# La Roche-Posay Effaclar H Iso-Biome Moisturiser for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: Average · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [La Roche-Posay](https://lovi.care/skincare/fr/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/fr/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily skin; a few moisturizers fit it even better.

## Why this fit

- Offers excellent moisturizing for your oily skin due to the presence of glycerin and squalane, which hydrate and enhance barrier resilience.
- Niacinamide and capryloyl glycine provide moderate benefits for oily shine by helping to regulate sebum production, though more potent ingredients could optimize oil control.
- The formula is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-acne-prone-skin): High

## Key ingredients

Thermal Water, Niacinamide, Squalane, Panthenol, Vitreoscilla Ferment

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- A dermocosmetic formulation containing Vichy volcanic mineralizing water, Vitreoscilla filiformis extract, niacinamide, hyaluronic acid, and vitamin E accelerated skin renewal, improved antioxidant defenses, enhanced skin barrier recovery after acute stress, and improved microbiome recovery compared to untreated skin. ([Journal of the European Academy of Dermatology and Venereology, 2022](https://pubmed.ncbi.nlm.nih.gov/34979590/))
- The combination of Vitreoscilla filiformis extract and Vichy volcanic mineralizing water strengthens the skin barrier by stimulating skin differentiation and tight junctions, enhances biochemical defenses via antimicrobial peptides, and supports cellular immune defenses by increasing the IL-10/IL-12 ratio and protecting Langerhans cells from ultraviolet radiation compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2022](https://pubmed.ncbi.nlm.nih.gov/34979591/))

## What reviewers say

This moisturizer is frequently described as a lifesaver for oily, acne-prone skin, especially when weakened by treatments. Most users find it deeply soothing and non-greasy, though a notable number report issues with pilling or the product rolling off the skin, particularly under makeup.

- Liked: Soothing for compromised barriers (mostly mentioned)
- Liked: Gentle on sensitive skin (often mentioned)
- Liked: Non-greasy hydration (often mentioned)
- Disliked: Pilling and flaking (often mentioned)
- Liked: Reduces acne/blemishes (sometimes noted)
- Disliked: Inferior to old formula (sometimes noted)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Small size / High price (sometimes noted)
- Disliked: Stinging sensation (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine every day to keep your face fresh.
- Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
- Gently press a small amount into your skin and let it absorb fully.
- Apply on clean, slightly dry skin to help control that oily shine.
- Avoid the eye area and do a quick patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes La Roche-Posay Effaclar H Iso-Biome a great fit for oily skin?

La Roche-Posay Effaclar H Iso-Biome is a great fit for oily skin because it offers excellent hydration from ingredients like glycerin and squalane while keeping your skin safe with no risk of irritation. Niacinamide and capryloyl glycine also help manage oily shine by regulating sebum production.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for oily skin?

Glycerin and squalane make this cream a great fit for your oily skin by providing rich hydration, while niacinamide and capryloyl glycine help manage oily shine. These ingredients work together safely without harsh components, keeping your skin comfortable and balanced.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Thermal Water do for oily skin?

Thermal Water helps calm oily skin, keeps it comfortable, and reduces irritation. It provides light hydration without adding heaviness.
Sources: [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/), [International Journal of Biometeorology, 2025](https://pubmed.ncbi.nlm.nih.gov/40423748/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this cream go in a skincare routine for oily skin?

This moisturizer goes near the end of your routine, used after cleansing and toning in the morning and evening. It is safe for oily skin and helps keep it hydrated while managing shine without irritation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying the cream after your retinol product to help keep your skin comfortable and reduce dryness. Using a supportive moisturizer along with retinoids is safe and helps maintain skin barrier strength while you treat breakouts.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this cream?

You can use this moisturizing treatment daily as part of your morning and evening routine to keep your oily skin hydrated and balanced. Daily applications of this type of moisturizer significantly improve moisture levels and support the skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily skin?

This cream is unlikely to clog pores, cause breakouts, or lead to purging on oily skin, as its formula is safe and free of harsh or irritating ingredients.

### Can I use this cream around the eyes or on my body?

This cream is safe to use around the eyes and on the body because the skin around the eyes and in many body areas is thin and benefits from gentle, hydrating formulas like this one. Studies show that skin thickness varies significantly across the body, making gentle moisturizers suitable for delicate zones.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for oily skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/fr/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-skin) — Superior fit — €14.90 at Amazon
- [Anua Heartleaf 78% Soothing Cream](https://lovi.care/skincare/fr/p/anua/heartleaf-78-soothing-cream/for/oily-skin) — Superior fit — €16.98 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/fr/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-skin) — High fit — €17.90 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/fr/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €11.35 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/fr/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — €19.99 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/fr/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — €34.30 at Amazon

## Where to buy

- Notino: €22.60 (https://www.notino.fr/la-roche-posay/effaclar-h-creme-hydratante-anti-imperfections-de-la-peau-a-tendance-acneique/p-16128922/)
Prices checked 10 Oct 2026.

## Ingredients

Water, Glycerin, Squalane, Dimethicone, Panthenol, Zea Mays Corn Starch, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Myristyl Myristate, Bixa Orellana Seed Extract, Stearic Acid, Potassium Cetyl Phosphate, Glyceryl Stearate Se, Sodium Hydroxide, Myristic Acid, 2-Oleamido-1,3-Octadecanediol, Palmitic Acid, Hydroxyacetophenone, Capryloyl Glycine, Caprylyl Glycol, Vitreoscilla Ferment, Citric Acid, Maltodextrin, Xanthan Gum, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin (this page)
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/effaclar-h-iso-biome-moisturiser/for/oily-skin