# REJURAN Rejuran® Healer Turnover Ampoule for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [REJURAN](https://lovi.care/skincare/fr/brands/rejuran)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate brightening and tone evening for your combination skin, as arbutin and niacinamide help regulate melanogenesis and seboregulation respectively. Aloe barbadensis leaf juice and calendula officinalis flower extract provide supportive hydration and soothing benefits, though they are not primary treatments for your acne concerns.
- The formulation is generally safe for your combination skin, with bisabolol and calendula officinalis flower extract offering soothing properties and no harsh ingredients present.
- This product provides general skincare benefits that are mostly supportive and irrelevant for your specific acne, blemishes, and breakout concerns.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

C-Pdrn

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))

## Why other serums fit acne-prone skin better

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Users frequently report achieving a radiant "glass skin" appearance and deep hydration with this ampoule, noting significant improvements in skin texture and plumpness. It is often praised for its effectiveness in repairing damaged skin barriers, soothing redness, and aiding in the healing of acne scars. A small number of users with oily skin have found it to be slightly heavy for daytime application.

- Liked: Hydration and glow (mostly mentioned)
- Liked: Absorbs quickly (often mentioned)
- Liked: Smoother texture (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Calms redness (sometimes noted)
- Disliked: Awkward packaging (sometimes noted)
- Disliked: Minor breakouts (rarely noted)
- Disliked: Slightly sticky (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Rejuran Healer Turnover Ampoule work for acne-prone skin?

This treatment works moderately well for acne-prone skin by offering some soothing and brightening benefits, but it does not directly target your breakouts. Acne-prone skin needs products containing niacinamide, propolis, or zinc PCA that provide excellent benefits for blemishes and control oiliness while keeping the skin balanced and calm.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/)

### Which ingredients make this serum a good fit for acne-prone skin?

Niacinamide and arbutin help even out skin tone, while aloe juice and calendula extract calm the skin, though this serum lacks targeted blemish treatments. Acne-prone skin needs a treatment with ingredients like niacinamide and propolis or zinc PCA that control oil and soothe breakouts without causing irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does C-Pdrn do for acne-prone skin?

C-PDRN helps calm irritated skin and supports skin healing, making it a useful addition for skin prone to breakouts. It may assist in repairing the skin barrier and improving overall texture when used consistently in your routine.
Sources: [Pharmaceutics, 2025](https://pubmed.ncbi.nlm.nih.gov/40871045/), [Current Pharmaceutical Biotechnology, 2026](https://pubmed.ncbi.nlm.nih.gov/39995124/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment goes in your evening routine, applied after cleansing and before your moisturizer. A product of this type for acne-prone skin needs targeted ingredients like acne-fighting acids or retinoids to properly address breakouts and blemishes.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the treatment first and following with your retinol. Because this product works as an average fit for your acne-prone skin, an acne product of this type needs targeted ingredients that actively clear breakouts and reduce blemishes.

### How often should I use this serum?

Apply this serum in your evening routine, using it once a day or a few times a week. This product needs to target breakouts and blemishes more directly with dedicated ingredients like salicylic acid or benzoyl peroxide to truly help acne-prone skin.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This treatment is generally safe for your skin, though minor breakouts are unlikely to happen. Acne-prone skin needs targeted blemish-fighting ingredients and oil-balancing agents rather than general soothing and brightening care.
Sources: [Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €18.25 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/fr/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/fr/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €139.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/fr/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.98 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/fr/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €10.25 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/fr/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €17.90 at Amazon

## Where to buy

- Amazon.fr: €57.80 (https://www.amazon.fr/dp/B08BZCY3Y1?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Callus Culture Extract Licorice Callus Culture Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract Morus Alba Fruit Extract, Arbutin, Butylene Glycol, Glycerin, Polysorbate 20, Hydrolyzed Dna, Hyaluronic Acid, Carbomer, Xanthan Gum, Adenosine, Tocopheryl Acetate, Niacinamide, Bisabolol, Peg-6, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Benzyl Alcohol, 12-Hexanediol, Dipropylene Glycol, Sodium Chloride, Trehalose, Urea
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin (this page)
- Italy: https://lovi.care/skincare/it/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin