# Isntree C-Niacin Toning Ampoule for dry skin

**Lovi Fit: Superior fit for dry skin.**
Dry Skin Fit: Superior · Effectiveness: Superior · Safety: High.

Page: https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [Isntree](https://lovi.care/skincare/fr/brands/isntree)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for dry skin.

## Why this fit

- Excellent suitability for your dry skin is provided by humectants like Glycerin and Sodium Hyaluronate, which draw moisture into the skin, complemented by Panthenol and Allantoin to support barrier repair.
- The high concentrations of 3-O-Ethyl Ascorbic Acid and Niacinamide offer significant brightening and evening of skin tone, addressing your concerns for dry or flaky skin.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing agents like Aloe Barbadensis Leaf Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/dry-skin): Superior (this page)
- [Combination skin](https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/oily-acne-prone-skin): Superior

## Key ingredients

Niacinamide, 3-O-Ethyl Ascorbic Acid Ascorbic Acid, Hippophae Rhamnoides Fruit Extract, Sodium Hyaluronate, Aloe Barbadensis Leaf Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of a sea buckthorn fruit extract formulation significantly reduced skin sebum secretion in 10 healthy human volunteers compared to the control base over an 8-week period. ([Journal of Pharmacy & Bioallied Sciences, 2010](https://pubmed.ncbi.nlm.nih.gov/21814424/))
- Topical emulsions containing Hippophae rhamnoides and Cassia fistula plant extracts significantly reduced skin sebum contents compared to placebo in patients with grade I and grade II acne vulgaris. ([Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25254008/))
- Topical application of a 5% Hippophae rhamnoides oil-in-water emulsion significantly improved skin hydration (p=0.0003) and transepidermal water loss (p=0.0087) compared to a placebo base formulation in 13 healthy male subjects over 84 days. ([Pakistan Journal of Pharmaceutical Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25362595/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))

## What reviewers say

This ampoule is frequently praised for its lightweight, fast-absorbing texture and its ability to gently brighten the skin, providing a natural glow. It is well-tolerated by sensitive and acne-prone skin types. Some users report that results are subtle and require consistent long-term use, with a few experiencing minor breakouts or noting the watery consistency can be difficult to handle.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Brightens and glows (often mentioned)
- Liked: Gentle on sensitive skin (often mentioned)
- Liked: Hydrating (sometimes noted)
- Disliked: Slow or minimal results (sometimes noted)
- Disliked: Minor breakouts (rarely noted)
- Disliked: Runny consistency (rarely noted)
- Disliked: Slight tackiness (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Isntree C-Niacin Toning Ampoule one of the best fits for dry skin?

This product is one of the best fits for dry skin because it draws moisture in with glycerin and sodium hyaluronate while using panthenol and allantoin to help repair your skin barrier. It also brightens and evens out your skin tone with niacinamide and vitamin C, and it is unlikely to cause irritation thanks to soothing aloe vera.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this ampoule a good fit for dry skin?

This ampoule is a great fit for dry skin thanks to glycerin and sodium hyaluronate, which draw moisture into the skin, along with panthenol and allantoin to support barrier repair. Niacinamide and vitamin C help brighten and even out skin tone, while aloe vera keeps the formula soothing and gentle.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### What does 3-O-Ethyl Ascorbic Acid do for dry skin?

3-O-Ethyl Ascorbic Acid helps brighten uneven skin and smooth out fine lines while supporting overall hydration. It is generally well-suited to improve skin appearance without causing significant irritation.
Sources: [Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36986679/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### Where does it go in a skincare routine for dry skin?

This treatment goes in the evening routine for dry skin. Putting it in the evening keeps things simple and provides extra safety around sun exposure, though some treatments like this can also be used in the morning or twice a day.

### Can I use this ampoule with retinol, and in what order?

You can use this ampoule with retinol by applying the ampoule first to draw in moisture and help calm the skin, followed by your retinol. The product is unlikely to cause irritation because it leaves out harsh ingredients and includes soothing agents.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use it?

You can use this treatment in your evening routine, applying it after cleansing and before your moisturizer. It is unlikely to cause irritation and helps keep your dry skin hydrated and bright.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can it clog pores, cause breakouts or purging for dry skin?

This product is unlikely to clog pores or cause breakouts on dry skin, as it features a safe formula with a low risk of irritation. Minor breakouts are only a slight, infrequent complaint among reviewers.

### Is this ampoule fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €18.25 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/fr/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — €57.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/fr/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €29.58 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/fr/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €7.50 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — €18.55 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/fr/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-skin) — Superior fit — €76.29 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Hippophae Rhamnoides Fruit Extract, Butylene Glycol, Pentylene Glycol, Glycerin, Betaine, Water, Niacinamide, Propanediol, Aloe Barbadensis Leaf Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Pumpkin Fruit Extract, Physalis Alkekengi Fruit Extract, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Ocimum Sanctum Leaf Extract, Beta-Glucan, Curcuma Longa Root Extract, Corallina Officinalis Extract, Brassica Oleracea Italica Extract, Coccinia Indica Fruit Extract, Moringa Oleifera Seed Oil, Boswellia Serrata Extract Resin, Bioflavonoids, Panthenol, Allantoin, Sodium Polyacrylate, Tocopherol, Polysorbate 80, 1,2-Hexanediol, Ethyl Hexanediol, Ammonium Acryloyldimethyltaurate Vp Copolymer, 3-O-Ethyl Ascorbic Acid, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Usnea Barbata Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- France: https://lovi.care/skincare/fr/p/isntree/c-niacin-toning-ampoule/for/dry-skin (this page)
- Italy: https://lovi.care/skincare/it/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/isntree/c-niacin-toning-ampoule/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/isntree/c-niacin-toning-ampoule/for/dry-skin