# Lancôme Advanced Génifique Night Cream for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Lancôme](https://lovi.care/skincare/fr/brands/lancome)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your oily skin, as Bifida Lysate Ferment and Glycerin provide some barrier repair and hydration, but it lacks sufficient ingredients for optimal oil control to address your main goals of managing acne and breakouts.
- The formula provides excellent moisturizing and treatment due to bifida ferment lysate and sodium hyaluronate, enhancing barrier resilience and hydration, which are generally beneficial but not targeted for your specific concerns.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing agents like Bifida Lysate Ferment and Alpha-Glucan Oligosaccharide.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Bifida Lysate Ferment, Adenosine, Sodium Hyaluronate, Ceramide Np, Ascorbyl Glucoside

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## Why other moisturizers fit oily acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28342238/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

Based on a very large amount of data, this product is highly regarded for its ability to deeply hydrate dry and aging skin, effectively repair the moisture barrier, and leave the complexion feeling plump, smooth, and radiant by morning. It is frequently noted for reducing the appearance of fine lines and smoothing the skin texture. While most users find it absorbs quickly without a greasy feel, a small number of individuals with sensitive skin have reported experiencing breakouts or irritation, and some dislike the fragrance.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Absorbs quickly (often mentioned)
- Liked: Softens and smooths (often mentioned)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Skin irritation (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Lancôme Advanced Génifique Night Cream work for oily acne-prone skin?

This cream is an average fit for oily acne-prone skin because while it provides good hydration and barrier repair, it lacks the ingredients needed for oil control to manage breakouts. To work better for this skin type, a product needs lightweight ingredients that provide hydration and target blemishes without clogging pores or adding excess oil.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Bifida Lysate Ferment, glycerin, and sodium hyaluronate make this cream a good fit by providing hydration and barrier repair without irritation. However, because this product only offers an average fit for oily acne-prone skin, a product of this type needs targeted oil-control ingredients, lightweight textures that do not clog pores, and blemish-managing agents to properly balance oil and breakouts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Bifida Ferment Lysate do for oily acne-prone skin?

Bifida Ferment Lysate helps calm oily acne-prone skin by strengthening your skin barrier and lowering irritation. It is unlikely to clog pores and may help keep your skin feeling smooth and balanced.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### What does Adenosine do for oily acne-prone skin?

Adenosine helps calm oily, acne-prone skin and supports a smooth, balanced look. It is generally well-tolerated and is unlikely to clog pores or cause irritation.
Sources: [International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/), [The Journal of Clinical Investigation, 2014](https://pubmed.ncbi.nlm.nih.gov/25061872/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This cream goes in the evening routine as a moisturizing treatment, applied after your cleansing toner and before your daytime or nighttime moisturizer. To truly fit oily acne-prone skin well, a product of this type needs dedicated oil-control and blemish-managing ingredients.

### Can I use this cream with retinol, and in what order?

You can use this cream in your evening routine after applying retinol, as its soothing ingredients help keep your skin calm. Oily acne-prone skin needs a product of this type that also balances oil and targets breakouts.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice a day to keep your skin hydrated and support your skin barrier. Applying it regularly is unlikely to cause irritation on oily skin, though an oily acne-prone skin type needs a product with targeted oil-control ingredients to help manage breakouts.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to cause irritation or breakouts on your oily skin, as it has a very safe formula with soothing ingredients and a low rate of complaints. However, because it lacks sufficient oil-control ingredients to properly manage breakouts, oily acne-prone skin needs a product that includes targeted oil-balancing and blemish-clearing ingredients.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on your body, as its very safe formula with soothing agents is unlikely to cause irritation. However, oily acne-prone skin needs products with targeted oil control and blemish-clearing ingredients to properly manage breakouts in those areas.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (linalool, limonene, citronellol, and parfum). Behenyl alcohol and cetyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — €14.90 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/fr/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — €17.90 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/fr/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — €22.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/fr/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €11.35 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/fr/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/fr/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — €34.30 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Bifida Lysate Ferment, Glycerin, Dicaprylyl Ether, Pentylene Glycol, Polyglyceryl-6 Distearate, Propanediol, Cetyl Esters, Jojoba Esters, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Octyldodecanol, Acacia Decurrens Flower Cera, Acacia Decurrens Wax Flower, Helianthus Annuus Seed Cera, Sunflower Wax Seed, Helianthus Annuus Seed Oil, Sunflower Seed Oil, Polymnia Sonchifolia Root Juice, Ceramide Np, Alpha-Glucan Oligosaccharide, Sodium Hyaluronate, Sodium Hydroxide, Sodium Stearoyl Glutamate, Salicyloyl Phytosphingosine, 2-Oleamido-1, 3-Octadecanediol, Adenosine, Mannose, Coco-Caprylate Caprate, Ascorbyl Glucoside, Hydroxyacetophenone, Hydroxypalmitoyl Sphinganine, Hydroxypropyl Phosphate Starch, Capryloyl Salicylic Acid, Trisodium Ethylenediamine Disuccinate, Lactic Acid, Lactobacillus, Acetic Acid, Maltodextrin, Yeast Extract, Extrait De Levure, Polyglycerin-3, Polyglyceryl-3 Beeswax, Cetyl Alcohol, Tocopherol, Sodium Benzoate, Linalool, Limonene, Citronellol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/lancome/advanced-genifique-night-cream/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/lancome/advanced-genifique-night-cream/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/lancome/advanced-genifique-night-cream/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/lancome/advanced-genifique-night-cream/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/oily-acne-prone-skin (this page)
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