# La Roche-Posay Hyalu B5 Serum for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [La Roche-Posay](https://lovi.care/skincare/fr/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Offers moderate moisturizing for your dry and sensitive skin due to the presence of glycerin and panthenol, which hydrate and enhance barrier resilience.
- Sodium hyaluronate and hydrolyzed hyaluronic acid provide additional humectant action, supporting overall skin hydration.
- The formula is safe for your skin, as it lacks prohibited or harsh ingredients and poses no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Vitamin B5, Madecassoside, Thermal Spring Water

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))

## What reviewers say

Based on a very large amount of data, this serum is highly praised for its intense hydration and ability to visibly plump the skin, leading to immediate improvements in bounce and a reduction in fine dehydration lines. While many users with sensitive skin find it gentle and soothing, a significant number dislike its strong floral fragrance and sticky finish.

- Liked: Intense hydration (mostly mentioned)
- Liked: Smoothes fine lines (often mentioned)
- Disliked: Strong fragrance (often mentioned)
- Liked: Fast absorption (sometimes noted)
- Liked: Gentle on sensitive skin (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes La Roche-Posay Hyalu B5 a great fit for dry sensitive skin?

La Roche-Posay Hyalu B5 Serum is a great fit because it uses glycerin and panthenol to hydrate your dry skin and strengthen its natural barrier, while sodium hyaluronate provides extra moisture. The formula is safe for your delicate skin, as it contains no harsh ingredients and is unlikely to cause irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Glycerin and panthenol make this serum a great fit by providing moderate moisture and helping keep your delicate barrier strong, while sodium hyaluronate adds extra hydration. The gentle formula is also very safe for your skin and poses no risk of irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### What does Panthenol do for dry sensitive skin?

Panthenol helps soothe dry sensitive skin by calming redness and keeping it deeply hydrated. It improves moisture retention and supports skin barrier recovery, making irritated skin feel much more comfortable and soft.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in your evening routine after your cleanser and soothing toner, and before your moisturizer. Putting treatments in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate and calm dry sensitive skin, followed by your retinol product. This helps keep your skin comfortable and supports barrier resilience while you use active ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

You can use this serum in the evening as part of your regular routine, applying it after your toner and before your moisturizer. Daily application helps keep dry and sensitive skin hydrated and supports a calm, smooth feel.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts for dry sensitive skin because its formula avoids heavy, pore-clogging ingredients. Reviewers occasionally mention a sticky texture or strong fragrance, but skin irritation remains low.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this serum around the eyes or on my body?

You can use this serum around the eyes and on the body because its gentle formula hydrates and calms dry skin without causing irritation. The ingredients help improve skin moisture and support the skin barrier in delicate areas.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for dry sensitive skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/fr/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-sensitive-skin) — Superior fit — €17.99 at Amazon
- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/fr/p/revision-skincare/hydrating-serum/for/dry-sensitive-skin) — High fit — €191.05 at Amazon
- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/fr/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/dry-sensitive-skin) — High fit — €29.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/fr/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €7.50 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/fr/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €18.79 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/fr/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €29.95 at Amazon

## Where to buy

- Amazon.fr: €40.00 (https://www.amazon.fr/dp/B0CZ3WBPTJ?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
- Notino: €28.90 (https://www.notino.fr/la-roche-posay/hyalu-b5-serum-anti-rides/p-16328156/)
- Lookfantastic: €41.40 (https://www.lookfantastic.fr/p/la-roche-posay-hyalu-b5-suractivated-serum-30ml/17222049/)
Prices checked 10 Oct – 31 Oct 2026.

## Ingredients

Water, Glycerin, Alcohol Denat, Propylene Glycol, Panthenol, Pentylene Glycol, Dimethicone, Peg-6 Caprylic Capric Glycerides, Ppg-6-Decyltetradeceth-30, Glyceryl Isostearate, Madecassoside, Sodium Hyaluronate, Ammonium Polyacryloyldimethyl Taurate, Disodium Edta, Hydrolyzed Hyaluronic Acid, Caprylyl Glycol, Citric Acid, Xanthan Gum, Butylene Glycol, Tocopherol, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin (this page)
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/hyalu-b5-serum/for/dry-sensitive-skin