# SkinMedica HA5 Rejuvenating Hydrator for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [SkinMedica](https://lovi.care/skincare/fr/brands/skinmedica)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for mature skin.

## Why this fit

- Highly suitable for your normal skin, this product delivers excellent hydration through multiple forms of hyaluronic acid, such as sodium hyaluronate crosspolymer and hydrolyzed hyaluronic acid, which support skin moisture. While beneficial for general hydration, the formula does not specifically target your concerns with wrinkles and fine lines.
- The inclusion of glycerin further enhances humectant action, reinforcing the product's ability to maintain skin hydration.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of harsh ingredients and the presence of soothing components like whey protein.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Glycerin, Dimethicone, Vitis Vinifera Flower Cell Extract Grape Flower Cell Extract, Trehalose

## What the research says

- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Polyelectrolyte nanocomplexes of quaternized cyclodextrin grafted chitosan and low molecular weight hyaluronic acid improved skin texture and elasticity by increasing skin hydration in clinical evaluation. ([Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Topical treatment with Thealoz Duo significantly improved dry eye disease symptoms, tear break-up time, and restored tear lipid layer functionality by reducing inflammatory response proteins in moderate to severe dry eye patients over 56 days. ([Journal of Clinical Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/40807147/))

## What reviewers say

Based on a very large amount of data, users consistently praise this hydrator for its ability to deliver immediate, deep moisture that plumps the skin and smooths fine lines, often describing it as a "drink of water" for dry or aging complexions. The silicone-heavy formula provides a silky, primer-like finish that improves texture. Some users find the price point high and the application technique necessary to avoid product pilling.

- Liked: Intense hydration (mostly mentioned)
- Liked: Lightweight feel (often mentioned)
- Liked: Silky texture (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Chemical scent (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Risk of counterfeits (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes SkinMedica HA5 Rejuvenating Hydrator a great fit for mature skin?

SkinMedica HA5 Rejuvenating Hydrator is a great fit for mature skin because it delivers rich hydration through multiple forms of hyaluronic acid and glycerin, which help keep the skin feeling soft and smooth. It has an excellent safety profile with soothing ingredients and no harsh components, making it very unlikely to cause irritation.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this treatment a good fit for mature skin?

Sodium hyaluronate and glycerin make this treatment a great fit by delivering deep moisture to help keep skin plump and smooth. Trehalose and various plant extracts further support hydration, while dimethicone helps lock it all in for a soft feel.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### What does Glycerin do for mature skin?

Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this treatment go in a skincare routine for mature skin?

This treatment goes in the evening routine for mature skin, applied after cleansing and toning and before moisturizing. Putting treatments in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this treatment with retinol, and in what order?

Yes, you can use this treatment with retinol by applying the treatment first and then the retinol, or as directed by your routine. Using a moisturizing treatment like this helps keep mature skin comfortable and hydrated while you use active ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this treatment?

This moisturizing treatment is well suited for daily use to keep your skin hydrated and smooth. Applying it twice a day helps maintain moisture levels and supports overall skin health with a very low risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this treatment clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores or cause breakouts for mature skin due to its very safe formula and soothing ingredients. It helps keep skin soft while being gentle.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this treatment around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because its gentle formula has very good skin tolerance and delivers rich moisture to thin skin. It helps keep these delicate areas soft and smooth without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/fr/p/revision-skincare/hydrating-serum/for/mature-skin) — High fit — €191.05 at Amazon
- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/fr/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/mature-skin) — High fit — €29.00 at Amazon
- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/fr/p/isntree/green-tea-fresh-serum/for/mature-skin) — High fit — €12.56 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/mature-skin) — Superior fit — €28.02 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €18.45 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/fr/p/torriden/dive-in-mild-sunscreen/for/mature-skin) — Superior fit — €24.00 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Dimethicone, Hdi Trimethylol Hexyllactone Crosspolymer, Glycerin, Butylene Glycol, Bis-Peg-8 Dimethicone, Polysilicone-11, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Vitis Vinifera Flower Cell Extract Grape Flower Cell Extract, Vibrio Alginolyticus Ferment Filtrate, Alteromonas Extract Ferment, Porphyridium Cruentum Extract, Whey Protein, Plankton Extract, Trehalose, Urea, Serine, Algin, Caprylyl Glycol, Pullulan, Disodium Phosphate, Potassium Phosphate, Pentylene Glycol, Polymethylsilsesquioxane, Glyceryl Polyacrylate, Sodium Citrate, Sea Water, Sucrose Palmitate, Tocopheryl Acetate, Hydroxyacetophenone, Polysorbate 60, Propanediol, Potassium Sorbate, Citric Acid, Isohexadecane, Polysorbate 80, Silica, Decyl Glucoside, Tromethamine, Ethylhexylglycerin, Phenoxyethanol, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- France: https://lovi.care/skincare/fr/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin (this page)
- Italy: https://lovi.care/skincare/it/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin