# Lancôme Advanced Génifique Night Cream for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Lancôme](https://lovi.care/skincare/fr/brands/lancome)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few moisturizers fit it even better.

## Why this fit

- This product is highly suitable for your normal skin, as Bifida Ferment Lysate and Glycerin work synergistically to repair the skin barrier and provide essential hydration. These ingredients offer general soothing benefits that can help with your redness and irritation.
- The formulation includes Sodium Hyaluronate and Adenosine, which further enhance skin barrier resilience and hydration, supporting overall skin health.
- The safety profile is excellent, with no risks of irritation for your sensitive skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Bifida Lysate Ferment, Adenosine, Sodium Hyaluronate, Ceramide Np, Ascorbyl Glucoside

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))
- Adenosine treatment of dermal papilla cells upregulates fibroblast growth factor-7 expression via the A2b adenosine receptor and intracellular cAMP signaling, and fibroblast growth factor-7 significantly stimulates hair fiber elongation in human scalp hair follicle organ cultures. ([The Journal of Investigative Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17301835/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## What reviewers say

Based on a very large amount of data, this product is highly regarded for its ability to deeply hydrate dry and aging skin, effectively repair the moisture barrier, and leave the complexion feeling plump, smooth, and radiant by morning. It is frequently noted for reducing the appearance of fine lines and smoothing the skin texture. While most users find it absorbs quickly without a greasy feel, a small number of individuals with sensitive skin have reported experiencing breakouts or irritation, and some dislike the fragrance.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Absorbs quickly (often mentioned)
- Liked: Softens and smooths (often mentioned)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Skin irritation (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Lancôme Advanced Génifique Night Cream a great fit for sensitive skin?

Lancôme Advanced Génifique Night Cream is a great fit for sensitive skin because it uses ingredients like Bifida Lysate Ferment, glycerin, sodium hyaluronate, and ceramides to repair the skin barrier and keep skin hydrated. It is very unlikely to cause irritation because the formula avoids harsh components and includes soothing ingredients that help calm redness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for sensitive skin?

Bifida Lysate Ferment, glycerin, sodium hyaluronate, ceramide NP, and adenosine make this cream a great fit by repairing the skin barrier, keeping skin hydrated, and soothing redness without harsh ingredients that might trigger irritation.
Sources: [International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/)

### What does Bifida Ferment Lysate do for sensitive skin?

Bifida Ferment Lysate helps calm reactive skin, making it less sensitive and more resistant to daily irritation and physical or chemical aggression. It achieves this by strengthening your skin barrier and keeping moisture locked in while decreasing redness.
Sources: [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/), [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/)

### What does Adenosine do for sensitive skin?

Adenosine helps calm sensitive skin while reducing wrinkles and improving smoothness. This ingredient is generally well tolerated, making it unlikely to cause irritation when used in your daily routine.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/)

### Where does this cream go in a skincare routine for sensitive skin?

This cream goes in your evening routine as a moisturizing treatment, applied after your cleanser and soothing toner. It is unlikely to cause irritation for your sensitive skin because it leaves out harsh ingredients and includes soothing components.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying it after your retinol treatment to help soothe your skin and keep it hydrated. This routine is unlikely to cause irritation because the formula has an excellent safety profile and contains barrier-supporting ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/)

### How often should I use this cream?

This cream is a great fit for your sensitive skin and can be used in your evening routine as a moisturizing treatment. Its gentle ingredients are unlikely to cause irritation and help keep your skin calm and hydrated.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to cause breakouts or clogged pores for sensitive skin, as it has an excellent safety profile with a very low risk of irritation and no harsh ingredients. Reviewers rarely report breakouts from this product.

### Can I use this cream around the eyes or on my body?

You can use this cream safely around your eyes and on your body to hydrate and smooth those areas. The formula has an excellent safety profile with no harsh ingredients, making it very gentle and unlikely to cause irritation on delicate skin.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (linalool, limonene, citronellol, and parfum). Behenyl alcohol and cetyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — €20.46 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-96-mucin-power-essence/for/sensitive-skin) — Superior fit — €14.90 at Amazon
- [COSRX Advanced Snail 92 All in One Cream](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — €16.94 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €28.02 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/fr/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €27.60 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/fr/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — €24.00 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Bifida Lysate Ferment, Glycerin, Dicaprylyl Ether, Pentylene Glycol, Polyglyceryl-6 Distearate, Propanediol, Cetyl Esters, Jojoba Esters, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Octyldodecanol, Acacia Decurrens Flower Cera, Acacia Decurrens Wax Flower, Helianthus Annuus Seed Cera, Sunflower Wax Seed, Helianthus Annuus Seed Oil, Sunflower Seed Oil, Polymnia Sonchifolia Root Juice, Ceramide Np, Alpha-Glucan Oligosaccharide, Sodium Hyaluronate, Sodium Hydroxide, Sodium Stearoyl Glutamate, Salicyloyl Phytosphingosine, 2-Oleamido-1, 3-Octadecanediol, Adenosine, Mannose, Coco-Caprylate Caprate, Ascorbyl Glucoside, Hydroxyacetophenone, Hydroxypalmitoyl Sphinganine, Hydroxypropyl Phosphate Starch, Capryloyl Salicylic Acid, Trisodium Ethylenediamine Disuccinate, Lactic Acid, Lactobacillus, Acetic Acid, Maltodextrin, Yeast Extract, Extrait De Levure, Polyglycerin-3, Polyglyceryl-3 Beeswax, Cetyl Alcohol, Tocopherol, Sodium Benzoate, Linalool, Limonene, Citronellol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/lancome/advanced-genifique-night-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/lancome/advanced-genifique-night-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/lancome/advanced-genifique-night-cream/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/lancome/advanced-genifique-night-cream/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/sensitive-skin (this page)
- Italy: https://lovi.care/skincare/it/p/lancome/advanced-genifique-night-cream/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/lancome/advanced-genifique-night-cream/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/lancome/advanced-genifique-night-cream/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/lancome/advanced-genifique-night-cream/for/sensitive-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/lancome/advanced-genifique-night-cream/for/sensitive-skin