# Mederma PM Intensive Overnight Scar Cream for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Mederma](https://lovi.care/skincare/fr/brands/mederma)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for sensitive skin.

## Why this fit

- Highly suitable for your normal skin, this product utilizes glycerin and panthenol to maintain hydration and support barrier repair, while onion bulb extract and copper tripeptide-1 work to improve skin texture and reduce the appearance of scars.
- Aloe Barbadensis Leaf and panthenol offer supportive hydration and soothing benefits, which are beneficial for your redness and irritation concerns.
- The formulation is safe for your sensitive skin, as it lacks prohibited or harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Dimethicone, Onion Bulb Extract, Copper Tripeptide-1, Aloe Barbadensis Leaf, Hydrolyzed Collagen

## What the research says

- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Topical onion extract improved scar colour compared to silicon gel, while silicon gel was superior in decreasing scar height in 60 patients with hypertrophic and keloid scars, with the most effective results obtained from combining onion extract and silicon gel. ([Journal of Wound Care, 2007](https://pubmed.ncbi.nlm.nih.gov/17722521/))
- Silicone derivative plus onion extract gel reduced pain, itching, and pigmentation compared to placebo in patients after median sternotomy. ([International Wound Journal, 2012](https://pubmed.ncbi.nlm.nih.gov/22168750/))
- Topical 12% onion extract gel applied early on Pfannenstiel's cesarean section scars in Asians improved scar height and scar symptoms compared to placebo, with no significant difference in scar redness, pliability, or overall appearance. ([Dermatology Research and Practice, 2012](https://pubmed.ncbi.nlm.nih.gov/22924037/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## What reviewers say

Based on a very large amount of data, users report this cream is effective at softening and flattening scars from surgery, acne, and injuries with consistent use over months. Many appreciate the convenient, non-greasy application. However, results can take a long time to become noticeable, and a significant number of users find the scent unpleasant.

- Liked: Effective on scars (often mentioned)
- Disliked: Slow results (often mentioned)
- Disliked: Unpleasant smell (often mentioned)
- Liked: Convenient application (sometimes noted)
- Liked: Good absorption (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Price vs quantity (sometimes noted)
- Disliked: Skin reactions (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Mederma PM Intensive Overnight Scar Cream a great fit for sensitive skin?

Mederma PM Intensive Overnight Scar Cream is a great fit for sensitive skin because it uses glycerin and panthenol to maintain hydration and support barrier repair, while aloe barbadensis leaf provides soothing benefits that help calm redness and irritation. Additionally, the formulation is safe and unlikely to cause irritation as it lacks harsh ingredients.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Which ingredients make this cream a good fit for sensitive skin?

This cream is a great fit for sensitive skin because it uses aloe vera leaf and panthenol to soothe and calm irritation and redness. It also includes glycerin to keep your skin hydrated and help repair your skin barrier safely without harsh ingredients.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### What does Dimethicone do for sensitive skin?

Dimethicone helps protect sensitive skin against irritants and can keep it feeling calm and comfortable. It is generally well tolerated and unlikely to cause adverse reactions on delicate or reactive skin.
Sources: [Ostomy/wound Management, 2005](https://pubmed.ncbi.nlm.nih.gov/16439809/), [Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/)

### What does Onion Bulb Extract do for sensitive skin?

Onion extract helps calm redness and irritation while improving overall skin texture and softness in sensitive skin. It may also support the skin barrier, making it less prone to discomfort.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40177799/), [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22768353/)

### Where does it go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. It is safe for your sensitive skin because it lacks harsh ingredients that may cause irritation.

### Can I use this cream with retinol, and in what order?

You can use this cream in your evening routine after applying your retinol, letting the retinol absorb first. This product is unlikely to cause irritation on sensitive skin because it lacks harsh ingredients and includes soothing aloe vera and panthenol.

### How often should I use it?

Apply this treatment in your evening routine. It is safe for sensitive skin and uses ingredients that help keep skin calm and hydrated while improving texture.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts on sensitive skin, as its formulation lacks harsh or irritating ingredients. It uses gentle, soothing components like aloe and panthenol that help keep skin calm and hydrated without triggering reactions.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is it fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol and isopropyl alcohol).

## Alternatives for sensitive skin

- [SKIN1004 Madagascar Centella Asiatica Ampoule](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-asiatica-ampoule/for/sensitive-skin) — High fit — €20.37 at Amazon
- [Purito Galacto Niacin 97 Power Essence](https://lovi.care/skincare/fr/p/purito/galacto-niacin-97-power-essence/for/sensitive-skin) — Average fit — €18.85 at Amazon
- [Clarins Double Serum](https://lovi.care/skincare/fr/p/clarins/double-serum/for/sensitive-skin) — High fit — €57.50 at Notino

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €28.02 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/fr/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €27.60 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/fr/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — €24.00 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Cetearyl Alcohol, Glycerin, C12-15 Alkyl Benzoate, Dicaprylyl Carbonate, Pentylene Glycol, Cyclomethicone, Arachidyl Alcohol, Alcohol, Behenyl Alcohol, Arachidyl Glucoside, Onion Bulb Extract, Copper Tripeptide-1, Aloe Barbadensis Leaf, Cetearyl Glucoside, Tocopheryl Acetate, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyethylcellulose, Hydrolyzed Soy Protein, Glycine, Panthenol, Hydrolyzed Collagen, Peg-400, Arginine Hcl, Leucine, Lysine Hydrochloride, Alanine, Sodium Lactate, Aspartic Acid, Glucose, Glutamic Acid, Isopropyl Alcohol, Mannitol, Sorbitol, Tromethamine, Valine, Histidine Hydrochloride, Isoleucine, Phenylalanine, Tyrosine, Potassium Sorbate, Sodium Benzoate, Citric Acid, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin (this page)
- Italy: https://lovi.care/skincare/it/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin