# La Roche-Posay Cicaplast B5 Soothing Repairing Spray for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [La Roche-Posay](https://lovi.care/skincare/fr/brands/la-roche-posay)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this spray offers excellent skin repair with panthenol and madecassoside to enhance barrier resilience and address wrinkles and fine lines.
- Glycerin and panthenol provide humectant action, supporting your skin's hydration and repair processes.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components like panthenol and madecassoside.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/dark-spots): Superior
- [Mature skin](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/oily-acne-prone-skin): Superior

## Key ingredients

Panthenol, Madecassoside, Thermal Water, Glycerin, Copper Gluconate

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Zinc gluconate induced alpha2, alpha3, alphaV, and alpha6 integrins, copper gluconate induced alpha2, alpha6, and beta1, and manganese gluconate induced most studied integrins in cultured keratinocytes. ([The British Journal of Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10215764/))

## What reviewers say

Users frequently describe this spray as a go-to for compromised skin barriers, appreciating its ability to instantly calm redness and irritation without physical contact. It is highly effective for sensitive skin conditions and post-procedure healing, though some users note a slightly tacky finish and an occasionally aggressive spray.

- Liked: Touch-free application (mostly mentioned)
- Liked: Barrier repair healing (often mentioned)
- Liked: Instant soothing relief (often mentioned)
- Liked: Lightweight hydration (sometimes noted)
- Disliked: Aggressive spray (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Price to quantity (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes La Roche-Posay Cicaplast B5 Spray a great fit for mature skin?

La Roche-Posay Cicaplast B5 Spray is a great fit for mature skin because it uses panthenol and madecassoside to repair the skin barrier and help smooth out fine lines and wrinkles. Glycerin adds deep hydration, and the gentle formula is very unlikely to cause any irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this spray a good fit for mature skin?

Panthenol and madecassoside make this spray a great fit for mature skin by helping repair the skin barrier and smooth out fine lines and wrinkles. Glycerin also helps by adding moisture, while panthenol, madecassoside, and thermal water keep the safety profile high and soothe the skin without irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Panthenol do for mature skin?

Panthenol helps mature skin by increasing moisture and reducing water loss, which makes the skin feel softer and smoother. It also improves elasticity and reduces the appearance of wrinkles while soothing irritation.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29577586/), [Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/)

### What does Madecassoside do for mature skin?

Madecassoside helps mature skin by supporting collagen production to keep skin firm and smooth while calming irritation. It is unlikely to cause irritation and may protect against signs of aging and sun damage.
Sources: [Journal of Medicinal Food, 2023](https://pubmed.ncbi.nlm.nih.gov/37976111/), [Annales Pharmaceutiques Francaises, 1995](https://pubmed.ncbi.nlm.nih.gov/7741425/)

### Where does this spray go in a skincare routine for mature skin?

This spray is a treatment that goes in your evening routine after cleansing and before your moisturizer. It is very gentle on mature skin, helping to smooth out fine lines and keep your skin feeling soft and well hydrated.

### Can I use this spray with retinol, and in what order?

You can use this spray alongside retinol by applying the spray first to keep your skin calm and hydrated before layering your retinol product. This spray is unlikely to cause irritation and helps support your skin barrier while you use active treatments.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use this spray?

This treatment spray fits into your evening routine as a nightly step after cleansing and toning. It helps repair your skin barrier, keeps it soft and hydrated, and is very unlikely to cause irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can this spray clog pores, cause breakouts or purging for mature skin?

This spray is unlikely to clog pores or cause breakouts for mature skin, as it has a very safe formula with soothing ingredients that calm the skin without harsh additives. It helps keep your skin feeling smooth and comfortable without heavy oils that can block pores.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this spray fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Vichy Mineralizing Thermal Water](https://lovi.care/skincare/fr/p/vichy/mineralizing-thermal-water/for/mature-skin) — High fit — €8.25 at Amazon
- [Mario Badescu Facial Spray with Aloe, Chamomile and Lavender](https://lovi.care/skincare/fr/p/mario-badescu/facial-spray-with-aloe-chamomile-and-lavender/for/mature-skin) — High fit — €6.90 at Notino
- [BIOHEAL BOH Panthenol Cica Barrier Cream Mist](https://lovi.care/skincare/fr/p/bioheal-boh/panthenol-cica-barrier-cream-mist/for/mature-skin) — High fit — €20.00 at Notino

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/mature-skin) — Superior fit — €28.02 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €18.45 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/fr/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €76.29 at Amazon

## Where to buy

- Lookfantastic: €15.18 (https://www.lookfantastic.fr/p/la-roche-posay-cicaplast-b5-soothing-repairing-spray-100ml/13840295/)
Prices checked 10 Oct 2026.

## Ingredients

Water, Glycerin, Propanediol, Panthenol, Pentylene Glycol, Sodium Citrate, Mannose, Madecassoside, Manganese Gluconate, Sodium Chloride, Coco-Betaine, Copper Gluconate, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin (this page)
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin