# PCA SKIN ExLinea Pro Peptide Serum for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: Superior · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [PCA SKIN](https://lovi.care/skincare/fr/brands/pca-skin)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Excellent suitability for your combination skin is provided by humectants like Glycerin and Betaine, alongside peptides such as Acetyl Octapeptide-3 and Acetyl Hexapeptide-8 that support skin structure and reduce fine lines.
- While the serum offers excellent wrinkle reduction and hydration, it lacks specialized ingredients to address your oily shine concerns.
- The formulation is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Acetyl Octapeptide-3, Acetyl Hexapeptide-8, Sodium Hyaluronate, Hydrolyzed Wheat Protein, Glycerin

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine. ([Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model. ([International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Application of a cosmetic multiple emulsion containing vitamin C and wheat protein as well as a base formulation increased skin moisture in 11 human volunteers over four weeks, while producing no significant variations in skin sebum, pH, elasticity, melanin, or erythema. ([Pakistan Journal of Pharmaceutical Sciences, 2008](https://pubmed.ncbi.nlm.nih.gov/18166519/))
- The addition of polymers and hydrolysed proteins to model body wash cosmetics improves foaming properties, storage stability, and safety by reducing skin irritant potential, with the polyvinylpyrrolidone/hydrolysed wheat protein crosspolymer showing the strongest reduction effect. ([Colloids and Surfaces. B, Biointerfaces, 2015](https://pubmed.ncbi.nlm.nih.gov/26291586/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

This serum is highly praised for its effectiveness in reducing expression lines around the eyes, forehead, and mouth, with many users experiencing a noticeable smoothing or tightening effect. It is particularly favored by those with mature skin for enhancing texture and firmness. Some users, however, find the price to be high in relation to the results they observed.

- Liked: Reduces fine lines (often mentioned)
- Liked: Improves texture (sometimes noted)
- Liked: Lifts and firms (sometimes noted)
- Disliked: High price point (sometimes noted)
- Liked: Absorbs quickly (rarely noted)
- Disliked: Lack of results (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes PCA SKIN ExLinea Pro Peptide Serum a great fit for combination skin?

PCA SKIN ExLinea Pro Peptide Serum is a great fit for combination skin because it uses glycerin and betaine to keep your skin hydrated while peptides like acetyl hexapeptide-8 help smooth out fine lines. It is safe for your skin type and is unlikely to cause irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Which ingredients make this serum a good fit for combination skin?

Glycerin and Betaine make this serum a great fit because they hydrate your skin, while Acetyl Octapeptide-3 and Acetyl Hexapeptide-8 help support skin structure and reduce fine lines. These ingredients offer excellent suitability with a very low likelihood of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### What does Acetyl Octapeptide-3 do for combination skin?

Acetyl Octapeptide-3 helps smooth the look of lines and expression wrinkles on combination skin by relaxing surface tension. It is unlikely to feel greasy while supporting a firmer and softer feel.
Sources: [International Journal of Cosmetic Science, 2002](https://pubmed.ncbi.nlm.nih.gov/18498523/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31134751/)

### What does Argireline do for combination skin?

Argireline helps smooth out lines and keeps combination skin feeling soft when applied twice daily. This ingredient may reduce wrinkle depth and improve overall skin texture, though its absorption through the skin is quite low.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in your evening routine, applied after cleansing and before moisturizing. Putting treatments in the evening keeps things simple and helps avoid any sun exposure concerns.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to give your combination skin deep hydration, followed by your retinol. This pairing helps smooth fine lines while minimizing the dryness that retinol can sometimes cause, and it is unlikely to irritate your skin.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. Using it regularly helps smooth fine lines and keep your combination skin hydrated, and it is unlikely to cause irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause breakouts or clog pores on combination skin, as the formulation is safe and free of harsh ingredients that typically trigger irritation. It helps keep skin smooth and hydrated while supporting skin structure.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — €18.25 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/fr/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €35.99 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/fr/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €389.34 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice RESIST Perfectly Balanced Foaming Cleanser](https://lovi.care/skincare/fr/p/paula-s-choice/perfectly-balanced-foaming-cleanser/for/combination-skin) — Superior fit — €32.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/fr/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/fr/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — €17.47 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Pentylene Glycol, Glyceryl Isostearate, Isostearyl Isostearate, C13-15 Alkane, Betaine, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Methyl Gluceth-20, Rice Starch, Polyglyceryl-3 Laurate, Sodium Levulinate, Caprylyl Glycol, Levulinic Acid, Polyglyceryl-6 Oleate, Hydrolyzed Wheat Protein, Ethylhexylglycerin, Hydrolyzed Soy Protein, Sodium Hydroxide, Tetrasodium Glutamate Diacetate, Butylene Glycol, Pectin, Hydroxyethylcellulose, Arginine, Proline, Serine, Glucose, Acetyl Octapeptide-3, Bacillus Soybean Extract Ferment, Sodium Hyaluronate, Chondrus Crispus Extract, Acetyl Hexapeptide-8, Disodium Phosphate, Polysorbate 60, Sodium Phosphate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin (this page)
- Italy: https://lovi.care/skincare/it/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin