# Sunday Riley A+ High-Dose Retinoid Serum for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Sunday Riley](https://lovi.care/skincare/fr/brands/sunday-riley)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your combination skin, as hydroxypinacolone retinoate and retinol provide retinoid advantages for skin renewal, though it lacks sufficient ingredients for optimal oil control on your oilier areas.
- The inclusion of bisabolol and honey extract offers soothing properties, which is supportive for your skin's general needs.
- The formula is safe for your acne-prone skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/oily-acne-prone-skin): High

## Key ingredients

Retinoid Blend, Ubiquinone, Honey Extract, Hydroxypinacolone Retinoate, Sodium Hyaluronate Crosspolymer

## What the research says

- Hydroxypinacolone retinoate and retinyl propionate at a 5:9 weight ratio synergistically enhanced antiaging gene expressions in vitro and improved skin wrinkles, smoothness, transepidermal water loss, and elasticity in 42 Chinese urban women over an 8-week period without adverse reactions compared to retinol. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36762391/))
- Combined probiotic supplementation and topical azelaic acid with hydroxypinacolone retinoate reduced non-inflammatory lesions from 11.5 to 7.3 and decreased microscopic acne features measured by reflectance confocal microscopy and dynamic optical coherence tomography in 20 patients over 12 weeks. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37510902/))
- Topical retinoids improve global assessment scores and reduce lesion counts compared to vehicle in patients with acne vulgaris, with adapalene demonstrating a superior tolerability profile and benzoyl peroxide combination optimizing results. ([American Journal of Clinical Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30674002/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Trifarotene cream 0.005% resulted in a significantly greater reduction in total atrophic acne scar count compared with vehicle at Week 24 (55.2% vs 29.9%) in patients with atrophic acne scarring. ([Dermatology and Therapy, 2025](https://pubmed.ncbi.nlm.nih.gov/39984798/))
- Topical application of CoQ10 improves mitochondrial function in aging skin in vivo, combating cellular signs of aging caused by an age-dependent shift to a functionally anaerobic energy metabolism. ([BioFactors, 2008](https://pubmed.ncbi.nlm.nih.gov/19096122/))
- Encapsulating coenzyme Q10 in lipid nanoparticles for topical use improves skin compatibility, protects against degradation, increases skin penetration, and provides controlled release to counteract aging effects. ([Colloids and Surfaces. B, Biointerfaces, 2023](https://pubmed.ncbi.nlm.nih.gov/37574615/))
- Review of topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles highlights their improved bioavailability, chemical stability, skin absorption, and photoprotective effects. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34206935/))
- Honey-based dressings reduced mean healing duration, length of hospital stay, and VAS pain scores compared with povidone iodine-based dressings in 1236 participants. ([Journal of Wound Care, 2021](https://pubmed.ncbi.nlm.nih.gov/33856925/))
- Topical honey application improved the mean duration of attacks and pain, occurrence of crusting, and healing time compared to acyclovir cream in 16 adult patients with recurrent labial and genital herpes lesions. ([Medical Science Monitor, 2004](https://pubmed.ncbi.nlm.nih.gov/15278008/))
- A topical serum containing hydroxypinacolone retinoate and peptides used twice daily for 16 weeks achieved parity or statistically significantly better improvement in facial aging parameters compared to a single fractional CO2 laser treatment in women with moderate global photodamage. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39394831/))
- A new topical gel formulation reduced total acne lesions by 80% and GAGS scores by 78% after 8 weeks in 22 female patients with mild facial acne without impairing skin barrier function or causing side effects. ([Giornale Italiano Di Dermatologia E Venereologia, 2020](https://pubmed.ncbi.nlm.nih.gov/32869963/))
- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other serums fit acne-prone skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))

## What reviewers say

Users frequently praise this serum for its ability to deliver retinoid benefits like smoothed texture and reduced fine lines with minimal irritation, making it suitable for sensitive skin or retinoid beginners. The formula includes soothing botanicals that help mitigate dryness and redness, improving overall skin clarity and radiance.

- Liked: Gentle, non-irritating (mostly mentioned)
- Liked: Smoother texture (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Anti-aging results (sometimes noted)
- Liked: Moisturizing formula (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Initial breakouts (rarely noted)
- Disliked: Strength claims (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Sunday Riley A+ Retinoid Serum work for acne-prone skin?

Sunday Riley A+ High-Dose Retinoid Serum works moderately well for your acne-prone skin, providing skin renewal benefits and soothing properties while remaining safe against irritation. However, it lacks sufficient ingredients for optimal oil control on oilier areas. A product of this type needs effective ingredients like niacinamide, zinc PCA, and propolis to control oil and breakouts while keeping combination skin balanced.
Sources: [Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37510902/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is an average fit for acne-prone skin because hydroxypinacolone retinoate and retinol help with skin renewal, while bisabolol and honey extract calm the skin. To work best for this skin type, a product of this type needs ingredients like niacinamide, propolis, and zinc PCA to control oil while providing balanced hydration.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36762391/)

### What does Retinoid do for acne-prone skin?

Retinoids serve as the core treatment for acne-prone skin because they help clear clogged pores, reduce inflammation, and calm breakouts. They significantly modulate genes involved in skin healing and cell turnover, though they may cause temporary irritation.
Sources: [Journal of Drugs in Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35816067/), [Dermatology and Therapy, 2017](https://pubmed.ncbi.nlm.nih.gov/28585191/)

### What does Coenzyme Q10 do for acne-prone skin?

Coenzyme Q10 helps protect acne-prone skin by reducing free radicals and boosting antioxidant levels. It is unlikely to cause irritation and may support overall skin health when used as part of your routine.
Sources: [BioFactors, 2015](https://pubmed.ncbi.nlm.nih.gov/26648450/), [The Journal of Clinical and Aesthetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39148958/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine as a treatment step, applied after cleansing and before moisturizing. Putting active treatments at night helps keep skin safe from extra sun exposure while it works.

### Can I use it with vitamin C, and in what order?

You can use this treatment alongside vitamin C by applying your vitamin C in the morning and this serum at night. This routine lets you get the smoothing benefits of both without overwhelming your skin. Acne-prone skin of this type also needs dedicated ingredients for oil control to keep oilier areas balanced.

### How often should I use this serum?

Use this serum in your evening routine, starting slowly to see how your skin adjusts. Acne-prone skin needs a product that also provides oil control to work best for it.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36762391/)

### Can it clog pores, cause breakouts or purging for acne-prone skin?

This serum may cause initial breakouts for acne-prone skin, though the formula is generally safe and unlikely to cause severe irritation due to soothing ingredients like bisabolol and honey extract. To better fit acne-prone skin, a product of this type needs additional oil-controlling ingredients to manage oilier areas effectively.
Sources: [Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37510902/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €18.25 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/fr/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/fr/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €139.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/fr/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.98 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/fr/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €10.25 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/fr/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €17.90 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water Eau Agua, Propanediol, Dimethyl Isosorbide, Triheptanoin, Dimethicone, Glycerin, Pentylene Glycol, Hexyldecanol, Disiloxane, Cetyl Peg Ppg-10 1 Dimethicone, Diheptyl Succinate, Propylene Carbonate, Hydroxypinacolone Retinoate, Ppg-24-Glycereth-24, Phenyl Trimethicone, Retinol, Ubiquinone, Honey Extract, Sodium Hyaluronate Crosspolymer, Algae Extract, Zingiber Officinale Extract, Opuntia Ficus-Indica Fruit Extract, Bisabolol, Butyrospermum Parkii Butter Shea Butter, Yeast Extract, Lecithin, Sodium Acrylates Copolymer, Hydrogenated Polyisobutene, 1,2-Hexanediol, 4-T-Butylcyclohexanol, Polyglyceryl-10 Stearate, Caprylyl Glycol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Sorbitol, Cetylhydroxyproline Palmitamide, Polysilicone-11, Benzoic Acid, Dehydroacetic Acid, Sodium Phytate, Glyceryl Polyacrylate, Polysorbate, Hydroxyphenyl Propamidobenzoic Acid, Stearic Acid, Brassica Campestris Sterols, Pvp, Capryloyl Glycerin Sebacic Acid Copolymer, Sodium Benzoate, Alcohol, Potassium Phosphate, Decyl Glucoside, Phenoxyethanol, Hexylene Glycol, Potassium Sorbate, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin (this page)
- Italy: https://lovi.care/skincare/it/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin