingredients make this serum a good fit for mature skin?

Retinyl propionate, niacinamide, and lactic acid make this serum a good fit for mature skin by providing antioxidant activity, barrier repair, and mild exfoliation that help renew the skin. However, mature skin needs specialized anti-aging ingredients that directly target wrinkles and fine lines.
Sources: [The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/), [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/)

### What does Retinyl Propionate do for mature skin?

Retinyl propionate helps smooth the look of wrinkles and deep lines while improving skin firmness and dark spots on mature skin. It works to reduce signs of aging with a low likelihood of irritation, making it much more comfortable for daily use than stronger prescription options.
Sources: [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/), [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/28733999/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, as putting treatments in the PM provides simplicity and extra safety around sun exposure. Mature skin needs products featuring targeted ingredients for wrinkles and fine lines, alongside antioxidants and barrier repair agents.

### Can I use this serum with glycolic acid, and in what order?

It is best to avoid using this treatment and glycolic acid in the same routine, as combining them may cause dryness or irritation on mature skin. Instead, alternate them on different nights or use glycolic acid in your morning routine and this product at night.

### How often should I use this serum?

Use this treatment once a week in the evening to let your skin adjust safely, and you may slowly use it more often if your skin tolerates it well. This type of product works best for mature skin when it includes specialized ingredients that directly smooth fine lines and wrinkles.

### Can this serum clog pores, cause breakouts or purging for mature skin?

Yes, this treatment may cause initial skin purging and mild breakouts when you first start using it. To best care for mature skin, a product of this type needs smoothing ingredients and antioxidants that deeply target wrinkles and fine lines.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/fr/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/fr/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €139.99 at Amazon
- [La Prairie Skin Caviar Liquid Lift](https://lovi.care/skincare/fr/p/la-prairie/skin-caviar-liquid-lift/for/mature-skin) — High fit — €599.90 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/mature-skin) — Superior fit — €28.02 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €18.45 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/fr/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €76.29 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycereth-26, Sorbitan Sesquioleate, Retinyl Propionate, Ethylhexyl Dimethyl Paba, Carbomer, Kojic Acid, Bht, Propylene Glycol, Sodium Lactate, Sodium Pca, Glycine, Fructose, Urea, Niacinamide, Inositol, Sodium Benzoate, Lactic Acid, Disodium Edta, Polysorbate 80, Sodium Hydroxide, Ethylhexylglycerin, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/vivant/derm-a-gel/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/vivant/derm-a-gel/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/vivant/derm-a-gel/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/vivant/derm-a-gel/for/mature-skin
- France: https://lovi.care/skincare/fr/p/vivant/derm-a-gel/for/mature-skin (this page)
- Italy: https://lovi.care/skincare/it/p/vivant/derm-a-gel/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/vivant/derm-a-gel/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/vivant/derm-a-gel/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/vivant/derm-a-gel/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/vivant/derm-a-gel/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/vivant/derm-a-gel/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/vivant/derm-a-gel/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/vivant/derm-a-gel/for/mature-skin