# La Mer The Regenerating Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [La Mer](https://lovi.care/skincare/fr/brands/la-mer)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your combination skin, the yeast extract and algae extract work synergistically to promote skin regeneration and improve texture and elasticity. Glycerin and dipotassium glycyrrhizate provide essential hydration and soothing effects, which are beneficial for managing your acne, blemishes, and breakouts.
- The inclusion of saccharomyces lysate extract and yeast faex extract further supports your skin's barrier repair and offers antioxidant protection, enhancing overall skin health.
- This formula is safe for your skin, as it contains no harsh or prohibited ingredients and poses no risk of irritation for combination skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Miracle Broth, Acetyl Hexapeptide-8, Niacinamide, Algae Extract, Glycerin

## What the research says

- Topical application of 1% Fucus vesiculosus extract gel twice daily for five weeks significantly decreased skin thickness and improved elasticity in human cheek skin compared with controls. ([Journal of Cosmetic Science, 2002](https://pubmed.ncbi.nlm.nih.gov/11917251/))
- Dipotassium glycyrrhizinate-loaded hydroxypropyl chitosan and poly(N-isopropylacrylamide) hydrogels applied to wounds in a mouse full-thickness skin defect model resulted in rapid wound closure, efficient tissue remolding, collagen deposition, and decreased inflammation compared to commercial Tegaderm film and 3M dressing controls. ([Acta Biomaterialia, 2022](https://pubmed.ncbi.nlm.nih.gov/35245682/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Treatment with lipid algae extract reduced the level of oxidized proteins in human keratinocytes and stratum corneum skin cells. ([Annals of the New York Academy of Sciences, 2004](https://pubmed.ncbi.nlm.nih.gov/15247018/))
- Topical astaxanthin-loaded algae extract hydrogel and lipogel formulations exhibited the highest antioxidant activity and successful in vitro release, suggesting their potential as anti-aging formulations. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29745467/))
- Antarctic marine algae extracts increased cell viability, protected against inflammation, and enhanced the barrier integrity of human intestinal and keratinocyte cell lines damaged by lipopolysaccharide or ultraviolet radiation. ([Marine Drugs, 2022](https://pubmed.ncbi.nlm.nih.gov/36135751/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))

## What reviewers say

Users with dry, mature, or sensitive skin frequently praise this serum for its immediate soothing and plumping effects, often noting a visible improvement in skin texture and radiance. Many experience hydration and a reduction in fine lines, though a significant portion of reviewers feel the anti-aging results do not justify the extremely high price point compared to other market alternatives.

- Liked: Deeply Hydrating (mostly mentioned)
- Disliked: Extremely High Price (mostly mentioned)
- Liked: Luxurious Feel (often mentioned)
- Liked: Smooths Skin Texture (often mentioned)
- Liked: Soothing & Calming (sometimes noted)
- Disliked: Poor Pump Design (sometimes noted)
- Disliked: Caused Breakouts/Irritation (rarely noted)
- Disliked: Strong Fragrance (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes La Mer The Regenerating Serum a great fit for acne-prone skin?

La Mer The Regenerating Serum is a great fit for acne-prone skin because glycerin and dipotassium glycyrrhizate provide essential hydration and soothing effects that help manage breakouts. Additionally, yeast extract and algae extract promote skin regeneration, while saccharomyces lysate extract supports barrier repair with a low risk of irritation.
Sources: [Acta Biomaterialia, 2022](https://pubmed.ncbi.nlm.nih.gov/35245682/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit for acne-prone skin because ingredients like glycerin and dipotassium glycyrrhizate provide essential hydration and soothing effects that help manage breakouts. Additionally, yeast extract and algae extract work together to promote skin regeneration and improve overall texture.
Sources: [Acta Biomaterialia, 2022](https://pubmed.ncbi.nlm.nih.gov/35245682/)

### What does Miracle Broth do for acne-prone skin?

Miracle Broth is unlikely to suit acne-prone skin well because it lacks the ingredients needed to clear breakouts and balance oil. Acne-prone skin needs lightweight, non-greasy ingredients that calm redness and keep pores clear, such as azelaic acid or plant oils with a high linoleic acid to oleic acid ratio.
Sources: [Postepy Dermatologii I Alergologii, 2023](https://pubmed.ncbi.nlm.nih.gov/38282869/), [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/28707186/)

### What does Argireline do for acne-prone skin?

Argireline is not typically targeted for acne-prone skin, as it is primarily used to smooth fine lines and reduce wrinkles by relaxing facial movements. While it helps keep skin smooth, acne-prone skin generally needs ingredients that clear pores, calm redness, and balance oil production.

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, though some serums may also be used in the morning or twice a day. Applying it in the evening offers extra safety around sun exposure and keeps the routine simple.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first, letting it absorb, and then following with your retinol product. This approach helps deliver soothing hydration to your skin while minimizing potential dryness or irritation from the retinol.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

This treatment is a great fit for your acne-prone skin, and you can safely use it in the evening. Lovi routines place treatments in the evening for simplicity and extra safety around sun exposure.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for acne-prone skin, as it is highly suitable and contains no harsh ingredients that risk irritation. Glycerin and dipotassium glycyrrhizate provide essential hydration and soothing effects that help manage blemishes and breakouts.
Sources: [Acta Biomaterialia, 2022](https://pubmed.ncbi.nlm.nih.gov/35245682/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, linalool, limonene, citronellol, and geraniol).

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €18.25 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/fr/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/fr/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €139.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/fr/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.98 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/fr/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €10.25 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/fr/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €17.90 at Amazon

## Where to buy

- Amazon.fr: €25.57 (https://www.amazon.fr/dp/B08XXLT4Y9?tag=lovi-care-web-product06-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Algae Extract, Dimethicone, Hdi Trimethylol Hexyllactone Crosspolymer, Hydrogenated Polyisobutene, Caprylic Capric Myristic Stearic Triglyceride, Polysilicone-11, Peg-8 Dimethicone, Peg-10 Dimethicone, Yeast Faex Extrait De Levure Extract, Citrus Aurantifolia Peel Extract, Sigesbeckia Orientalis Extract, Polygonum Cuspidatum Root Extract, Saccharomyces Lysate Extract, Sesamum Indicum Seed Oil, Eucalyptus Globulus Oil Leaf Eucalyptus Oil Leaf, Sesamum Indicum Seed Powder, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake Sunflower Seedcake, Prunus Amygdalus Dulcis Seed Meal Seed, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Vitis Vinifera Seed Extract Grape Seed Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Punica Granatum Fruit Juice, Bupleurum Falcatum Root Extract, Citrus Reticulata Peel Extract Tangerine Peel Extract, Narcissus Tazetta Bulb Extract, Mimosa Tenuiflora Bark Extract, Betula Alba Bark Extract, Chlorella Vulgaris Extract, Humulus Lupulus Extract, Laureth-4, Corallina Officinalis Extract, Glycine Soja Seed Extract Soybean Seed Extract, Micrococcus Lysate, Whey Lactis Proteine Du Petit-Lait Protein, Tartaric Acid, Glycerin, Hydrolyzed Wheat Protein, Laureth-23, Butylene Glycol, Ammonium Acryloyldimethyltaurate Beheneth-25 Methacrylate Crosspolymer, Sucrose, Coenzyme A, Acetyl Glucosamine, Caffeine, Dipalmitoyl Hydroxyproline, Linoleic Acid, Tetraacetylphytosphingosine, Alcaligenes Polysaccharides, Bifida Lysate Ferment, Pentylene Glycol, Dipotassium Glycyrrhizate, Palmitoyl Oligopeptide, Peg-8, Sorbitol, Tocopheryl Acetate, Eryngium Maritimum Extract, Sodium Hydroxide, Hydrogenated Lecithin, Hydroxypropyl Cyclodextrin, Nordihydroguaiaretic Acid, Cyclodextrin, Maltodextrin, Acetyl Hexapeptide-8, Glyceryl Polymethacrylate, Glycosaminoglycans, Gold, Tourmaline, Linolenic Acid, Silica, Ethylbisiminomethylguaiacol Manganese Chloride, Disodium Edta, Potassium Sorbate, Phenoxyethanol, Parfum, Hydroxycitronellal, Linalool, Limonene, Citronellol, Geraniol, Green 5 Ci 61570
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/acne-prone-skin (this page)
- Italy: https://lovi.care/skincare/it/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-mer/the-regenerating-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-mer/the-regenerating-serum/for/acne-prone-skin