# The History of Whoo Bichup Self-Generating Anti-Aging Concentrate for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: The History of Whoo
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate anti-aging benefits for your combination skin, as oligopeptides and acetyl hexapeptide-8 work to minimize fine lines and wrinkles.
- Glycerin and panthenol provide general hydration and soothing effects, which are beneficial for your oily shine, though not specifically targeted for oil control.
- The product is safe for your combination skin with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Ceramide Np, Panax Ginseng Root Extract, Copper Tripeptide-1, Hydrolyzed Soy Protein

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects. ([Rejuvenation Research, 2015](https://pubmed.ncbi.nlm.nih.gov/25867599/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline. ([Journal of Toxicology and Environmental Health. Part A, 2020](https://pubmed.ncbi.nlm.nih.gov/32564709/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Many users report plumper, firmer skin with diminished fine lines. However, some find the texture sticky and the floral fragrance overpowering.

- Liked: Deep hydration (often mentioned)
- Liked: Radiant glow (often mentioned)
- Disliked: Strong fragrance (often mentioned)
- Liked: Plumping effect (sometimes noted)
- Liked: Soothing & healing (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Awkward packaging (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Whoo Bichup Self-Generating Anti-Aging Concentrate work for combination skin?

This treatment is an average fit for combination skin, offering moderate anti-aging benefits and hydration through peptides and glycerin, though other options manage oily shine better. To work best for this skin type, a treatment needs ingredients like niacinamide and propolis or zinc PCA that regulate oiliness and enhance radiance while keeping hydration balanced.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### Which ingredients make this serum a good fit for combination skin?

Glycerin and panthenol help provide soothing hydration, while oligopeptides and acetyl hexapeptide-8 work to minimize fine lines and wrinkles. To be a better fit for combination skin, this type of product needs ingredients like niacinamide and zinc PCA to help regulate oiliness and manage oily shine.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What do Ceramides do for combination skin?

Ceramides help balance combination skin by supporting the skin barrier in dry areas without feeling heavy on oily zones, keeping the skin smooth and comfortable. They play an essential role in maintaining the outer water barrier, and a moisturizer with ceramides and light hydrators works well for this skin type.
Sources: [American Journal of Clinical Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12553851/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in your evening routine after cleansing and before moisturizing, though some treatments may also be used in the morning or twice a day. For combination skin, a product of this type needs balancing ingredients like niacinamide, light hydrators such as glycerin, and oil-controlling elements to properly manage both dry and oily areas.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying the retinol first, letting it absorb, and then following with this concentrate. This product works well for combination skin, though this skin type also benefits from targeted oil-control ingredients.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine, or even twice a day if your skin tolerates it well. Combination skin works best with a treatment that balances hydration without heavy oils and includes lightweight soothing ingredients.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### Can it clog pores, cause breakouts or purging for combination skin?

This concentrate is unlikely to clog pores or cause breakouts on combination skin, as it has a safe formula without harsh irritants. However, because it contains rich oils and butter that provide deep moisture, a product for this skin type typically needs lightweight hydrators and oil-balancing ingredients to keep the oily zones clear.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl salicylate, citronellol, geraniol, limonene, and linalool).

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — €18.25 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/fr/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €35.99 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/fr/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €389.34 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice RESIST Perfectly Balanced Foaming Cleanser](https://lovi.care/skincare/fr/p/paula-s-choice/perfectly-balanced-foaming-cleanser/for/combination-skin) — Superior fit — €32.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/fr/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/fr/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — €17.47 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Dipropylene Glycol, Peg Ppg Polybutylene Glycol-8 5 3 Glycerin, Glyceryl Polymethacrylate, Biosaccharide Gum-1, Dimethicone, 1,2-Hexanediol, Peg-150, Propylene Glycol, Phenyl Trimethicone, Panthenol, Methyl Trimethicone, Cordyceps Sinensis Extract, Nelumbo Nucifera Extract, Nuphar Japonicum Root Extract, Panax Ginseng Root Extract, Ophiopogon Japonicus Root Extract, Rehmannia Chinensis Root Extract, Poria Cocos Extract, Dioscorea Japonica Root Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Typha Angustifolia Spike Extract, Paeonia Albiflora Extract, Scutellaria Baicalensis Root Extract, Angelica Gigas Extract, Saposhnikovia Divaricata Root Extract, Atractylodes Japonica Root Extract, Cinnamomum Cassia Bark Extract, Zingiber Officinale Root Extract, Ziziphus Jujuba Fruit Extract, Angelica Acutiloba Root Extract, Cornus Officinalis Fruit Extract, Velvet Extract, Theobroma Cacao Extract, Thymus Vulgaris Extract, Hydroxyproline, Ceramide Np, Cholesterol, Arbutin, Oligopeptide-1, Oligopeptide-2, Oligopeptide-4, Hydrolyzed Soy Protein, Acetyl Hexapeptide-8, Copper Tripeptide-1, Arginine, Cystine, Histidine Hcl, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan, Tyrosine, Valine, Biotin, Folic Acid, Inositol, Niacinamide, Calcium Pantothenate, Pyridoxine Hcl, Riboflavin, Thiamine Hcl, Cyanocobalamin, Glycosphingolipids, Beta-Glucan, Hydrogenated Lecithin, Peg-10 Rapeseed Sterol, Glyceryl Stearate, Glycereth-20, C14-22 Alcohols, Phytosqualane, Macadamia Ternifolia Seed Oil, Triethylhexanoin, Arachidyl Glucoside, Butyrospermum Parkii Butter Shea Butter, Stearic Acid, Peg-100 Stearate, Polymethylsilsesquioxane, Cyclopentasiloxane, Dimethiconol, Butylene Glycol, Peg-60 Hydrogenated Castor Oil, Carbomer, Algin, Sodium Polyacrylate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sunset Yellow Fcf, Tartrazine, Tromethamine, Trisodium Edta, Alpha-Isomethyl Ionone, Benzyl Salicylate, Citronellol, Geraniol, Hydroxycitronellal, Limonene, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin
- France: https://lovi.care/skincare/fr/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin (this page)
- Italy: https://lovi.care/skincare/it/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin
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