# MEDIPEEL PEPTIDE 9 VITANOL CREAM PRO for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: MEDIPEEL
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Excellent suitability for your normal skin is provided by the superb combination of ingredients like Niacinamide and Hyaluronic Acids, which offer humectant action and barrier repair, alongside a high concentration of peptides for collagen stimulation and ECM synthesis.
- The formula offers relevant benefits for wrinkles and fine lines due to the presence of peptides and retinol in concentrations that support anti-aging functions.
- There are no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Liposomal Vitamin Complex Vitanol, 9 Peptides

## What the research says

- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical application of retinol and retinoic acid both increased epidermal thickness and upregulated collagen genes and proteins in human skin, with retinol producing similar histological and molecular changes to retinoic acid alongside a significant reduction in facial wrinkles after 12 weeks. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))

## What reviewers say

Users find this cream to be a rich, moisturizing solution that provides a healthy glow, particularly beneficial for dry skin and during winter. Many users report positive effects on skin brightness and firmness. However, individuals with oily skin often find the texture too heavy, and some users expected faster whitening results considering the price.

- Liked: Deep nourishment (often mentioned)
- Liked: Pleasant texture/scent (often mentioned)
- Liked: Anti-aging effects (sometimes noted)
- Liked: Brightening & glow (sometimes noted)
- Disliked: Too heavy/greasy (sometimes noted)
- Liked: Quality packaging (rarely noted)
- Disliked: High price (rarely noted)
- Disliked: Potential breakouts (rarely noted)
- Disliked: Slow whitening results (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes MEDIPEEL Peptide 9 Vitanol Cream Pro a great fit for mature skin?

This cream is a great fit for mature skin because it combines Niacinamide and hyaluronic acids to plump and repair the skin barrier, alongside a high concentration of peptides and vitamin A to stimulate collagen and smooth out fine lines and wrinkles. It is unlikely to cause irritation for normal skin due to the absence of harsh ingredients.
Sources: [Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/)

### Which ingredients make this cream a good fit for mature skin?

This cream is a great fit for mature skin because it contains Niacinamide and hyaluronic acids to keep skin hydrated and repair the skin barrier, alongside peptides and retinol to help smooth fine lines and wrinkles. These ingredients work together to support collagen production and improve the overall look of aging skin without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Liposomal Vitamin Complex do for mature skin?

Liposomal Vitamin Complex helps smooth mature skin by softening fine lines and boosting firmness over time. It delivers active ingredients deeply to improve skin texture, though it may occasionally cause mild dryness or stinging when you first start using it.
Sources: [Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/)

### Where does this cream go in a skincare routine for mature skin?

This moisturizing treatment goes near the end of your evening routine, right after your treatment step, and works as the third step in the morning before sunscreen. It helps keep your skin soft and smooth while supporting collagen production and reducing fine lines.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/)

### Can I use this cream with retinol, and in what order?

Yes, you can use this moisturizing treatment alongside retinol because the formula is well-suited and safe for your mature skin without harsh ingredients that cause irritation. Apply your retinol product first and follow with this cream to help keep your skin comfortable and smooth.
Sources: [Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/)

### How often should I use this cream?

This cream is a great fit for your mature skin and can be used daily as part of your routine. Applying it regularly helps keep your skin soft and smooth while supporting collagen production and reducing fine lines.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to clog pores or cause breakouts for mature skin, as it has a negligible risk of causing blemishes according to reviewer feedback and lacks harsh ingredients. It helps keep skin smooth and firm while supporting a healthy moisture barrier without triggering irritation.

### Can I use this cream around the eyes or on my body?

Yes, you can use this moisturizing treatment around the eyes and on your body, though the skin on the body and the very thin skin around the eyes absorb products differently than facial skin. The gentle formula makes it unlikely to cause irritation while helping to smooth lines and keep skin soft.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — €20.46 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/fr/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — €95.00 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-96-mucin-power-essence/for/mature-skin) — Superior fit — €14.90 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/mature-skin) — Superior fit — €28.02 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €18.45 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/fr/p/torriden/dive-in-mild-sunscreen/for/mature-skin) — Superior fit — €24.00 at Amazon

## Where to buy

- Amazon.fr: €19.09 (https://www.amazon.fr/dp/B0D6WGZCRD?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- Notino: €23.50 (https://www.notino.fr/medipeel/peptide-9-vitanol-cream-pro-creme-unifiante-anti-signes-de-vieillissement/p-16400439/)
Prices checked 10 Oct – 4 Nov 2026.

## Ingredients

Niacinamide, Chinese Bellflower Root Extract, Liposomal Vitamin Complex Vitanol, 9 Peptides, Adenosine, Patented Redsnow Complex, Eosidin, Ectoin, Hyaluronic Acids Of Different Molecular Weights, Vitamin A, Collagen, Hippophae Rhamnoides Fruit Extract, Jojoba Seed Oil, Alpha-Bisabolol, Carbomer, Methylpropanediol, Hyaluronic Acid, Tromethamine, Hydrolyzed Hyaluronic Acid, Phaseolus Radiatus Seed Extract, Glycerin, Pentylene Glycol, Betaine, Pumpkin Seed Extract, Polygonum Fagopyrum Seed Extract, Punica Granatum Fruit Extract, Glucosylrutin, Hydrogenated Ethylhexyl Olivate, Disodium Edta, Palm Oil, Polyglutamic Acid, Belamcanda Chinensis Root Extract, Ethylhexylglycerin, Hydrogenated Lecithin, Hydrogenated Olive Oil, Caprylic Capric Triglyceride, Astaxanthin Extract, Lactobacillus Ferment, Salicylic Acid, Sucrose Palmitate, Citric Acid, Retinyl Palmitate, Tocopherol, Menadione, Polyglyceryl-4 Oleate, Glutathione, Artemisia Annua Extract, Linoleic Acid, Phaeodactylum Tricornutum Extract, Helianthus Annuus Seed Oil Sunflower Seed Oil, Arachis Hypogaea Oil, Camellia Japonica Flower Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Citrus Unshiu Peel Extract, Linolenic Acid, Coconut Oil, Alteromonas Extract Ferment, Phenethyl Alcohol, Polyglyceryl-10 Laurate, Olea Europaea Oil Fruit Olive Oil Fruit, Ascorbic Acid, Chlorella Minutissima Extract, Caprylyl Glycol, Sodium Phosphate, Lecithin, Retinal, Copper Tripeptide-1, Acetyl Hexapeptide-8, Oligopeptide-29, Palmitoyl Pentapeptide-4, Acetyl Octapeptide-3, Oligopeptide-32, Oligopeptide-6, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-10
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- France: https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin (this page)
- Italy: https://lovi.care/skincare/it/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin