# SKIN1004 Madagascar Centella Spot Cream for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [SKIN1004](https://lovi.care/skincare/fr/brands/skin1004)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Offers excellent treatment for acne-prone skin due to Centella Asiatica Extract, Asiaticoside, Madecassic Acid, and Asiatic Acid, which reduce acne lesions and blemishes, while also providing moderate benefits for wrinkles and fine lines by supporting skin repair and collagen production.
- This formulation is suitable for normal skin, as Centella Asiatica Extract and Niacinamide offer anti-inflammatory action and barrier repair.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/combination-skin): Superior
- [Sensitive skin](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/oily-acne-prone-skin): Superior

## Key ingredients

Centella Asiatica Extract, Niacinamide, Madecassic Acid, Asiatic Acid, Panthenol

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Asiatic acid-loaded solid lipid microparticles stabilized with poloxamer-188 reduced porphyrin intensity, enhanced skin barriers, and improved skin hydration and brightness in fifteen participants with mild-to-moderate acne. ([International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The novel high-payload nanosuspension system of Centella asiatica extract increased skin accumulation of asiatic acid, madecassic acid, and asiaticoside by 5-, 4-, and 4.5-fold respectively compared to a marketed cream in porcine skin, with no local skin irritation in normal rats. ([International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34764648/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))

## What reviewers say

Based on limited data, users find this product to be a lightweight gel that effectively calms inflammation and speeds up acne healing without causing dryness. Many users report reduced redness and flattened bumps overnight. However, a moderate number of users found it to be not potent enough for their breakouts, with some experiencing irritation.

- Liked: Light gel texture (mostly mentioned)
- Liked: Soothes acne (often mentioned)
- Liked: Non-drying formula (sometimes noted)
- Disliked: Not potent enough (sometimes noted)
- Liked: Precise packaging (rarely noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: Small quantity (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SKIN1004 Spot Cream a great fit for mature skin?

This cream is a great fit for mature skin because it provides moderate benefits for wrinkles and fine lines by supporting skin repair and collagen production. Its ingredients like Centella Asiatica extract and Niacinamide also help calm the skin and keep it smooth.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for mature skin?

Centella Asiatica Extract, Niacinamide, Madecassic Acid, Asiatic Acid, and Panthenol make this cream a great fit for mature skin by supporting skin repair, improving hydration, and helping smooth out fine lines and wrinkles. Its gentle formulation also calms the skin and strengthens your barrier with little risk of irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/)

### What does Centella Asiatica Extract do for mature skin?

Centella Asiatica Extract helps mature skin by improving moisture, reducing moisture loss, and supporting collagen production to keep skin firm and smooth. It also provides antioxidant and calming benefits that help protect against everyday stress and visible signs of aging.
Sources: [Scientific Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34188145/), [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516082/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this cream go in a skincare routine for mature skin?

This treatment goes in your evening routine, applied before your moisturizer for simplicity and extra safety around sun exposure. It is a great fit for mature skin because it helps calm blemishes and provides moderate benefits for wrinkles and fine lines by supporting skin repair.

### Can I use this cream with retinol, and in what order?

You can use this treatment cream alongside retinol by applying the retinol first, letting it absorb, and then following with this cream to help calm and support your skin. This combination is unlikely to cause irritation because the product has a very safe formula with soothing ingredients like Centella Asiatica Extract and Niacinamide.

### How often should I use this cream?

This treatment is a great fit for your mature skin and is best applied in the evening. It helps reduce blemishes while supporting skin repair and collagen production for fine lines with an excellent safety profile.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to clog pores or cause breakouts for mature skin, as it has a very safe formula with no harsh or prohibited ingredients that could upset your skin. It also features Centella Asiatica Extract and Niacinamide, which help calm the skin and keep pores clear.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/fr/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/fr/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €139.99 at Amazon
- [La Prairie Skin Caviar Liquid Lift](https://lovi.care/skincare/fr/p/la-prairie/skin-caviar-liquid-lift/for/mature-skin) — High fit — €599.90 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/mature-skin) — Superior fit — €28.02 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €18.45 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/fr/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €76.29 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Centella Asiatica Extract, Water, Butylene Glycol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Niacinamide, Caprylic Capric Triglyceride, Polyglyceryl-3 Distearate, Neopentyl Glycol Diheptanoate, Coco-Caprylate Caprate, Panthenol, Polyglycerin-3, Glyceryl Stearate, Carbomer, Tromethamine, Asiaticoside, Madecassic Acid, Asiatic Acid, Glyceryl Stearate Citrate, Ammonium Acryloyldimethyltaurate Vp Copolymer, Glyceryl Acrylate Acrylic Acid Copolymer, Ethylhexylglycerin, Disodium Edta, Gluconolactone
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- France: https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-spot-cream/for/mature-skin (this page)
- Italy: https://lovi.care/skincare/it/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-spot-cream/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-spot-cream/for/mature-skin