# Lancôme Advanced Génifique Night Cream for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Lancôme](https://lovi.care/skincare/fr/brands/lancome)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate benefits for your dry and sensitive skin, as bifida ferment lysate and sodium hyaluronate provide excellent hydration and barrier support. Glycerin and ceramide NP further enhance moisture retention and repair, making it generally suitable for dry or flaky skin.
- While the formula offers good general skincare benefits, it lacks specialized ingredients to directly address your primary concern of dryness and flakiness.
- The product is safe for your dry and sensitive skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Bifida Lysate Ferment, Adenosine, Sodium Hyaluronate, Ceramide Np, Ascorbyl Glucoside

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## Why other moisturizers fit dry sensitive skin better

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Nanoemulsions containing Macadamia integrifolia seed oil successfully enhanced skin hydration and reduced wrinkles in human volunteers, outperforming conventional emulsions in skin hydration enhancement. ([Nanomaterials, 2024](https://pubmed.ncbi.nlm.nih.gov/38668218/))

## What reviewers say

Based on a very large amount of data, this product is highly regarded for its ability to deeply hydrate dry and aging skin, effectively repair the moisture barrier, and leave the complexion feeling plump, smooth, and radiant by morning. It is frequently noted for reducing the appearance of fine lines and smoothing the skin texture. While most users find it absorbs quickly without a greasy feel, a small number of individuals with sensitive skin have reported experiencing breakouts or irritation, and some dislike the fragrance.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Absorbs quickly (often mentioned)
- Liked: Softens and smooths (often mentioned)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Skin irritation (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Lancôme Advanced Génifique Night Cream work for dry sensitive skin?

This cream works moderately well for dry and sensitive skin because ingredients like sodium hyaluronate and ceramide NP help keep skin hydrated and repair the skin barrier. However, it lacks specialized ingredients to directly tackle deep dryness and flakiness. A product of this type needs rich, highly effective soothing ingredients, humectants, and barrier-supporting components that provide deep hydration and nourishment without any risk of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for dry sensitive skin?

This cream works for dry sensitive skin because bifida ferment lysate, sodium hyaluronate, glycerin, and ceramide NP help hydrate the skin and support its barrier. To fit this skin even better, a moisturizing treatment needs extra nourishing ingredients and soothing agents that directly target dryness and flakiness without any risk of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Bifida Ferment Lysate do for dry sensitive skin?

Bifida Ferment Lysate helps soothe dry sensitive skin by calming irritation and keeping moisture locked in. It strengthens your skin barrier so it stays soft and smooth against everyday stress. Using a product with this ingredient may also lower redness and keep your skin comfortable.
Sources: [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### What does Adenosine do for dry sensitive skin?

Adenosine helps calm dry sensitive skin by improving moisture, barrier strength, and overall comfort. It is unlikely to cause irritation and may help smooth out fine lines while keeping the skin soft and hydrated.
Sources: [International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This moisturizing treatment goes in the evening routine after your toner and before your moisturizer. A product of this type needs specialized rich ingredients and extra barrier-repairing elements to fully soothe and comfort dry skin.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying your retinol first and following it with this cream. This order helps keep your skin comfortable and minimizes dryness when using strong active ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment in the evening as part of your nightly routine. Daily application helps improve skin moisture and supports the skin barrier, though a product of this type for dry and sensitive skin also needs richer moisturizing ingredients to fully address dryness and flakiness.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to cause breakouts or clogged pores for dry sensitive skin, as reviewer complaints about breakouts are low and the formula lacks harsh ingredients. It brings moderate hydration with ingredients like sodium hyaluronate and glycerin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream around the eyes or on my body?

You can use this cream on your body, but the skin around the eyes is much thinner than body skin and may need specialized products. This cream is safe for dry and sensitive skin without irritation risks, though a product of this type needs richer hydrators and barrier-repairing ingredients to fully address severe dryness and flakiness.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (linalool, limonene, citronellol, and parfum). Behenyl alcohol and cetyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for dry sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-sensitive-skin) — Superior fit — €20.46 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/fr/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-sensitive-skin) — Superior fit — €13.11 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/fr/p/l-occitane/immortelle-divine-cream/for/dry-sensitive-skin) — Superior fit — €95.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/fr/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €7.50 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/fr/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €18.79 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/fr/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €29.95 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Bifida Lysate Ferment, Glycerin, Dicaprylyl Ether, Pentylene Glycol, Polyglyceryl-6 Distearate, Propanediol, Cetyl Esters, Jojoba Esters, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Octyldodecanol, Acacia Decurrens Flower Cera, Acacia Decurrens Wax Flower, Helianthus Annuus Seed Cera, Sunflower Wax Seed, Helianthus Annuus Seed Oil, Sunflower Seed Oil, Polymnia Sonchifolia Root Juice, Ceramide Np, Alpha-Glucan Oligosaccharide, Sodium Hyaluronate, Sodium Hydroxide, Sodium Stearoyl Glutamate, Salicyloyl Phytosphingosine, 2-Oleamido-1, 3-Octadecanediol, Adenosine, Mannose, Coco-Caprylate Caprate, Ascorbyl Glucoside, Hydroxyacetophenone, Hydroxypalmitoyl Sphinganine, Hydroxypropyl Phosphate Starch, Capryloyl Salicylic Acid, Trisodium Ethylenediamine Disuccinate, Lactic Acid, Lactobacillus, Acetic Acid, Maltodextrin, Yeast Extract, Extrait De Levure, Polyglycerin-3, Polyglyceryl-3 Beeswax, Cetyl Alcohol, Tocopherol, Sodium Benzoate, Linalool, Limonene, Citronellol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin (this page)
- Italy: https://lovi.care/skincare/it/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/lancome/advanced-genifique-night-cream/for/dry-sensitive-skin