# Timeless Matrixyl 3000 Serum for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Timeless](https://lovi.care/skincare/fr/brands/timeless)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- Offers excellent wrinkle reduction for you, as Matrixyl 3000 and Sodium Hyaluronate work to plump and minimize fine lines, while Glycerin and Sodium Hyaluronate provide essential hydration for your dry skin.
- The formula is highly suitable for dry skin due to the humectant action of Glycerin and Sodium Hyaluronate, which effectively draw water into the skin.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Matrixyl 3000, Sodium Hyaluronate, Glycerin, Aloe Barbadensis, Dehydroacetic Acid

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Microbial cellulose patches containing 1,3-dihydroxy-2-propanone act as biocarriers that enable DHA transport into the stratum corneum and induce skin color changes, with intensity increasing with concentration and application time. ([Polymers, 2018](https://pubmed.ncbi.nlm.nih.gov/30966473/))
- Topical treatment with docosahexaenoic acid (DHA) upregulated barrier differentiation proteins and reduced inflammatory cytokine expression in human keratinocytes and inflammatory reconstructed human epidermis models. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31480216/))

## What reviewers say

Based on a very large amount of data, this serum is highly praised for its ability to deeply hydrate, plump, and soften the skin, making it a favorite for mature and dry skin types targeting fine lines and loss of elasticity. The vast majority of users appreciate its lightweight, non-sticky texture and noticeable firming outcomes. A small subset of reviewers report a lack of visible anti-aging results or express disappointment with the price-to-value ratio.

- Liked: Hydrating, plumping (mostly mentioned)
- Liked: Lightweight, absorbs fast (mostly mentioned)
- Liked: Improves firmness (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Old product (rarely noted)
- Disliked: Poor value (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Timeless Matrixyl 3000 Serum a great fit for dry skin?

Timeless Matrixyl 3000 Serum is a great fit because Glycerin and Sodium Hyaluronate draw in water to give your dry skin essential hydration, while Matrixyl 3000 helps plump and minimize fine lines. It is also very safe and unlikely to cause irritation because it leaves out harsh ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry skin?

Glycerin and sodium hyaluronate make this serum a great fit for dry skin by drawing in water to keep it soft and hydrated. Matrixyl 3000 also helps smooth out fine lines and wrinkles.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Matrixyl 3000 do for dry skin?

Matrixyl 3000 helps smooth fine lines and supports collagen levels to keep dry skin looking firm and youthful. Using peptide combinations like this may improve overall skin texture and strength over time.
Sources: [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/)

### What does Hyaluronic Acid do for dry skin?

Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### Where does this serum go in a skincare routine for dry skin?

This treatment serum goes in your evening routine after cleansing and before moisturizing, which keeps things simple and safe around sun exposure. It is unlikely to irritate dry skin because the formula lacks harsh or prohibited ingredients.

### Can I use this serum with vitamin C, and in what order?

You can use this serum with vitamin C by applying vitamin C first in your morning routine and this treatment at night, or by layering them with vitamin C first followed by this serum. Using these ingredients together is unlikely to irritate dry skin because the formula has a very safe profile without harsh ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

This serum is used in the evening as part of your routine. It is unlikely to cause irritation for your dry skin, and it helps smooth fine lines while bringing essential moisture to your face.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is a great fit for dry skin and is unlikely to clog pores, cause breakouts, or lead to purging. Its gentle formula relies on hydrating ingredients that draw water into the skin without using harsh additives.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €18.25 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/fr/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — €57.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/fr/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €29.58 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/fr/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €7.50 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — €18.55 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/fr/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-skin) — Superior fit — €76.29 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Matrixyl 3000, Aloe Barbadensis, Glycerin, Sodium Hyaluronate, Benzyl Alcohol, Dehydroacetic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/timeless/matrixyl-3000-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/timeless/matrixyl-3000-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/timeless/matrixyl-3000-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/timeless/matrixyl-3000-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/timeless/matrixyl-3000-serum/for/dry-skin (this page)
- Italy: https://lovi.care/skincare/it/p/timeless/matrixyl-3000-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/timeless/matrixyl-3000-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/timeless/matrixyl-3000-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/timeless/matrixyl-3000-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/timeless/matrixyl-3000-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/timeless/matrixyl-3000-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/timeless/matrixyl-3000-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/timeless/matrixyl-3000-serum/for/dry-skin