# iS Clinical Brightening Complex for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for France.

Brand: [iS Clinical](https://lovi.care/skincare/fr/brands/is-clinical)
Category: [Serums and treatments](https://lovi.care/skincare/fr/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers moderate brightening and evening of skin tone due to alpha-arbutin and tetrahexyldecyl ascorbate, which are beneficial for your dry skin by supporting an even complexion.
- The presence of sodium hyaluronate and glycerin provides essential hydration, while squalane offers emollient action, making it suitable for your dry skin type.
- The product is safe for your dry skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Alpha-Arbutin, Licorice Root Extract, Tetrahexyldecyl Ascorbate, Willow Bark Extract

## What the research says

- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Polyvinyl pyrrolidone-K90/Eudragit RL100 dissolving microneedle patches loaded with alpha-arbutin and resveratrol enhanced intradermal delivery by approximately 2.6 times compared to cream and slightly decreased the melanin index in human participants without causing skin irritation. ([Biomaterials Science, 2023](https://pubmed.ncbi.nlm.nih.gov/37183632/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- A botanical face cleanser with hops and willow bark extract continuously reduced skin sebum levels without reactive seborrhea after treatment in 21 healthy volunteers compared to a sodium laureth sulfate cleanser, with neither cleanser causing skin irritation. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/))
- Bioactive lipid nanocarriers co-loaded with willow bark or ivy leaf extracts and UV-filters provided pronounced UVA photoprotection up to an SPF-equivalent value of 13 and a maximum in vivo skin hydration effect of 97% when prepared with pomegranate oil. ([Nanomaterials, 2022](https://pubmed.ncbi.nlm.nih.gov/35889587/))
- A topical serum containing 0.5% salicin applied twice daily reduced visible signs of skin aging, including wrinkles and tactile roughness, in 30 female subjects over 12 weeks compared to baseline. ([Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20883292/))

## What reviewers say

Based on limited data, this product is highly praised for its ability to fade dark spots and hyperpigmentation, leading to a more even and radiant skin tone. Users with various skin types, including acne-prone and sensitive skin, find the formula to be gentle and non-irritating. A moderate number of users mention the high price point as a drawback, while a low frequency of reviews indicate no visible changes.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Evens skin tone (often mentioned)
- Liked: Gentle and non-irritating (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: No visible changes (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does iS Clinical Brightening Complex work for dry skin?

This product works moderately well for dry skin, providing helpful hydration and brightening ingredients like sodium hyaluronate and alpha-arbutin. It is safe and unlikely to cause irritation, though other products fit this skin type better. To work best for dry skin, a product of this type needs soothing ingredients, ceramides, niacinamide, and peptides that deliver deep hydration and support the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for dry skin?

Sodium hyaluronate and glycerin help bring hydration to dry skin, while squalane leaves it feeling soft, and alpha-arbutin and tetrahexyldecyl ascorbate help even out skin tone. To work best for dry skin, a product of this type needs rich, soothing hydrating ingredients like ceramides, niacinamide, or peptides that deeply nourish and support the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for dry skin?

Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### What does Alpha-Arbutin do for dry skin?

Alpha-arbutin is not primarily designed to hydrate dry skin, but advanced formulations containing it may help improve moisture content and elasticity while brightening dark spots. A dry skin type needs rich moisturizers with ingredients like ceramides, hyaluronic acid, and facial oils to properly nourish the skin barrier.
Sources: [Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/)

### Where does it go in a skincare routine for dry skin?

This treatment goes in the evening routine, applied after cleansing and before your moisturizer. A product of this type works best for dry skin when it includes hydrating ingredients like hyaluronic acid and softening oils.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying your retinol first and following with this product, or by using retinol on alternate nights to keep your dry skin calm. This product helps brighten skin tone with alpha-arbutin while providing hydration through sodium hyaluronate and glycerin, though dry skin generally benefits most from richer barrier-repair creams with heavier oils and ceramides.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

You can use this treatment in your evening routine, applying it after cleansing and before your moisturizer. For dry skin like yours, this type of product works best when it is paired with rich hydrators and nourishing oils that lock in moisture and prevent any dry flaking.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this cream clog pores, cause breakouts or purging for dry skin?

This cream is unlikely to clog pores, cause breakouts, or lead to purging for dry skin because it is formulated without harsh or pore-blocking ingredients and has a very safe profile. It helps keep skin calm and smooth while gently brightening your complexion.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Stearyl alcohol and cetearyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/fr/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €18.25 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/fr/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — €57.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/fr/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €29.58 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/fr/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €7.50 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/fr/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — €18.55 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/fr/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-skin) — Superior fit — €76.29 at Amazon

## Where to buy

No store in France has a checked price for this product, so the page shows none.

## Ingredients

Water, Willow Bark Extract, Sodium Hyaluronate, Saccharum Officinarum Extract Extrait De Canne À Sucre Extract, Vaccinium Myrtillus Leaf Extract Fruit, Ascophyllum Nodosum Extract, Tetrahexyldecyl Ascorbate, Glycerin, Squalane, Imperata Cylindrica Root Extract, Glyceryl Stearate, Alpha-Arbutin, Peg-100 Stearate, Peg-8 Smdi Copolymer, Triethanolamine, Polyporus Umbellatus Extract Mushroom Extract, Stearyl Alcohol, Cetearyl Alcohol, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Dimethicone, 1,2-Hexanediol, Caprylyl Glycol, Citrus Aurantium Dulcis Oil, Xanthan Gum, Hydrogenated Lecithin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/is-clinical/brightening-complex/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/is-clinical/brightening-complex/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/is-clinical/brightening-complex/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/is-clinical/brightening-complex/for/dry-skin
- France: https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/dry-skin (this page)
- Italy: https://lovi.care/skincare/it/p/is-clinical/brightening-complex/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/is-clinical/brightening-complex/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/is-clinical/brightening-complex/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/is-clinical/brightening-complex/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/is-clinical/brightening-complex/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/is-clinical/brightening-complex/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/is-clinical/brightening-complex/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/dry-skin